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6VJT
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BU of 6vjt by Molmil
Co-crystals of broadly neutralizing antibody with the linear epitope from Hepatitis B surface antigen
Descriptor: Heavy Chain Fab Fragment of Monoclonal Ab15, Light Chain Fab Fragment of Monoclonal antibody A15, antigenic region 139-148 of Hepatitis B surface antigen protein
Authors:Oren, D.A, Nussenzweig, M.C, Wang, Q.
Deposit date:2020-01-17
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.782 Å)
Cite:A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations.
Cell Host Microbe, 28, 2020
1DQO
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BU of 1dqo by Molmil
Crystal structure of the cysteine rich domain of mannose receptor complexed with Acetylgalactosamine-4-sulfate
Descriptor: 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, MANNOSE RECEPTOR
Authors:Liu, Y, Chirino, A.J, Misulovin, Z, Leteux, C, Feizi, T, Nussenzweig, M.C, Bjorkman, P.J.
Deposit date:2000-01-04
Release date:2000-05-10
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the cysteine-rich domain of mannose receptor complexed with a sulfated carbohydrate ligand.
J.Exp.Med., 191, 2000
1DQG
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BU of 1dqg by Molmil
CRYSTAL STRUCTURE OF THE CYSTEINE RICH DOMAIN OF MANNOSE RECEPTOR
Descriptor: MANNOSE RECEPTOR, SULFATE ION
Authors:Liu, Y, Chirino, A.J, Misulovin, Z, Leteux, C, Feizi, T, Nussenzweig, M.C, Bjorkman, P.J.
Deposit date:2000-01-04
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the cysteine-rich domain of mannose receptor complexed with a sulfated carbohydrate ligand.
J.Exp.Med., 191, 2000
4LSU
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BU of 4lsu by Molmil
Crystal structure of broadly and potently neutralizing antibody VRC-PG20 in complex with HIV-1 clade A/E 93TH057 gp120
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Zhou, T, Moquin, S, Kwong, P.D.
Deposit date:2013-07-23
Release date:2013-08-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies.
Immunity, 39, 2013
5FEC
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BU of 5fec by Molmil
Crystal structure of 3BNC60 Fab germline precursor in complex with 426c.TM4deltaV1-3 gp120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.TM4deltaV1-3 gp120, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2015-12-16
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5FA2
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BU of 5fa2 by Molmil
Crystal structure of 426c.TM4deltaV1-3 p120
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, THIOCYANATE ION, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2015-12-10
Release date:2016-04-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
4YDI
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BU of 4ydi by Molmil
Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Zhou, T, Srivatsan, S, Kwong, P.D.
Deposit date:2015-02-22
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.452 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
7R8N
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BU of 7r8n by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C051
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C051 Fab Heavy Chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-06-26
Release date:2021-08-04
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7R8O
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BU of 7r8o by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C548
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:DeLaitsch, A.T, Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-06-26
Release date:2021-08-04
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7R8L
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BU of 7r8l by Molmil
Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody C099 and CR3022
Descriptor: C099 Fab Heavy Chain, C099 Fab Light Chain, CR3022 Fab heavy chain, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-06-26
Release date:2021-08-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7R8M
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BU of 7r8m by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C032
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:DeLaitsch, A.T, Barnes, C.O, Bjorkman, P.J.
Deposit date:2021-06-26
Release date:2021-08-04
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Immunity, 54, 2021
7RYV
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BU of 7ryv by Molmil
Anti-HIV neutralizing antibody Ab1573 Fab isolated from sequentially immunized macaques
Descriptor: Ab1573 Fab heavy chain, Ab1573 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2021-08-26
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7RYU
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BU of 7ryu by Molmil
Anti-HIV neutralizing antibody Ab1303 Fab isolated from sequentially immunized mcaques
Descriptor: Ab1303 Fab heavy chain, Ab1303 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2021-08-26
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
6XCM
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BU of 6xcm by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
6XCA
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BU of 6xca by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C105
Descriptor: C105 Heavy Chain, C105 Light Chain, SULFATE ION
Authors:Sharaf, N.G, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
6XCN
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BU of 6xcn by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
5T3S
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BU of 5t3s by Molmil
HIV gp140 trimer MD39-10MUTA in complex with Fabs PGT124 and 35022
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2016-08-26
Release date:2016-09-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Immunity, 45, 2016
5T3Z
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BU of 5t3z by Molmil
3.5 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074
Descriptor: 10-1074 Heavy Chain, 10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gristick, H.B, Bjorkman, P.J.
Deposit date:2016-08-26
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site.
Nat.Struct.Mol.Biol., 23, 2016
4JPW
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BU of 4jpw by Molmil
Crystal structure of broadly and potently neutralizing antibody 12a21 in complex with hiv-1 strain 93th057 gp120 mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY 12A21, ...
Authors:Acharya, P, Luongo, T, Zhou, T, Kwong, P.D.
Deposit date:2013-03-19
Release date:2013-04-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.
Cell(Cambridge,Mass.), 153, 2013
7RKS
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BU of 7rks by Molmil
Structure of the SARS-CoV receptor binding domain in complex with the human neutralizing antibody Fab fragment, C118
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, C118 Antibody Fab Heavy Chain, ...
Authors:Jette, C.A, Bjorkman, P.J, Barnes, C.O.
Deposit date:2021-07-22
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Cell Rep, 36, 2021
7RKU
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BU of 7rku by Molmil
Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C022
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C022 Antibody Fab Heavy Chain, C022 Antibody Fab Light Chain, ...
Authors:Jette, C.A, Bjorkman, P.J, Barnes, C.O.
Deposit date:2021-07-22
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Cell Rep, 36, 2021
7RKV
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BU of 7rkv by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C118 Fab Heavy Chain, C118 Fab Light Chain, ...
Authors:Barnes, C.O, Jette, C.A, Bjorkman, P.J.
Deposit date:2021-07-22
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies.
Cell Rep, 36, 2021
6ORO
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BU of 6oro by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ...
Authors:Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
Deposit date:2019-04-30
Release date:2019-06-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6ORQ
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BU of 6orq by Molmil
Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ...
Authors:Abernathy, M.E, Gristick, H.B, Bjorkman, P.J.
Deposit date:2019-04-30
Release date:2019-06-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
6OKP
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BU of 6okp by Molmil
B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074
Descriptor: 10-1074 Heavy Chain,10-1074 Heavy Chain, 10-1074 Light Chain,10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2019-04-14
Release date:2019-06-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019

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