7L7G

Electron cryo-microscopy of the eukaryotic translation initiation factor 2B from Homo sapiens (updated model of PDB ID: 6CAJ)

Summary for 7L7G

• Entry DOI: 10.2210/pdb7l7g/pdb
• Related: 6CAJ
• EMDB information: 7443
• Descriptor: Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit gamma, Translation initiation factor eIF-2B subunit beta, ... (6 entities in total)
• Functional Keywords: translation; integrated stress response, translation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 526770.76

Authors

Tsai, J.C.,Miller-Vedam, L.E.,Anand, A.,Jaishankar, P.,Nguyen, H.C.,Wang, L.,Renslo, A.R.,Frost, A.,Walter, P. (deposition date: 2020-12-28, release date: 2021-03-24, Last modification date: 2024-03-06)

• Primary citation: Schoof, M.,Boone, M.,Wang, L.,Lawrence, R.,Frost, A.,Walter, P.; eIF2B conformation and assembly state regulates the integrated stress response.; Elife, 10:-, 2021; PubMed: 33688831; DOI: 10.7554/eLife.65703

Experimental method

ELECTRON MICROSCOPY (3 Å)