6CAJ
Electron cryo-microscopy of the eukaryotic translation initiation factor 2B from Homo sapiens
Summary for 6CAJ
Entry DOI | 10.2210/pdb6caj/pdb |
Related | 6caj |
EMDB information | 7442 7443 7444 |
Descriptor | Translation initiation factor eIF-2B subunit epsilon, Translation initiation factor eIF-2B subunit gamma, Translation initiation factor eIF-2B subunit alpha, ... (6 entities in total) |
Functional Keywords | guanine nucleotide exchange factor, translation initiation, isrib-bound, decameric complex, translation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 526770.76 |
Authors | Tsai, J.C.,Miller-Vedam, L.E.,Anand, A.A.,Jaishankar, P.,Nguyen, H.C.,Renslo, A.R.,Frost, A.,Walter, P. (deposition date: 2018-01-31, release date: 2018-04-11, Last modification date: 2019-11-20) |
Primary citation | Tsai, J.C.,Miller-Vedam, L.E.,Anand, A.A.,Jaishankar, P.,Nguyen, H.C.,Renslo, A.R.,Frost, A.,Walter, P. Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Science, 359:-, 2018 Cited by PubMed: 29599213DOI: 10.1126/science.aaq0939 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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