6SEJ

Structure of a functional monomeric properdin lacking TSR3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Properdin	polymer	170	18636.9	1	UniProt (P27918) Pfam (PF18487) Pfam (PF00090) In PDB	Homo sapiens (Human)	Complement factor P
2	B	Properdin	polymer	221	24724.1	1	UniProt (P27918) Pfam (PF00090) In PDB	Homo sapiens (Human)	Complement factor P
3	C, D, E	beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose	branched		326.3	3	In PDB GlyTouCan (G36855WW)
4	F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
5	A, B	alpha-D-mannopyranose	non-polymer		180.2	12	Chemie (MAN)

Sequence modifications

A: 28 - 191 (UniProt: P27918)

PDB	External Database	Details
Glu 192	-	expression tag
Asn 193	-	expression tag
Leu 194	-	expression tag
Tyr 195	-	expression tag
Phe 196	-	expression tag
Gln 197	-	expression tag

B: 256 - 469 (UniProt: P27918)

PDB	External Database	Details
Gly 255	-	expression tag
Glu 470	-	expression tag
Asn 471	-	expression tag
Leu 472	-	expression tag
Tyr 473	-	expression tag
Phe 474	-	expression tag
Gln 475	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43361.1
Branched	Number of molecules	4
	Total formula weight	1549.4
Non-Polymers*	Number of molecules	12
	Total formula weight	2161.9
All*	Total formula weight	47072.4

*Water molecules are not included.