6RU5

human complement C3 in complex with the hC3Nb1 nanobody

Summary for 6RU5

• Entry DOI: 10.2210/pdb6ru5/pdb
• Descriptor: Complement C3, hC3Nb1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: innate immunity, complement c3, antibody, nanobody, immune system
• Biological source: Lama glama (llama); More
• Total number of polymer chains: 3
• Total formula weight: 200040.14

Authors

Jensen, R.K.,Andersen, G.R. (deposition date: 2019-05-27, release date: 2019-08-21, Last modification date: 2024-01-24)

• Primary citation: Pedersen, D.V.,Gadeberg, T.A.F.,Thomas, C.,Wang, Y.,Joram, N.,Jensen, R.K.,Mazarakis, S.M.M.,Revel, M.,El Sissy, C.,Petersen, S.V.,Lindorff-Larsen, K.,Thiel, S.,Laursen, N.S.,Fremeaux-Bacchi, V.,Andersen, G.R.; Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.; Front Immunol, 10:2007-2007, 2019; PubMed: 31507604; DOI: 10.3389/fimmu.2019.02007

Experimental method

X-RAY DIFFRACTION (3.9 Å)