Author results

2ILT
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HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE (HSD1) WITH NADP AND ADAMANTANE SULFONE INHIBITOR
Descriptor:Corticosteroid 11-beta-dehydrogenase isozyme 1, NICKEL (II) ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Longenecker, K.L., Sorensen, B., Judge, R., Qin, W., Link, J.T.
Deposit date:2006-10-03
Release date:2007-04-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2IRW
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HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE (HSD1) WITH NADP AND ADAMANTANE ETHER INHIBITOR
Descriptor:Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (1S,3R,4S,5S,7S)-4-{[2-(4-METHOXYPHENOXY)-2-METHYLPROPANOYL]AMINO}ADAMANTANE-1-CARBOXAMIDE
Authors:Longenecker, K.L., Patel, J.R., Russell, J., Qin, W.
Deposit date:2006-10-16
Release date:2007-01-23
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation.
Bioorg.Med.Chem.Lett., 17, 2007
1MUI
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CRYSTAL STRUCTURE OF HIV-1 PROTEASE COMPLEXED WITH LOPINAVIR.
Descriptor:protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE
Authors:Stoll, V., Qin, W., Stewart, K.D., Jakob, C., Park, C., Walter, K., Simmer, R.L., Helfrich, R., Bussiere, D., Kao, J., Kempf, D., Sham, H.L., Norbeck, D.W.
Deposit date:2002-09-23
Release date:2002-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray Crystallographic Structure of ABT-378 (Lopinavir) Bound to HIV-1 Protease
BIOORG.MED.CHEM., 10, 2002
7C8V
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STRUCTURE OF SYBODY SR4 IN COMPLEX WITH THE SARS-COV-2 S RECEPTOR BINDING DOMAIN (RBD)
Descriptor:Synthetic nanobody SR4, Spike glycoprotein, GLYCEROL, ...
Authors:Li, T., Yao, H., Cai, H., Qin, W., Li, D.
Deposit date:2020-06-03
Release date:2020-06-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Potent synthetic nanobodies against SARS-CoV-2 and molecular basis for neutratlization
To Be Published
7C8W
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STRUCTURE OF SYBODY MR17 IN COMPLEX WITH THE SARS-COV-2 S RECEPTOR-BINDING DOMAIN (RBD)
Descriptor:Synthetic nanobody MR17, Spike glycoprotein, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, T., Cai, H., Yao, H., Qin, W., Li, D.
Deposit date:2020-06-03
Release date:2020-06-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Rapid selection of synthetic nanobodies against the receptor binding domain of SARS-CoV-2 S protein
To Be Published
7CAN
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STRUCTURE OF SYBODY MR17-K99Y IN COMPLEX WITH THE SARS-COV-2 S RECEPTOR-BINDING DOMAIN (RBD)
Descriptor:sybody MR17-K99Y, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, T., Yao, H., Cai, H., Qin, W., Li, D.
Deposit date:2020-06-09
Release date:2020-06-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Potent synthetic nanobodies against SARS-CoV-2 and molecular basis for neutratlization
To Be Published
4HOV
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DYPB N246A IN COMPLEX WITH MANGANESE
Descriptor:DypB, PROTOPORPHYRIN IX CONTAINING FE, CHLORIDE ION, ...
Authors:Grigg, J.C., Singh, R., Eltis, L.D., Murphy, M.E.P.
Deposit date:2012-10-22
Release date:2013-01-16
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Improved Manganese-Oxidizing Activity of DypB, a Peroxidase from a Lignolytic Bacterium.
Acs Chem.Biol., 8, 2013
5DIJ
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THE CRYSTAL STRUCTURE OF CT
Descriptor:TqaA, GLYCEROL, CHLORIDE ION
Authors:Zhang, J.R., Tang, Y., Zhou, J.H.
Deposit date:2015-09-01
Release date:2016-09-07
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
5DLK
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THE CRYSTAL STRUCTURE OF CT MUTANT
Descriptor:TqaA, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE
Authors:Zhang, J.R., Tang, Y., Zhou, J.H.
Deposit date:2015-09-06
Release date:2016-09-07
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
5EGF
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THE CRYSTAL STRUCTURE OF SEMET-CT
Descriptor:TqaA, 1,2-ETHANEDIOL, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE
Authors:Zhang, J.R., Tang, Y., Zhou, J.H.
Deposit date:2015-10-27
Release date:2016-10-19
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
5EJD
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THE CRYSTAL STRUCTURE OF HOLO T3CT
Descriptor:TqaA, GLYCEROL, (R)-3-hydroxy-4-((3-((2-mercaptoethyl)amino)-3-oxopropyl)amino)-2,2-dimethyl-4-oxobutyl hydrogen phosphonate
Authors:Zhang, J.R., Tang, Y., Zhou, J.H.
Deposit date:2015-11-01
Release date:2016-10-19
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
5EZY
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CRYSTAL STRUCTURE OF T2R-TTL-TACCALONOLIDE AJ COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Wang, Y., Yu, Y., Chen, Q., Yang, J.
Deposit date:2015-11-27
Release date:2017-01-11
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Mechanism of microtubule stabilization by taccalonolide AJ
Nat Commun, 8, 2017
6IIW
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CRYSTAL STRUCTURE OF HUMAN UHRF1 PHD FINGER IN COMPLEX WITH PAF15
Descriptor:E3 ubiquitin-protein ligase UHRF1, PCNA-associated factor, ZINC ION, ...
Authors:Arita, K., Kori, S.
Deposit date:2018-10-07
Release date:2019-10-09
Last modified:2020-03-18
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.
Nat Commun, 11, 2020
171313
PDB entries from 2020-11-18