6O9Z

Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens

Summary for 6O9Z

• Entry DOI: 10.2210/pdb6o9z/pdb
• EMDB information: 0664
• Descriptor: Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ... (6 entities in total)
• Functional Keywords: eukaryotic translation initiation factor 2b, eukaryotic translation initiation factor 2, translation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 600795.66

Authors

Nguyen, H.C.,Kenner, L.R.,Frost, A.S. (deposition date: 2019-03-15, release date: 2019-05-15, Last modification date: 2019-12-18)

• Primary citation: Kenner, L.R.,Anand, A.A.,Nguyen, H.C.,Myasnikov, A.G.,Klose, C.J.,McGeever, L.A.,Tsai, J.C.,Miller-Vedam, L.E.,Walter, P.,Frost, A.; eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.; Science, 364:491-495, 2019; PubMed: 31048491; DOI: 10.1126/science.aaw2922

Experimental method

ELECTRON MICROSCOPY (3.03 Å)