Author results

4WQO
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STRUCTURE OF VHL-ELOB-ELOC-CUL2
Descriptor:Von Hippel-Lindau disease tumor suppressor, Transcription elongation factor B polypeptide 2, Transcription elongation factor B polypeptide 1, ...
Authors:Nguyen, H.C., Xiong, Y.
Deposit date:2014-10-22
Release date:2015-03-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex.
Structure, 23, 2015
6TZ4
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CRYOEM RECONSTRUCTION OF MEMBRANE-BOUND ESCRT-III FILAMENT COMPOSED OF CHMP1B+IST1 (RIGHT-HANDED)
Descriptor:Charged multivesicular body protein 1b, IST1 homolog
Authors:Nguyen, H.C., Frost, A.
Deposit date:2019-08-10
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6TZ5
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CRYOEM RECONSTRUCTION OF MEMBRANE-BOUND ESCRT-III FILAMENT COMPOSED OF CHMP1B+IST1 (LEFT-HANDED)
Descriptor:Charged multivesicular body protein 1b, IST1 homolog
Authors:Nguyen, H.C., Frost, A.
Deposit date:2019-08-10
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6TZ9
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CRYOEM RECONSTRUCTION OF MEMBRANE-BOUND ESCRT-III FILAMENT COMPOSED OF CHMP1B ONLY
Descriptor:Charged multivesicular body protein 1b
Authors:Nguyen, H.C., Frost, A.
Deposit date:2019-08-11
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6TZA
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CRYOEM RECONSTRUCTION OF ESCRT-III FILAMENT COMPOSED OF IST1 NTD R16E K27E DOUBLE MUTANT
Descriptor:IST1 homolog
Authors:Nguyen, H.C., Frost, A.
Deposit date:2019-08-11
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nat.Struct.Mol.Biol., 27, 2020
6O85
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ELECTRON CRYO-MICROSCOPY OF THE EUKARYOTIC TRANSLATION INITIATION FACTOR 2B BOUND TO EUKARYOTIC TRANSLATION INITIATION FACTOR 2 FROM HOMO SAPIENS
Descriptor:Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ...
Authors:Nguyen, H.C., Kenner, L.R., Frost, A.S.
Deposit date:2019-03-08
Release date:2019-05-15
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
6O9Z
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ELECTRON CRYO-MICROSCOPY OF THE EUKARYOTIC TRANSLATION INITIATION FACTOR 2B BOUND TO EUKARYOTIC TRANSLATION INITIATION FACTOR 2 FROM HOMO SAPIENS
Descriptor:Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ...
Authors:Nguyen, H.C., Kenner, L.R., Frost, A.S.
Deposit date:2019-03-15
Release date:2019-05-15
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
4WHJ
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MYXOVIRUS RESISTANCE PROTEIN 2 (MXB)
Descriptor:Interferon-induced GTP-binding protein Mx2
Authors:Xiong, Y., Fribourgh, J.L., Nguyen, H.C.
Deposit date:2014-09-22
Release date:2014-10-29
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Insight into HIV-1 Restriction by MxB.
Cell Host Microbe, 16, 2014
6CAJ
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ELECTRON CRYO-MICROSCOPY OF THE EUKARYOTIC TRANSLATION INITIATION FACTOR 2B FROM HOMO SAPIENS
Descriptor:Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit gamma, Translation initiation factor eIF-2B subunit alpha, ...
Authors:Tsai, J.C., Miller-Vedam, L.E., Anand, A.A., Jaishankar, P., Nguyen, H.C., Renslo, A.R., Frost, A., Walter, P.
Deposit date:2018-01-31
Release date:2018-04-11
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule.
Science, 359, 2018
7KKJ
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STRUCTURE OF ANTI-SARS-COV-2 SPIKE NANOBODY MNB6
Descriptor:Synthetic nanobody mNb6, SULFATE ION, CHLORIDE ION
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKK
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY NB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody Nb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKL
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY MNB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody mNb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
6O81
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ELECTRON CRYO-MICROSCOPY OF THE EUKARYOTIC TRANSLATION INITIATION FACTOR 2B BOUND TO TRANSLATION INITIATION FACTOR 2 FROM HOMO SAPIENS
Descriptor:Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ...
Authors:Nguyen, H., Kenner, L., Frost, A.
Deposit date:2019-03-08
Release date:2019-05-15
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
7KDT
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HUMAN TOM70 IN COMPLEX WITH SARS COV2 ORF9B
Descriptor:Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 2020
6E8G
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CRYOEM RECONSTRUCTION OF IST1-CHMP1B COPOLYMER FILAMENT BOUND TO SSDNA AT 2.9 ANGSTROM RESOLUTION
Descriptor:IST1 homolog, Charged multivesicular body protein 1b
Authors:Talledge, N., Frost, A., McCullough, J.
Deposit date:2018-07-29
Release date:2018-08-15
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The ESCRT-III proteins IST1 and CHMP1B assemble around nucleic acids
Biorxiv, 2018
6NIL
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CRYOEM STRUCTURE OF THE TRUNCATED HIV-1 VIF/CBFBETA/A3F COMPLEX
Descriptor:DNA dC->dU-editing enzyme APOBEC-3F, Core-binding factor subunit beta, Virion infectivity factor, ...
Authors:Hu, Y., Xiong, Y.
Deposit date:2018-12-29
Release date:2019-12-11
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of antagonism of human APOBEC3F by HIV-1 Vif.
Nat.Struct.Mol.Biol., 26, 2019
171588
PDB entries from 2020-11-25