7WBP

Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron variant spike glycoprotein in complex with its receptor human ACE2

Summary for 7WBP

• Entry DOI: 10.2210/pdb7wbp/pdb
• Descriptor: Angiotensin-converting enzyme 2, Spike protein S1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: complex, viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 96050.31

Authors

Qi, J.,Han, P. (deposition date: 2021-12-17, release date: 2022-01-19, Last modification date: 2023-11-29)

• Primary citation: Han, P.,Li, L.,Liu, S.,Wang, Q.,Zhang, D.,Xu, Z.,Han, P.,Li, X.,Peng, Q.,Su, C.,Huang, B.,Li, D.,Zhang, R.,Tian, M.,Fu, L.,Gao, Y.,Zhao, X.,Liu, K.,Qi, J.,Gao, G.F.,Wang, P.; Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2.; Cell, 185:630-640.e10, 2022; PubMed: 35093192; DOI: 10.1016/j.cell.2022.01.001

Experimental method

X-RAY DIFFRACTION (3 Å)