2ILT | | HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE (HSD1) WITH NADP AND ADAMANTANE SULFONE INHIBITOR | | Descriptor: | Corticosteroid 11-beta-dehydrogenase isozyme 1, NICKEL (II) ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Longenecker, K.L., Sorensen, B., Judge, R., Qin, W., Link, J.T. | | Deposit date: | 2006-10-03 | | Release date: | 2007-04-03 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
|
|
2IRW | | HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE (HSD1) WITH NADP AND ADAMANTANE ETHER INHIBITOR | | Descriptor: | Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (1S,3R,4S,5S,7S)-4-{[2-(4-METHOXYPHENOXY)-2-METHYLPROPANOYL]AMINO}ADAMANTANE-1-CARBOXAMIDE | | Authors: | Longenecker, K.L., Patel, J.R., Russell, J., Qin, W. | | Deposit date: | 2006-10-16 | | Release date: | 2007-01-23 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation.
Bioorg.Med.Chem.Lett., 17, 2007
|
|
1MUI | | CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH LOPINAVIR. | | Descriptor: | protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE | | Authors: | Stoll, V., Qin, W., Stewart, K.D., Jakob, C., Park, C., Walter, K., Simmer, R.L., Helfrich, R., Bussiere, D., Kao, J., Kempf, D., Sham, H.L., Norbeck, D.W. | | Deposit date: | 2002-09-23 | | Release date: | 2002-10-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | X-ray Crystallographic Structure of ABT-378 (Lopinavir) Bound to HIV-1 Protease
BIOORG.MED.CHEM., 10, 2002
|
|
7C8V | | STRUCTURE OF SYBODY SR4 IN COMPLEX WITH THE SARS-COV-2 S RECEPTOR BINDING DOMAIN (RBD) | | Descriptor: | Synthetic nanobody SR4, Spike glycoprotein, GLYCEROL, ... | | Authors: | Li, T., Yao, H., Cai, H., Qin, W., Li, D. | | Deposit date: | 2020-06-03 | | Release date: | 2020-06-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Potent synthetic nanobodies against SARS-CoV-2 and molecular basis for neutratlization
To Be Published
|
|
7C8W | | STRUCTURE OF SYBODY MR17 IN COMPLEX WITH THE SARS-COV-2 S RECEPTOR-BINDING DOMAIN (RBD) | | Descriptor: | Synthetic nanobody MR17, Spike glycoprotein, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Li, T., Cai, H., Yao, H., Qin, W., Li, D. | | Deposit date: | 2020-06-03 | | Release date: | 2020-06-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Rapid selection of synthetic nanobodies against the receptor binding domain of SARS-CoV-2 S protein
To Be Published
|
|
7CAN | | STRUCTURE OF SYBODY MR17-K99Y IN COMPLEX WITH THE SARS-COV-2 S RECEPTOR-BINDING DOMAIN (RBD) | | Descriptor: | sybody MR17-K99Y, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Li, T., Yao, H., Cai, H., Qin, W., Li, D. | | Deposit date: | 2020-06-09 | | Release date: | 2020-06-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Potent synthetic nanobodies against SARS-CoV-2 and molecular basis for neutratlization
To Be Published
|
|
4HOV | | DYPB N246A IN COMPLEX WITH MANGANESE | | Descriptor: | DypB, PROTOPORPHYRIN IX CONTAINING FE, CHLORIDE ION, ... | | Authors: | Grigg, J.C., Singh, R., Eltis, L.D., Murphy, M.E.P. | | Deposit date: | 2012-10-22 | | Release date: | 2013-01-16 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Improved Manganese-Oxidizing Activity of DypB, a Peroxidase from a Lignolytic Bacterium.
Acs Chem.Biol., 8, 2013
|
|
5DIJ | | THE CRYSTAL STRUCTURE OF CT | | Descriptor: | TqaA, GLYCEROL, CHLORIDE ION | | Authors: | Zhang, J.R., Tang, Y., Zhou, J.H. | | Deposit date: | 2015-09-01 | | Release date: | 2016-09-07 | | Last modified: | 2016-11-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
|
|
5DLK | | THE CRYSTAL STRUCTURE OF CT MUTANT | | Descriptor: | TqaA, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE | | Authors: | Zhang, J.R., Tang, Y., Zhou, J.H. | | Deposit date: | 2015-09-06 | | Release date: | 2016-09-07 | | Last modified: | 2016-11-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
|
|
5EGF | | THE CRYSTAL STRUCTURE OF SEMET-CT | | Descriptor: | TqaA, 1,2-ETHANEDIOL, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE | | Authors: | Zhang, J.R., Tang, Y., Zhou, J.H. | | Deposit date: | 2015-10-27 | | Release date: | 2016-10-19 | | Last modified: | 2020-02-19 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
|
|
5EJD | | THE CRYSTAL STRUCTURE OF HOLO T3CT | | Descriptor: | TqaA, GLYCEROL, (R)-3-hydroxy-4-((3-((2-mercaptoethyl)amino)-3-oxopropyl)amino)-2,2-dimethyl-4-oxobutyl hydrogen phosphonate | | Authors: | Zhang, J.R., Tang, Y., Zhou, J.H. | | Deposit date: | 2015-11-01 | | Release date: | 2016-10-19 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
|
|
5EZY | | CRYSTAL STRUCTURE OF T2R-TTL-TACCALONOLIDE AJ COMPLEX | | Descriptor: | Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ... | | Authors: | Wang, Y., Yu, Y., Chen, Q., Yang, J. | | Deposit date: | 2015-11-27 | | Release date: | 2017-01-11 | | Last modified: | 2017-06-21 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Mechanism of microtubule stabilization by taccalonolide AJ
Nat Commun, 8, 2017
|
|
6IIW | |
