5GIX
Human serum albumin-Palmitic acid-Fe(Hn3piT)Cl2
Summary for 5GIX
Entry DOI | 10.2210/pdb5gix/pdb |
Descriptor | Serum albumin, 14-piperidin-1-yl-11-oxa-13$l^{3}-thia-15,16$l^{4}-diaza-12$l^{3}-ferratetracyclo[8.7.0.0^{2,7}.0^{12,16}]heptadeca-1(10),2(7),3,5,8,13,16-heptaene, PALMITIC ACID, ... (4 entities in total) |
Functional Keywords | ferric compound, anticancer mechanism, tumor targeting, therapeutic effect, immune system |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P02768 |
Total number of polymer chains | 2 |
Total formula weight | 136243.28 |
Authors | |
Primary citation | Qi, J.,Gou, Y.,Zhang, Y.,Yang, K.,Chen, S.,Liu, L.,Wu, X.,Wang, T.,Zhang, W.,Yang, F. Developing Anticancer Ferric Prodrugs Based on the N-Donor Residues of Human Serum Albumin Carrier IIA Subdomain J. Med. Chem., 59:7497-7511, 2016 Cited by PubMed: 27441502DOI: 10.1021/acs.jmedchem.6b00509 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.801 Å) |
Structure validation
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