1Z8Y | | MAPPING THE E2 GLYCOPROTEIN OF ALPHAVIRUSES | | Descriptor: | Spike glycoprotein E1, Spike glycoprotein E2, Capsid protein C | | Authors: | Mukhopadhyay, S., Zhang, W., Gabler, S., Chipman, P.R., Strauss, E.G., Strauss, J.H., Baker, T.S., Kuhn, R.J., Rossmann, M.G. | | Deposit date: | 2005-03-31 | | Release date: | 2006-02-07 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Mapping the structure and function of the E1 and E2 glycoproteins in alphaviruses.
Structure, 14, 2006
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2IIR | |
4FRR | |
1P58 | | COMPLEX ORGANIZATION OF DENGUE VIRUS MEMBRANE PROTEINS AS REVEALED BY 9.5 ANGSTROM CRYO-EM RECONSTRUCTION | | Descriptor: | Major envelope protein E, Envelope protein M | | Authors: | Zhang, W., Chipman, P.R., Corver, J., Johnson, P.R., Zhang, Y., Mukhopadhyay, S., Baker, T.S., Strauss, J.H., Rossmann, M.G., Kuhn, R.J. | | Deposit date: | 2003-04-25 | | Release date: | 2003-11-04 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Visualization of membrane protein domains by cryo-electron microscopy of dengue virus
Nat.Struct.Biol., 10, 2003
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1NN8 | | CRYOEM STRUCTURE OF POLIOVIRUS RECEPTOR BOUND TO POLIOVIRUS | | Descriptor: | poliovirus receptor, coat protein VP1, coat protein VP2, ... | | Authors: | He, Y., Mueller, S., Chipman, P.R., Bator, C.M., Peng, X., Bowman, V.D., Mukhopadhyay, S., Wimmer, E., Kuhn, R.J., Rossmann, M.G. | | Deposit date: | 2003-01-13 | | Release date: | 2004-01-27 | | Last modified: | 2011-07-13 | | Method: | ELECTRON MICROSCOPY (15 Å) | | Cite: | Complexes of poliovirus serotypes with their common cellular receptor, CD155
J.Virol., 77, 2003
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4BW5 | | CRYSTAL STRUCTURE OF HUMAN TWO PORE DOMAIN POTASSIUM ION CHANNEL TREK2 (K2P10.1) | | Descriptor: | POTASSIUM CHANNEL SUBFAMILY K MEMBER 10, POTASSIUM ION, CADMIUM ION, ... | | Authors: | Pike, A.C.W., Dong, Y.Y., Dong, L., Quigley, A., Shrestha, L., Mukhopadhyay, S., Strain-Damerell, C., Goubin, S., Grieben, M., Shintre, C.A., Mackenzie, A., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N., Carpenter, E.P. | | Deposit date: | 2013-06-30 | | Release date: | 2013-07-31 | | Last modified: | 2019-03-06 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | K2P Channel Gating Mechanisms Revealed by Structures of Trek-2 and a Complex with Prozac
Science, 347, 2015
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4TWK | | CRYSTAL STRUCTURE OF HUMAN TWO PORE DOMAIN POTASSIUM ION CHANNEL TREK1 (K2P2.1) | | Descriptor: | Potassium channel subfamily K member 2, POTASSIUM ION, Octyl Glucose Neopentyl Glycol, ... | | Authors: | Pike, A.C.W., Dong, Y.Y., Tessitore, A., Goubin, S., Strain-Damerell, C., Mukhopadhyay, S., Kupinska, K., Wang, D., Chalk, R., Berridge, G., Grieben, M., Shrestha, L., Ang, J.H., Mackenzie, A., Quigley, A., Bushell, S.R., Shintre, C.A., Faust, B., Chu, A., Dong, L., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P. | | Deposit date: | 2014-06-30 | | Release date: | 2014-08-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of human two pore domain potassium ion channel TREK1 (K2P2.1)
To Be Published
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4XDJ | | CRYSTAL STRUCTURE OF HUMAN TWO PORE DOMAIN POTASSIUM ION CHANNEL TREK2 (K2P10.1) IN AN ALTERNATE CONFORMATION (FORM 2) | | Descriptor: | POTASSIUM CHANNEL SUBFAMILY K MEMBER 10, POTASSIUM ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | Authors: | Pike, A.C.W., Dong, Y.Y., Mackenzie, A., Mukhopadhyay, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2014-12-19 | | Release date: | 2015-03-18 | | Last modified: | 2015-04-01 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.
Science, 347, 2015
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4XDK | | CRYSTAL STRUCTURE OF HUMAN TWO PORE DOMAIN POTASSIUM ION CHANNEL TREK2 (K2P10.1) IN COMPLEX WITH NORFLUOXETINE | | Descriptor: | Potassium channel subfamily K member 10, POTASSIUM ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | Authors: | Pike, A.C.W., Dong, Y.Y., Mackenzie, A., Mukhopadhyay, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2014-12-19 | | Release date: | 2015-03-18 | | Last modified: | 2018-01-10 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.
Science, 347, 2015
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4XDL | | CRYSTAL STRUCTURE OF HUMAN TWO PORE DOMAIN POTASSIUM ION CHANNEL TREK2 (K2P10.1) IN COMPLEX WITH A BROMINATED FLUOXETINE DERIVATIVE. | | Descriptor: | Potassium channel subfamily K member 10, POTASSIUM ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | Authors: | Mackenzie, A., Pike, A.C.W., Dong, Y.Y., Mukhopadhyay, S., Ruda, G.F., Brennan, P.E., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2014-12-19 | | Release date: | 2015-03-18 | | Last modified: | 2018-01-10 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac.
Science, 347, 2015
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5K47 | | CRYOEM STRUCTURE OF THE HUMAN POLYCYSTIN-2/PKD2 TRP CHANNEL | | Descriptor: | Polycystin-2, N-ACETYL-D-GLUCOSAMINE | | Authors: | Pike, A.C.W., Grieben, M., Shintre, C.A., Tessitore, A., Shrestha, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Burgess-Brown, N.A., Huiskonen, J.T., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2016-05-20 | | Release date: | 2016-08-24 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).
Nat. Struct. Mol. Biol., 24, 2017
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1K4R | | STRUCTURE OF DENGUE VIRUS | | Descriptor: | MAJOR ENVELOPE PROTEIN E | | Authors: | Kuhn, R.J., Zhang, W., Rossmann, M.G., Pletnev, S.V., Corver, J., Lenches, E., Jones, C.T., Mukhopadhyay, S., Chipman, P.R., Strauss, E.G., Baker, T.S., Strauss, J.H. | | Deposit date: | 2001-10-08 | | Release date: | 2002-03-13 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (24 Å) | | Cite: | Structure of dengue virus: implications for flavivirus organization, maturation, and fusion.
Cell(Cambridge,Mass.), 108, 2002
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1LD4 | | PLACEMENT OF THE STRUCTURAL PROTEINS IN SINDBIS VIRUS | | Descriptor: | Coat protein C, GENERAL CONTROL PROTEIN GCN4, Spike glycoprotein E1, ... | | Authors: | Zhang, W., Mukhopadhyay, S., Pletnev, S.V., Baker, T.S., Kuhn, R.J., Rossmann, M.G. | | Deposit date: | 2002-04-08 | | Release date: | 2002-11-04 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (11.4 Å) | | Cite: | Placement of the Structural Proteins in Sindbis virus
J.VIROL., 76, 2002
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5C65 | | STRUCTURE OF THE HUMAN GLUCOSE TRANSPORTER GLUT3 / SLC2A3 | | Descriptor: | Solute carrier family 2, facilitated glucose transporter member 3, Octyl Glucose Neopentyl Glycol, ... | | Authors: | Pike, A.C.W., Quigley, A., Chu, A., Tessitore, A., Xia, X., Mukhopadhyay, S., Wang, D., Kupinska, K., Strain-Damerell, C., Chalk, R., Burgess-Brown, N.A., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2015-06-22 | | Release date: | 2015-07-08 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of the human glucose transporter GLUT3 / SLC2A3
To Be Published
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5OCH | | THE CRYSTAL STRUCTURE OF HUMAN ABCB8 IN AN OUTWARD-FACING STATE | | Descriptor: | ATP-binding cassette sub-family B member 8, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Faust, B., Pike, A.C.W., Shintre, C.A., Quiqley, A.M., Chu, A., Barr, A., Shrestha, L., Mukhopadhyay, S., Borkowska, O., Chalk, R., Burgess-Brown, N.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2017-06-30 | | Release date: | 2018-07-25 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | The crystal structure of human ABCB8 in an outward-facing state
To Be Published
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6GYN | | STRUCTURE OF HUMAN HCN4 HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED ION CHANNEL | | Descriptor: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE | | Authors: | Shintre, C.A., Pike, A.C.W., Tessitore, A., Young, M., Bushell, S.R., Strain-Damerell, C., Mukhopadhyay, S., Burgess-Brown, N.A., Huiskonen, J.T., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2018-06-30 | | Release date: | 2019-05-08 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
To Be Published
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6GYO | | STRUCTURE OF HUMAN HCN4 HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED ION CHANNEL IN COMPLEX WITH CAMP | | Descriptor: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | Authors: | Shintre, C.A., Pike, A.C.W., Tessitore, A., Young, M., Bushell, S.R., Strain-Damerell, C., Mukhopadhyay, S., Burgess-Brown, N.A., Huiskonen, J.T., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2018-06-30 | | Release date: | 2019-05-01 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
To Be Published
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5LEV | | CRYSTAL STRUCTURE OF HUMAN UDP-N-ACETYLGLUCOSAMINE-DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (DPAGT1) (V264G MUTANT) | | Descriptor: | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, UNKNOWN LIGAND | | Authors: | Pike, A.C.W., Dong, Y.Y., Chu, A., Tessitore, A., Goubin, S., Dong, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Berridge, G., Wang, D., Kupinska, K., Belaya, K., Beeson, D., Burgess-Brown, N., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2016-06-30 | | Release date: | 2016-12-28 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
Cell, 175, 2018
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5O5E | | CRYSTAL STRUCTURE OF HUMAN UDP-N-ACETYLGLUCOSAMINE-DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (DPAGT1) (V264G MUTANT) IN COMPLEX WITH TUNICAMYCIN | | Descriptor: | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Tunicamycin, ... | | Authors: | Pike, A.C.W., Dong, Y.Y., Chu, A., Tessitore, A., Goubin, S., Dong, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Berridge, G., Wang, D., Kupinska, K., Belaya, K., Beeson, D., Burgess-Brown, N., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2017-06-01 | | Release date: | 2018-02-28 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
Cell, 175, 2018
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6FM9 | | CRYSTAL STRUCTURE OF HUMAN UDP-N-ACETYLGLUCOSAMINE-DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (DPAGT1) | | Descriptor: | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE | | Authors: | Pike, A.C.W., Dong, Y.Y., Chu, A., Tessitore, A., Goubin, S., Dong, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Berridge, G., Wang, D., Kupinska, K., Belaya, K., Beeson, D., Burgess-Brown, N., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2018-01-30 | | Release date: | 2018-02-28 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
Cell, 175, 2018
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6FWZ | | CRYSTAL STRUCTURE OF HUMAN UDP-N-ACETYLGLUCOSAMINE-DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE (DPAGT1) (V264G MUTANT) IN COMPLEX WITH UDP-GLCNAC | | Descriptor: | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, MAGNESIUM ION, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ... | | Authors: | Pike, A.C.W., Dong, Y.Y., Chu, A., Tessitore, A., Goubin, S., Dong, L., Mukhopadhyay, S., Mahajan, P., Chalk, R., Berridge, G., Wang, D., Kupinska, K., Belaya, K., Beeson, D., Burgess-Brown, N., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2018-03-07 | | Release date: | 2018-07-25 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design.
Cell, 175, 2018
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5OC9 | | CRYSTAL STRUCTURE OF HUMAN TMEM16K / ANOCTAMIN 10 | | Descriptor: | Anoctamin-10, CALCIUM ION, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate | | Authors: | Bushell, S.R., Pike, A.C.W., Chu, A., Tessitore, A., Rotty, B., Mukhopadhyay, S., Kupinska, K., Shrestha, L., Borkowska, O., Chalk, R., Burgess-Brown, N.A., Love, J., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2017-06-29 | | Release date: | 2018-07-25 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
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6R65 | | CRYSTAL STRUCTURE OF HUMAN TMEM16K / ANOCTAMIN 10 (FORM 2) | | Descriptor: | Anoctamin-10, CALCIUM ION | | Authors: | Bushell, S.R., Pike, A.C.W., Chu, A., Tessitore, A., Rotty, B., Mukhopadhyay, S., Kupinska, K., Shrestha, L., Borkowska, O., Chalk, R., Burgess-Brown, N.A., Love, J., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2019-03-26 | | Release date: | 2019-05-01 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
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6R7X | | CRYOEM STRUCTURE OF CALCIUM-BOUND HUMAN TMEM16K / ANOCTAMIN 10 IN DETERGENT (2MM CA2+, CLOSED FORM) | | Descriptor: | Anoctamin-10, CALCIUM ION, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | Authors: | Pike, A.C.W., Bushell, S.R., Shintre, C.A., Tessitore, A., Baronina, A., Chu, A., Mukhopadhyay, S., Shrestha, L., Chalk, R., Burgess-Brown, N.A., Love, J., Huiskonen, J.T., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2019-03-29 | | Release date: | 2019-05-01 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
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6R7Y | | CRYOEM STRUCTURE OF CALCIUM-BOUND HUMAN TMEM16K / ANOCTAMIN 10 IN DETERGENT (LOW CA2+, CLOSED FORM) | | Descriptor: | Anoctamin-10, CALCIUM ION | | Authors: | Pike, A.C.W., Bushell, S.R., Shintre, C.A., Tessitore, A., Chu, A., Mukhopadhyay, S., Shrestha, L., Chalk, R., Burgess-Brown, N.A., Love, J., Huiskonen, J.T., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC) | | Deposit date: | 2019-03-29 | | Release date: | 2019-05-01 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.
Nat Commun, 10, 2019
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