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2XKS
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BU of 2xks by Molmil
Prion-like conversion during amyloid formation at atomic resolution
Descriptor: BETA-2-MICROGLOBULIN
Authors:Eichner, T, Kalverda, A.P, Thompson, G.S, Radford, S.E, Homans, S.W.
Deposit date:2010-07-12
Release date:2011-02-16
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Conformational Conversion During Amyloid Formation at Atomic Resolution.
Mol.Cell, 41, 2011
2XKU
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BU of 2xku by Molmil
Prion-like conversion during amyloid formation at atomic resolution
Descriptor: BETA-2-MICROGLOBULIN
Authors:Eichner, T, Kalverda, A.P, Thompson, G.S, Homans, S.W, Radford, S.E.
Deposit date:2010-07-12
Release date:2011-02-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conformational Conversion During Amyloid Formation at Atomic Resolution.
Mol.Cell, 41, 2011
7BM5
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BU of 7bm5 by Molmil
Crystal structure of Fab1, the Fab fragment of the anti-BamA monoclonal antibody MAB1
Descriptor: Fab1 heavy chain, Fab1 light chain
Authors:White, P, Storek, K.M, Rutherford, S.T, Radford, S.E.
Deposit date:2021-01-19
Release date:2021-06-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding.
Nat Commun, 12, 2021
8QPZ
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BU of 8qpz by Molmil
CryoEM structure of recombinant DeltaN7 alpha-synuclein in PBS
Descriptor: Alpha-synuclein
Authors:Thacker, D, Wilkinson, M, Dewison, K.M, Ranson, N.A, Brockwell, D.J, Radford, S.E.
Deposit date:2023-10-03
Release date:2024-09-04
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Residues 2 to 7 of alpha-synuclein regulate amyloid formation via lipid-dependent and lipid-independent pathways.
Proc.Natl.Acad.Sci.USA, 121, 2024
8OHI
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BU of 8ohi by Molmil
Structure of the Fmoc-Tau-PAM4 Type 2 amyloid fibril
Descriptor: Microtubule-associated protein tau
Authors:Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J.
Deposit date:2023-03-21
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Local structural preferences in shaping tau amyloid polymorphism.
Nat Commun, 15, 2024
8OH2
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BU of 8oh2 by Molmil
Structure of the Tau-PAM4 Type 1 amyloid fibril
Descriptor: Microtubule-associated protein tau
Authors:Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J.
Deposit date:2023-03-20
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Local structural preferences in shaping tau amyloid polymorphism.
Nat Commun, 15, 2024
8OHP
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BU of 8ohp by Molmil
Structure of the Fmoc-Tau-PAM4 Type 3 amyloid fibril
Descriptor: Microtubule-associated protein tau
Authors:Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J.
Deposit date:2023-03-21
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Local structural preferences in shaping tau amyloid polymorphism.
Nat Commun, 15, 2024
8OI0
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BU of 8oi0 by Molmil
Structure of the Fmoc-Tau-PAM4 Type 4 amyloid fibril
Descriptor: Microtubule-associated protein tau
Authors:Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J.
Deposit date:2023-03-21
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Local structural preferences in shaping tau amyloid polymorphism.
Nat Commun, 15, 2024
6ZRF
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BU of 6zrf by Molmil
amyloid structure of amylin (IAPP - islet amyloid polypeptide)
Descriptor: Islet amyloid polypeptide
Authors:Gallardo, R.U, Iadanza, M.G, Ranson, N.A, Radford, S.E.
Deposit date:2020-07-13
Release date:2020-09-30
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly.
Nat.Struct.Mol.Biol., 27, 2020
6ZRQ
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BU of 6zrq by Molmil
two-protofilament amyloid structure of S20G variant of human amylin (IAPP - islet amyloid polypeptide)
Descriptor: Islet amyloid polypeptide
Authors:Gallardo, R.U, Iadanza, M.G, Ranson, N.A, Radford, S.E.
Deposit date:2020-07-14
Release date:2020-09-30
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly.
Nat.Struct.Mol.Biol., 27, 2020
6ZRR
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BU of 6zrr by Molmil
three-protofilament amyloid structure of S20G variant of human amylin (IAPP - Islet Amyloid Polypeptide)
Descriptor: Islet amyloid polypeptide
Authors:Gallardo, R.U, Iadanza, M.G, Ranson, N.A, Radford, S.E.
Deposit date:2020-07-14
Release date:2020-09-30
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly.
Nat.Struct.Mol.Biol., 27, 2020
1LDS
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BU of 1lds by Molmil
Crystal Structure of monomeric human beta-2-microglobulin
Descriptor: SODIUM ION, beta-2-microglobulin
Authors:Trinh, C.H, Smith, D.P, Kalverda, A.P, Phillips, S.E.V, Radford, S.E.
Deposit date:2002-04-09
Release date:2002-07-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of monomeric human beta-2-microglobulin reveals clues to its amyloidogenic properties.
Proc.Natl.Acad.Sci.USA, 99, 2002
2CO3
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BU of 2co3 by Molmil
Salmonella enterica SafA pilin, head-to-tail swapped dimer of Ntd1 mutant
Descriptor: SAFA PILUS SUBUNIT
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
8A7P
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BU of 8a7p by Molmil
beta-2-microglobulin DeltaN6 amyloid fibril form 2PFb
Descriptor: Beta-2-microglobulin form pI 5.3
Authors:Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
Deposit date:2022-06-21
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
8A7Q
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BU of 8a7q by Molmil
beta-2-microglobulin V27M amyloid fibril form 4PF
Descriptor: Beta-2-microglobulin
Authors:Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
Deposit date:2022-06-21
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
2CO6
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BU of 2co6 by Molmil
Salmonella enterica SafA pilin in complex with the SafB chaperone (Type I)
Descriptor: PUTATIVE FIMBRIAE ASSEMBLY CHAPERONE, PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CNY
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BU of 2cny by Molmil
Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide (I15A mutant)
Descriptor: PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO1
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BU of 2co1 by Molmil
Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide (F17A mutant)
Descriptor: PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CNZ
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BU of 2cnz by Molmil
Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide (V13A mutant)
Descriptor: PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO2
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BU of 2co2 by Molmil
Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide (F3A mutant)
Descriptor: SAFA N-TERMINAL EXTENSION, SAFA PILUS SUBUNIT
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO7
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BU of 2co7 by Molmil
Salmonella enterica SafA pilin in complex with the SafB chaperone (Type II)
Descriptor: PUTATIVE FIMBRIAE ASSEMBLY CHAPERONE, SAFA PILUS SUBUNIT, SULFATE ION
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
2CO4
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BU of 2co4 by Molmil
Salmonella enterica SafA pilin in complex with a 19-residue SafA Nte peptide
Descriptor: PUTATIVE OUTER MEMBRANE PROTEIN
Authors:Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G.
Deposit date:2006-05-25
Release date:2006-06-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism
Mol.Cell, 22, 2006
8A7O
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BU of 8a7o by Molmil
beta-2-microglobulin DeltaN6 amyloid fibril form 2PFa
Descriptor: Beta-2-microglobulin form pI 5.3
Authors:Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
Deposit date:2022-06-21
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
8A7T
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BU of 8a7t by Molmil
beta-2-microglobulin D76N amyloid fibril form 2PFa
Descriptor: Beta-2-microglobulin
Authors:Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A.
Deposit date:2022-06-21
Release date:2023-03-22
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Disease-relevant beta 2 -microglobulin variants share a common amyloid fold.
Nat Commun, 14, 2023
8AWT
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BU of 8awt by Molmil
IAPP S20G lag-phase fibril polymorph 2PF-P
Descriptor: Islet amyloid polypeptide
Authors:Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A.
Deposit date:2022-08-30
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural evolution of fibril polymorphs during amyloid assembly.
Cell, 186, 2023

 

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