5GIX | | HUMAN SERUM ALBUMIN-PALMITIC ACID-FE(HN3PIT)CL2 | | Descriptor: | Serum albumin, 14-piperidin-1-yl-11-oxa-13$l^{3}-thia-15,16$l^{4}-diaza-12$l^{3}-ferratetracyclo[8.7.0.0^{2,7}.0^{12,16}]heptadeca-1(10),2(7),3,5,8,13,16-heptaene, PALMITIC ACID | | Authors: | Yang, F., Qi, J., Wang, T. | | Deposit date: | 2016-06-25 | | Release date: | 2017-07-19 | | Method: | X-RAY DIFFRACTION (2.801 Å) | | Cite: | Developing Anticancer Ferric Prodrugs Based on the N-Donor Residues of Human Serum Albumin Carrier IIA Subdomain
J. Med. Chem., 59, 2016
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5F1I | | MHC WITH 9-MER PEPTIDE | | Descriptor: | MHC class I DLA-88, Beta2M, 9-mer peptide | | Authors: | Liu, J., Chai, Y., QI, J., Gao, G.F. | | Deposit date: | 2015-11-30 | | Release date: | 2016-11-30 | | Method: | X-RAY DIFFRACTION (2.904 Å) | | Cite: | Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
J Immunol., 197, 2016
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5F1N | | MHC COMPLEXED TO 11MER PEPTIDE | | Descriptor: | MHC class I antigen, Beta-2-microglobulin, Peptide from Cytochrome P450 family 1 subfamily B polypeptide 1 | | Authors: | Liu, J., Chai, Y., Qi, J., Gao, G.F. | | Deposit date: | 2015-11-30 | | Release date: | 2016-11-30 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
J Immunol., 197, 2016
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5JYY | | STRUCTURE-BASED TETRAVALENT ZANAMIVIR WITH POTENT INHIBITORY ACTIVITY AGAINST DRUG-RESISTANT INFLUENZA VIRUSES | | Descriptor: | Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... | | Authors: | Fu, L., Wu, Y., Bi, Y., Zhang, S., Lv, X., Qi, J., Li, Y., Lu, X., Yan, J., Gao, G.F., Li, X. | | Deposit date: | 2016-05-15 | | Release date: | 2016-06-29 | | Last modified: | 2018-10-24 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
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3I6K | | NEWLY IDENTIFIED EPITOPE FROM SARS-COV MEMBRANE PROTEIN COMPLEXED WITH HLA-A*0201 | | Descriptor: | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ... | | Authors: | Liu, J., Sun, Y., Qi, J., Chu, F., Wu, H., Gao, F., Li, T., Yan, J., Gao, G.F. | | Deposit date: | 2009-07-07 | | Release date: | 2010-06-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
J Infect Dis, 202, 2010
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3MGM | | CRYSTAL STRUCTURE OF HUMAN NUDT16 | | Descriptor: | U8 snoRNA-decapping enzyme | | Authors: | Yan, J., Lu, G., Zhang, J., Qi, J., Li, Z., Gao, F. | | Deposit date: | 2010-04-07 | | Release date: | 2011-04-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.801 Å) | | Cite: | Crystal structure and the template mRNA decapping activity of human NUDT16
To be Published
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3RE9 | | CRYSTAL STRUCTURE OF SORTASEC1 FROM STREPTOCOCCUS SUIS | | Descriptor: | Sortase-like protein | | Authors: | Lu, G., Qi, J., Gao, F., Yan, J., Tang, J., Gao, G.F. | | Deposit date: | 2011-04-04 | | Release date: | 2011-06-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A novel "open-form" structure of sortaseC from Streptococcus suis
Proteins, 2011
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3RL1 | | HIV RT DERIVED PEPTIDE COMPLEXED TO HLA-A*0301 | | Descriptor: | HLA class I histocompatibility antigen, A-3 alpha chain, Beta-2-microglobulin, ... | | Authors: | Zhang, S., Liu, J., Cheng, H., Tan, S., Qi, J., Yan, J., Gao, G.F. | | Deposit date: | 2011-04-19 | | Release date: | 2012-02-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
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3RL2 | | HIV NEF DERIVED PEPTIDE NEF73 COMPLEXED TO HLA-A*0301 | | Descriptor: | HLA class I histocompatibility antigen, A-3 alpha chain, Beta-2-microglobulin, ... | | Authors: | Zhang, S., Liu, J., Cheng, H., Tan, S., Qi, J., Yan, J., Gao, G.F. | | Deposit date: | 2011-04-19 | | Release date: | 2012-02-29 | | Method: | X-RAY DIFFRACTION (2.386 Å) | | Cite: | Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
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3S91 | | CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD3 IN COMPLEX WITH THE INHIBITOR JQ1 | | Descriptor: | Bromodomain-containing protein 3, (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, ISOPROPYL ALCOHOL | | Authors: | Filippakopoulos, P., Picaud, S., Qi, J., Keates, T., Felletar, I., Fedorov, O., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bradner, J.E., Knapp, S., Structural Genomics Consortium (SGC) | | Deposit date: | 2011-05-31 | | Release date: | 2011-06-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Crystal Structure of the first bromodomain of human BRD3 in complex with the inhibitor JQ1
To be Published
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3S92 | | CRYSTAL STRUCTURE OF THE SECOND BROMODOMAIN OF HUMAN BRD3 IN COMPLEX WITH THE INHIBITOR JQ1 | | Descriptor: | Bromodomain-containing protein 3, (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL | | Authors: | Filippakopoulos, P., Picaud, S., Qi, J., Keates, T., Felletar, I., Fedorov, O., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bradner, J.E., Knapp, S., Structural Genomics Consortium (SGC) | | Deposit date: | 2011-05-31 | | Release date: | 2011-06-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1
To be Published
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3TI3 | | CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR | | Descriptor: | Neuraminidase, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ... | | Authors: | Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F. | | Deposit date: | 2011-08-20 | | Release date: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
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3TI4 | | CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR OCTANOATE | | Descriptor: | Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... | | Authors: | Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F. | | Deposit date: | 2011-08-20 | | Release date: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.602 Å) | | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
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3TI5 | | CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH ZANAMIVIR | | Descriptor: | Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... | | Authors: | Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F. | | Deposit date: | 2011-08-20 | | Release date: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
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3TI6 | | CRYSTAL STRUCTURE OF 2009 PANDEMIC H1N1 NEURAMINIDASE COMPLEXED WITH OSELTAMIVIR | | Descriptor: | Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... | | Authors: | Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F. | | Deposit date: | 2011-08-20 | | Release date: | 2011-11-23 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
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3TI8 | | CRYSTAL STRUCTURE OF INFLUENZA A VIRUS NEURAMINIDASE N5 COMPLEXED WITH LANINAMIVIR | | Descriptor: | Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F. | | Deposit date: | 2011-08-20 | | Release date: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.601 Å) | | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
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3TIA | | CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR | | Descriptor: | Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F. | | Deposit date: | 2011-08-20 | | Release date: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
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3TIB | | CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH LANINAMIVIR OCTANOATE | | Descriptor: | Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F. | | Deposit date: | 2011-08-20 | | Release date: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
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3TIC | | CRYSTAL STRUCTURE OF 1957 PANDEMIC H2N2 NEURAMINIDASE COMPLEXED WITH ZANAMIVIR | | Descriptor: | Neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Vavricka, C.J., Li, Q., Wu, Y., Qi, J., Wang, M., Liu, Y., Gao, F., Liu, J., Feng, E., He, J., Wang, J., Liu, H., Jiang, H., Gao, G.F. | | Deposit date: | 2011-08-20 | | Release date: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition
Plos Pathog., 7, 2011
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3TO2 | | STRUCTURE OF HLA-A*0201 COMPLEXED WITH PEPTIDE MD3-C9 DERIVED FROM A CLUSTERING REGION OF RESTRICTED CYTOTOXIC T LYMPHOCYTE EPITOPE FROM SARS-COV M PROTEIN | | Descriptor: | MHC class I antigen, Beta-2-microglobulin, Md3-C9 peptide derived from Membrane glycoprotein | | Authors: | Liu, J., Qi, J., Gao, F., Yan, J., Gao, G.F. | | Deposit date: | 2011-09-03 | | Release date: | 2012-08-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Functional and Structural Definition of a Clustering Region of HLA-A2-restricted Cytotoxic T Lymphocyte Epitopes
Sci.Technology Rev., 29, 2011
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3U82 | | BINDING OF HERPES SIMPLEX VIRUS GLYCOPROTEIN D TO NECTIN-1 EXPLOITS HOST CELL ADHESION | | Descriptor: | Envelope glycoprotein D, Poliovirus receptor-related protein 1 | | Authors: | Zhang, N., Yan, J., Lu, G., Guo, Z., Fan, Z., Wang, J., Shi, Y., Qi, J., Gao, G.F. | | Deposit date: | 2011-10-15 | | Release date: | 2012-03-21 | | Method: | X-RAY DIFFRACTION (3.164 Å) | | Cite: | Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion.
Nat Commun, 2, 2011
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3U83 | | CRYSTAL STRUCTURE OF NECTIN-1 | | Descriptor: | Poliovirus receptor-related protein 1, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE | | Authors: | Zhang, N., Yan, J., Lu, G., Guo, Z., Fan, Z., Wang, J., Shi, Y., Qi, J., Gao, G.F. | | Deposit date: | 2011-10-15 | | Release date: | 2012-03-21 | | Method: | X-RAY DIFFRACTION (2.499 Å) | | Cite: | Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion.
Nat Commun, 2, 2011
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4DFH | | CRYSTAL STRUCTURE OF CELL ADHESION MOLECULE NECTIN-2/CD112 VARIABLE DOMAIN | | Descriptor: | Poliovirus receptor-related protein 2 | | Authors: | Liu, J., Qian, X., Chen, Z., Xu, X., Gao, F., Zhang, S., Zhang, R., Qi, J., Gao, G.F., Yan, J. | | Deposit date: | 2012-01-23 | | Release date: | 2012-06-06 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
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4DFI | | CRYSTAL STRUCTURE OF CELL ADHESION MOLECULE NECTIN-2/CD112 MUTANT FAMP | | Descriptor: | Poliovirus receptor-related protein 2 | | Authors: | Liu, J., Qian, X., Chen, Z., Xu, X., Gao, F., Zhang, S., Zhang, R., Qi, J., Gao, G.F., Yan, J. | | Deposit date: | 2012-01-23 | | Release date: | 2012-06-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
J.Immunol., 188, 2012
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4E0R | | STRUCTURE OF THE CHICKEN MHC CLASS I MOLECULE BF2*0401 | | Descriptor: | MHC class I alpha chain 2, Beta-2 microglobulin, 8-MERIC PEPTIDE (FUS/TLS) | | Authors: | Zhang, J., Chen, Y., Qi, J., Gao, F., Kaufman, J., Xia, C., Gao, G.F. | | Deposit date: | 2012-03-05 | | Release date: | 2012-11-21 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | Narrow Groove and Restricted Anchors of MHC Class I Molecule BF2*0401 Plus Peptide Transporter Restriction Can Explain Disease Susceptibility of B4 Chickens.
J.Immunol., 189, 2012
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