6JTZ

Crystal Structure of hRecQ1_D2-Zn-WH containing mutation on beta-hairpin

Summary for 6JTZ

• Entry DOI: 10.2210/pdb6jtz/pdb
• Descriptor: ATP-dependent DNA helicase Q1, ZINC ION (3 entities in total)
• Functional Keywords: recq1, helicase, dna-binding protein, zn-binding domain, dna binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 80382.11

Authors

Das, T.,Mukhopadhyay, S.,Bose, M.,Das, A.K.,Ganguly, A. (deposition date: 2019-04-12, release date: 2020-04-15, Last modification date: 2023-11-22)

• Primary citation: Mukhopadhyay, S.,Das, T.,Bose, M.,Jain, C.K.,Chakraborty, M.,Mukherjee, S.,Shikha, K.,Das, A.K.,Ganguly, A.; Residues at the interface between zinc binding and winged helix domains of human RECQ1 play a significant role in DNA strand annealing activity.; Nucleic Acids Res., 2021; PubMed: 34751402; DOI: 10.1093/nar/gkab968

Experimental method

X-RAY DIFFRACTION (2.797 Å)