6SEJ

Structure of a functional monomeric properdin lacking TSR3

Summary for 6SEJ

• Entry DOI: 10.2210/pdb6sej/pdb
• Descriptor: Properdin, beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: innate immunity, complement, protease, regulator, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 47072.37

Authors

Pedersen, D.V.,Andersen, G.R. (deposition date: 2019-07-30, release date: 2019-08-21, Last modification date: 2020-07-29)

• Primary citation: Pedersen, D.V.,Gadeberg, T.A.F.,Thomas, C.,Wang, Y.,Joram, N.,Jensen, R.K.,Mazarakis, S.M.M.,Revel, M.,El Sissy, C.,Petersen, S.V.,Lindorff-Larsen, K.,Thiel, S.,Laursen, N.S.,Fremeaux-Bacchi, V.,Andersen, G.R.; Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.; Front Immunol, 10:2007-2007, 2019; PubMed: 31507604; DOI: 10.3389/fimmu.2019.02007

Experimental method

X-RAY DIFFRACTION (3.501 Å)