6SH2
| Crystal structure of human neprilysin E584D in complex with C-type natriuretic peptide. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C-type natriuretic peptide fragment (CNP), CHLORIDE ION, ... | Authors: | Moss, S, Subramanian, V, Acharya, K.R. | Deposit date: | 2019-08-05 | Release date: | 2019-09-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of peptide-bound neprilysin reveals key binding interactions. Febs Lett., 594, 2020
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6SH1
| Crystal structure of substrate-free human neprilysin E584D. | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Neprilysin, ... | Authors: | Moss, S, Subramanian, V, Acharya, K.R. | Deposit date: | 2019-08-05 | Release date: | 2019-09-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of peptide-bound neprilysin reveals key binding interactions. Febs Lett., 594, 2020
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6GID
| High resolution crystal structure of substrate-free human neprilysin | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | Authors: | Moss, S, Subramanian, V, Acharya, K.R. | Deposit date: | 2018-05-10 | Release date: | 2018-06-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High resolution crystal structure of substrate-free human neprilysin. J. Struct. Biol., 204, 2018
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1GNU
| GABA(A) receptor associated protein GABARAP | Descriptor: | GABARAP, NICKEL (II) ION | Authors: | Knight, D, Harris, R, Moss, S, Driscoll, P.C, Keep, N.H. | Deposit date: | 2001-10-09 | Release date: | 2001-12-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The X-Ray Crystal Structure and Putative Ligand-Derived Peptide Binding Properties of Gamma-Aminobutyric Acid Receptor Type a Receptor-Associated Protein J.Biol.Chem., 277, 2002
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8OXG
| Crystal structure of human methionine aminopeptidase-2 complexed with (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl N-(trans-4-aminocyclohexyl)carbamate | Descriptor: | MANGANESE (II) ION, Methionine aminopeptidase 2, [(1~{R},2~{S},3~{S},4~{R})-2-methoxy-4-methyl-3-[(2~{R},3~{S})-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-4-oxidanyl-cyclohexyl] ~{N}-(4-azanylcyclohexyl)carbamate | Authors: | Moss, S, Cornelius, P. | Deposit date: | 2023-05-02 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.731 Å) | Cite: | Pharmacological Characterization of SDX-7320/Evexomostat: a Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-Tumor and Anti-Metastatic Activity. Mol.Cancer Ther., 2024
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7Z9P
| The novel DNA binding mechanism of ridinilazole, a precision Clostridiodes difficile antibiotic | Descriptor: | DNA (5'-D(P*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G*(RID))-3'), Ridinilazole, SODIUM ION, ... | Authors: | Mason, S, Leonard, P.M. | Deposit date: | 2022-03-21 | Release date: | 2023-03-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic. Antimicrob.Agents Chemother., 67, 2023
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6RU5
| human complement C3 in complex with the hC3Nb1 nanobody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jensen, R.K, Andersen, G.R. | Deposit date: | 2019-05-27 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6RU3
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6RUR
| Structure of the SCIN stabilized C3bBb convertase bound to properdin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, ... | Authors: | Pedersen, D.V, Gadeberg, T.A.F, Andersen, G.R. | Deposit date: | 2019-05-29 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (6 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6RUS
| Structure of a functional properdin monomer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, SULFATE ION, ... | Authors: | Pedersen, D.V, Andersen, G.R. | Deposit date: | 2019-05-29 | Release date: | 2019-08-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6RUV
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6RV6
| Structure of properdin lacking TSR3 based on anomalous data | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, alpha-D-mannopyranose, ... | Authors: | Pedersen, D.V, Andersen, G.R. | Deposit date: | 2019-05-31 | Release date: | 2019-08-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.507 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6SEJ
| Structure of a functional monomeric properdin lacking TSR3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, alpha-D-mannopyranose, ... | Authors: | Pedersen, D.V, Andersen, G.R. | Deposit date: | 2019-07-30 | Release date: | 2019-08-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.501 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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