6RU5
human complement C3 in complex with the hC3Nb1 nanobody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Complement C3 | polymer | 645 | 71392.3 | 1 | UniProt (P01024) Pfam (PF17790) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) | Homo sapiens (Human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| 2 | B (B) | Complement C3 | polymer | 992 | 113169.9 | 1 | UniProt (P01024) Pfam (PF21308) Pfam (PF07677) Pfam (PF01759) Pfam (PF01821) Pfam (PF00207) Pfam (PF21406) Pfam (PF07678) | Homo sapiens (Human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| 3 | C (C) | hC3Nb1 | polymer | 130 | 14345.9 | 1 | Lama glama (llama) | ||
| 4 | D (D) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 5 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A: 23 - 667 (UniProt: P01024)
| PDB | External Database | Details |
|---|---|---|
| Gln 435 | Glu 435 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 198908.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 910.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 200040.1 |
