6JTZ
Crystal Structure of hRecQ1_D2-Zn-WH containing mutation on beta-hairpin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004386 | molecular_function | helicase activity |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006310 | biological_process | DNA recombination |
| A | 0043138 | molecular_function | 3'-5' DNA helicase activity |
| B | 0004386 | molecular_function | helicase activity |
| B | 0006260 | biological_process | DNA replication |
| B | 0006281 | biological_process | DNA repair |
| B | 0006310 | biological_process | DNA recombination |
| B | 0043138 | molecular_function | 3'-5' DNA helicase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 701 |
| Chain | Residue |
| A | CYS453 |
| A | CYS471 |
| A | CYS475 |
| A | CYS478 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 701 |
| Chain | Residue |
| B | CYS453 |
| B | CYS471 |
| B | CYS475 |
| B | CYS478 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 302 |
| Details | Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19151156","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25831490","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2V1X","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2WWY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U7D","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
