6JTZ
Crystal Structure of hRecQ1_D2-Zn-WH containing mutation on beta-hairpin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004386 | molecular_function | helicase activity |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006310 | biological_process | DNA recombination |
| A | 0043138 | molecular_function | 3'-5' DNA helicase activity |
| B | 0004386 | molecular_function | helicase activity |
| B | 0006260 | biological_process | DNA replication |
| B | 0006281 | biological_process | DNA repair |
| B | 0006310 | biological_process | DNA recombination |
| B | 0043138 | molecular_function | 3'-5' DNA helicase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 701 |
| Chain | Residue |
| A | CYS453 |
| A | CYS471 |
| A | CYS475 |
| A | CYS478 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 701 |
| Chain | Residue |
| B | CYS453 |
| B | CYS471 |
| B | CYS475 |
| B | CYS478 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19151156, ECO:0000269|PubMed:25831490, ECO:0007744|PDB:2V1X, ECO:0007744|PDB:2WWY, ECO:0007744|PDB:4U7D |
| Chain | Residue | Details |
| A | CYS453 | |
| A | CYS471 | |
| A | CYS475 | |
| A | CYS478 | |
| B | CYS453 | |
| B | CYS471 | |
| B | CYS475 | |
| B | CYS478 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| A | LYS514 | |
| A | LYS522 | |
| B | LYS514 | |
| B | LYS522 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | GLU601 | |
| B | GLU601 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q6AYJ1 |
| Chain | Residue | Details |
| A | CYS606 | |
| B | CYS606 |
