Author results

5GIX
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HUMAN SERUM ALBUMIN-PALMITIC ACID-FE(HN3PIT)CL2
Descriptor:Serum albumin, 14-piperidin-1-yl-11-oxa-13$l^{3}-thia-15,16$l^{4}-diaza-12$l^{3}-ferratetracyclo[8.7.0.0^{2,7}.0^{12,16}]heptadeca-1(10),2(7),3,5,8,13,16-heptaene, PALMITIC ACID
Authors:Yang, F., Qi, J., Wang, T.
Deposit date:2016-06-25
Release date:2017-07-19
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Developing Anticancer Ferric Prodrugs Based on the N-Donor Residues of Human Serum Albumin Carrier IIA Subdomain
J. Med. Chem., 59, 2016
5F1I
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MHC WITH 9-MER PEPTIDE
Descriptor:MHC class I DLA-88, Beta2M, 9-mer peptide
Authors:Liu, J., Chai, Y., QI, J., Gao, G.F.
Deposit date:2015-11-30
Release date:2016-11-30
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
J Immunol., 197, 2016
5F1N
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MHC COMPLEXED TO 11MER PEPTIDE
Descriptor:MHC class I antigen, Beta-2-microglobulin, Peptide from Cytochrome P450 family 1 subfamily B polypeptide 1
Authors:Liu, J., Chai, Y., Qi, J., Gao, G.F.
Deposit date:2015-11-30
Release date:2016-11-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
J Immunol., 197, 2016
5YMV
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CRYSTAL STRUCTURE OF 9-MER PEPTIDE FROM INFLUENZA VIRUS IN COMPLEX WITH BF2*1201
Descriptor:Class I histocompatibility antigen, F10 alpha chain, Beta-2-microglobulin, ...
Authors:Xiao, J., Xiang, W., Qi, J., Chai, Y., Liu, W.J., Gao, G.F.
Deposit date:2017-10-22
Release date:2018-10-24
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I.
J Immunol., 201, 2018
5YMW
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CRYSTAL STRUCTURE OF 8-MER PEPTIDE FROM ROUS SARCOMA VIRUS IN COMPLEX WITH BF2*1201
Descriptor:Class I histocompatibility antigen, F10 alpha chain, Beta-2-microglobulin, ...
Authors:Xiao, J., Xiang, W., Qi, J., Chai, Y., Liu, W.J., Gao, G.F.
Deposit date:2017-10-22
Release date:2018-10-24
Last modified:2019-07-31
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I.
J Immunol., 201, 2018
5JYY
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STRUCTURE-BASED TETRAVALENT ZANAMIVIR WITH POTENT INHIBITORY ACTIVITY AGAINST DRUG-RESISTANT INFLUENZA VIRUSES
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Fu, L., Wu, Y., Bi, Y., Zhang, S., Lv, X., Qi, J., Li, Y., Lu, X., Yan, J., Gao, G.F., Li, X.
Deposit date:2016-05-15
Release date:2016-06-29
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
6KUK
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO VRNA PROMOTER IN MODE A CONFORMATION (CLASS A1)
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of influenza D virus polymerase bound to vRNA promoter in mode A conformation (class A1)
To Be Published
6KUP
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO VRNA PROMOTER IN MODE A CONFORMATION(CLASS A2)
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of influenza D virus polymerase bound to vRNA promoter in Mode A conformation(Class A2)
To Be Published
6KUR
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO VRNA PROMOTER IN MODE B CONFORMATION (CLASS B1)
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1)
To Be Published
6KUT
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO VRNA PROMOTER IN MODE B CONFORMATION (CLASS B2)
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:structure of influenza D virus apo polymerase
To Be Published
6KUU
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO VRNA PROMOTER IN MODE B CONFORMATION (CLASS B3)
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-12-11
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B3)
To Be Published
6KUV
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO CRNA PROMOTER IN CLASS 2
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-02
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of influenza D virus polymerase bound to cRNA promoter in Mode B conformation
To Be Published
6KV5
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STRUCTURE OF INFLUENZA D VIRUS APO POLYMERASE
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-09-03
Release date:2019-10-02
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of influenza D virus apo polymerase
To be published
5GZN
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
Descriptor:Genome polyprotein, Antibody Heavy chain, Antibody light chain
Authors:Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2016-09-29
Release date:2016-12-28
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5GZO
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
Descriptor:Genome polyprotein, Antibody heavy chain, Antibody light chain
Authors:Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
Deposit date:2016-09-29
Release date:2017-01-18
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.755 Å)
Cite:Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
3I6K
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NEWLY IDENTIFIED EPITOPE FROM SARS-COV MEMBRANE PROTEIN COMPLEXED WITH HLA-A*0201
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Liu, J., Sun, Y., Qi, J., Chu, F., Wu, H., Gao, F., Li, T., Yan, J., Gao, G.F.
Deposit date:2009-07-07
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes
J Infect Dis, 202, 2010
3MGM
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CRYSTAL STRUCTURE OF HUMAN NUDT16
Descriptor:U8 snoRNA-decapping enzyme
Authors:Yan, J., Lu, G., Zhang, J., Qi, J., Li, Z., Gao, F.
Deposit date:2010-04-07
Release date:2011-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Crystal structure and the template mRNA decapping activity of human NUDT16
To be Published
3MXF
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH THE INHIBITOR JQ1
Descriptor:Bromodomain-containing protein 4, (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, IODIDE ION, ...
Authors:Filippakopoulos, P., Picaud, S., Qi, J., Keates, T., Felletar, I., Fedorov, O., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bradner, J.E., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2010-05-07
Release date:2010-10-06
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Selective inhibition of BET bromodomains.
Nature, 468, 2010
3PWU
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AN IMMMUNODOMINANT CTL EPITOPE FROM RINDERPEST VIRUS PRESENTED BY CATTLE MHC CLASS I MOLECULE N*01801(BOLA-A11)
Descriptor:MHC class I antigen, Beta-2-microglobulin, IPA from Hemagglutinin glycoprotein
Authors:Li, X., Liu, J., Qi, J., Gao, F., Li, Q., Li, X., Zhang, N., Xia, C., Gao, G.F.
Deposit date:2010-12-09
Release date:2011-08-24
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides
J.Virol., 85, 2011
3PWV
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AN IMMMUNODOMINANT CTL EPITOPE FROM RINDERPEST VIRUS PRESENTED BY CATTLE MHC CLASS I MOLECULE N*01801 (BOLA-A11)
Descriptor:MHC class I antigen, Beta-2-microglobulin, 9-mer peptide from Hemagglutinin
Authors:Li, X., Liu, J., Qi, J., Gao, F., Li, Q., Li, X., Zhang, N., Xia, C., Gao, G.F.
Deposit date:2010-12-09
Release date:2011-08-24
Method:X-RAY DIFFRACTION (2.696 Å)
Cite:Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides
J.Virol., 85, 2011
3RE9
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CRYSTAL STRUCTURE OF SORTASEC1 FROM STREPTOCOCCUS SUIS
Descriptor:Sortase-like protein
Authors:Lu, G., Qi, J., Gao, F., Yan, J., Tang, J., Gao, G.F.
Deposit date:2011-04-04
Release date:2011-06-01
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel "open-form" structure of sortaseC from Streptococcus suis.
Proteins, 79, 2011
3RL1
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HIV RT DERIVED PEPTIDE COMPLEXED TO HLA-A*0301
Descriptor:HLA class I histocompatibility antigen, A-3 alpha chain, Beta-2-microglobulin, ...
Authors:Zhang, S., Liu, J., Cheng, H., Tan, S., Qi, J., Yan, J., Gao, G.F.
Deposit date:2011-04-19
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
3RL2
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HIV NEF DERIVED PEPTIDE NEF73 COMPLEXED TO HLA-A*0301
Descriptor:HLA class I histocompatibility antigen, A-3 alpha chain, Beta-2-microglobulin, ...
Authors:Zhang, S., Liu, J., Cheng, H., Tan, S., Qi, J., Yan, J., Gao, G.F.
Deposit date:2011-04-19
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2.386 Å)
Cite:Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
3S91
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CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD3 IN COMPLEX WITH THE INHIBITOR JQ1
Descriptor:Bromodomain-containing protein 3, (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, ISOPROPYL ALCOHOL
Authors:Filippakopoulos, P., Picaud, S., Qi, J., Keates, T., Felletar, I., Fedorov, O., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bradner, J.E., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2011-05-31
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal Structure of the first bromodomain of human BRD3 in complex with the inhibitor JQ1
To be Published
3S92
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CRYSTAL STRUCTURE OF THE SECOND BROMODOMAIN OF HUMAN BRD3 IN COMPLEX WITH THE INHIBITOR JQ1
Descriptor:Bromodomain-containing protein 3, (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL
Authors:Filippakopoulos, P., Picaud, S., Qi, J., Keates, T., Felletar, I., Fedorov, O., Muniz, J., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Bradner, J.E., Knapp, S., Structural Genomics Consortium (SGC)
Deposit date:2011-05-31
Release date:2011-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1
To be Published