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1J8Y
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BU of 1j8y by Molmil
Signal Recognition Particle conserved GTPase domain from A. ambivalens T112A mutant
Descriptor: SIGNAL RECOGNITION 54 KDA PROTEIN
Authors:Montoya, G, te Kaat, K, Moll, R, Schaerfer, G, Sinning, I.
Deposit date:2001-05-23
Release date:2001-06-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the conserved GTPase of SRP54 from the archaeon Acidianus ambivalens and its comparison with related structures suggests a model for the SRP-SRP receptor complex.
Structure Fold.Des., 8, 2000
1FTS
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BU of 1fts by Molmil
SIGNAL RECOGNITION PARTICLE RECEPTOR FROM E. COLI
Descriptor: FTSY
Authors:Montoya, G, Svensson, C, Luirink, J, Sinning, I.
Deposit date:1996-11-20
Release date:1998-05-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the NG domain from the signal-recognition particle receptor FtsY.
Nature, 385, 1997
1J8M
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BU of 1j8m by Molmil
Signal Recognition Particle conserved GTPase domain from A. ambivalens
Descriptor: SIGNAL RECOGNITION 54 KDA PROTEIN
Authors:Montoya, G, te Kaat, K, Moll, R, Schafer, G, Sinning, I.
Deposit date:2001-05-22
Release date:2001-06-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the conserved GTPase of SRP54 from the archaeon Acidianus ambivalens and its comparison with related structures suggests a model for the SRP-SRP receptor complex.
Structure Fold.Des., 8, 2000
4ZTD
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BU of 4ztd by Molmil
Crystal Structure of Human PCNA in complex with a TRAIP peptide
Descriptor: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen
Authors:Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A.
Deposit date:2015-05-14
Release date:2015-12-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212, 2016
5MGA
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BU of 5mga by Molmil
Structure of the Cpf1 endonuclease R-loop complex after DNA cleavage
Descriptor: CRISPR-associated endonuclease Cpf1, DNA (26-MER), DNA (5'-D(P*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*GP*T)-3'), ...
Authors:Montoya, G, Stella, S.
Deposit date:2016-11-21
Release date:2017-06-21
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage.
Nature, 546, 2017
6GTE
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BU of 6gte by Molmil
Transient state structure of CRISPR-Cpf1 (Cas12a) I3 conformation
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*G)-3'), ...
Authors:Montoya, G, Mesa, P, Stella, S.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
6GTF
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BU of 6gtf by Molmil
Transient state structure of CRISPR-Cpf1 (Cas12a) I5 conformation
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*A)-3'), ...
Authors:Montoya, G, Mesa, P, Stella, S.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
6GTD
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BU of 6gtd by Molmil
Transient state structure of CRISPR-Cpf1 (Cas12a) I2 conformation
Descriptor: CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*GP*T)-3'), DNA (5'-D(P*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ...
Authors:Montoya, G, Mesa, P.
Deposit date:2018-06-18
Release date:2018-12-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
5JNO
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BU of 5jno by Molmil
Crystal structure of the BD1-NTPR complex from BEND3 and PICH
Descriptor: BEN domain-containing protein 3, DNA excision repair protein ERCC-6-like, GLYCEROL
Authors:Pitchai, G, Mesa, P, Hickson, I.D, Montoya, G.
Deposit date:2016-04-30
Release date:2017-09-13
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the BD1-NTPR complex from BEND3 and PICH
To Be Published
4UT0
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BU of 4ut0 by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 10 DAYS INCUBATION IN 5MM MN (STATE 7)
Descriptor: 5'-D(*CP*CP*GP*GP*CP*AP*AP*GP*GP*CP)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*CP)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', ...
Authors:Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G.
Deposit date:2014-07-17
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
8BF8
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BU of 8bf8 by Molmil
ISDra2 TnpB in complex with reRNA
Descriptor: Deinococcus radiodurans R1 chromosome 1, RNA-guided DNA endonuclease TnpB
Authors:Sasnauskas, G, Tamulaitiene, G, Carabias, A, Siksnys, V, Montoya, G, Druteika, G, Silanskas, A, Venclovas, C, Karvelis, T, Kazlauskas, D.
Deposit date:2022-10-24
Release date:2023-04-12
Last modified:2023-04-26
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
8EXA
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BU of 8exa by Molmil
ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 1 (RuvC domain resolved)
Descriptor: DNA (43-MER), RNA (150-MER), RNA-guided DNA endonuclease TnpB
Authors:Sasnauskas, G, Tamulaitiene, G, Carabias, A, Karvelis, T, Druteika, G, Silanskas, A, Montoya, G, Venclovas, C, Kazlauskas, D, Siksnys, V.
Deposit date:2022-10-25
Release date:2023-04-05
Last modified:2023-04-26
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
8EX9
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BU of 8ex9 by Molmil
ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 2 (RuvC domain unresolved)
Descriptor: DNA (43-MER), RNA (150-MER), RNA-guided DNA endonuclease TnpB
Authors:Sasnauskas, G, Tamulaitiene, G, Carabias, A, Karvelis, T, Druteika, G, Silanskas, A, Montoya, G, Venclovas, C, Kazlauskas, D, Siksnys, V.
Deposit date:2022-10-25
Release date:2023-04-05
Last modified:2023-04-26
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:TnpB structure reveals minimal functional core of Cas12 nuclease family.
Nature, 616, 2023
3BZI
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BU of 3bzi by Molmil
Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization
Descriptor: 9 mer peptide from M-phase inducer phosphatase 3, FORMIC ACID, Serine/threonine-protein kinase PLK1
Authors:Garcia-Alvarez, B, de Carcer, G, Ibanez, S, Bragado-Nilsson, E, Montoya, G.
Deposit date:2008-01-18
Release date:2008-02-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2XSM
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BU of 2xsm by Molmil
Crystal structure of the mammalian cytosolic chaperonin CCT in complex with tubulin
Descriptor: CCT
Authors:Munoz, I.G, Yebenes, H, Zhou, M, Mesa, P, Serna, M, Bragado-Nilsson, E, Beloso, A, Robinson, C.V, Valpuesta, J.M, Montoya, G.
Deposit date:2010-10-29
Release date:2010-12-15
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Crystal Structure of the Open Conformation of the Mammalian Chaperonin Cct in Complex with Tubulin.
Nat.Struct.Mol.Biol., 18, 2011
7Z37
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BU of 7z37 by Molmil
Structure of the RAF1-HSP90-CDC37 complex (RHC-II)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
Authors:Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G.
Deposit date:2022-03-01
Release date:2022-09-14
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation.
Mol.Cell, 82, 2022
7Z38
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BU of 7z38 by Molmil
Structure of the RAF1-HSP90-CDC37 complex (RHC-I)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ...
Authors:Mesa, P, Garcia-Alonso, S, Barbacid, M, Montoya, G.
Deposit date:2022-03-01
Release date:2022-09-14
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation.
Mol.Cell, 82, 2022
2XE0
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BU of 2xe0 by Molmil
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Descriptor: 24MER DNA, ACETATE ION, I-CREI V2V3 VARIANT, ...
Authors:Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Redondo, P, Villate, M, Merino, N, Marenchino, M, D'Abramo, M, Gervasio, F.L, Grizot, S, Daboussi, F, Smith, J, Chion-Sotine, I, Paques, F, Duchateau, P, Alibes, A, Stricher, F, Serrano, L, Blanco, F.J, Montoya, G.
Deposit date:2010-05-10
Release date:2010-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Molecular Basis of Engineered Meganuclease Targeting of the Endogenous Human Rag1 Locus
Nucleic Acids Res., 39, 2011
4UNB
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BU of 4unb by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 6 DAYS INCUBATION IN 5MM MN (STATE 5)
Descriptor: 5'-D(*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*A)-3', ...
Authors:Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UN8
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BU of 4un8 by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2)
Descriptor: 25MER, HOMING ENDONUCLEASE I-DMOI, MANGANESE (II) ION
Authors:Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UN9
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BU of 4un9 by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 8H INCUBATION IN 5MM MN (STATE 3)
Descriptor: 25MER, HOMING ENDONUCLEASE I-DMOI, MANGANESE (II) ION
Authors:Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G.
Deposit date:2014-05-26
Release date:2015-01-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.734 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UN7
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BU of 4un7 by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA BEFORE INCUBATION IN 5MM MN (STATE 1)
Descriptor: 25MER, HOMING ENDONUCLEASE I-DMOI, ZINC ION
Authors:Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UNC
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BU of 4unc by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 8 DAYS INCUBATION IN 5MM MN (STATE 6)
Descriptor: 5'-D(*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*A)-3', ...
Authors:Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4UNA
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BU of 4una by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 2 DAYS INCUBATION IN 5MM MN (STATE 4)
Descriptor: 25MER, 5'-D(*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', ...
Authors:Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G.
Deposit date:2014-05-26
Release date:2014-12-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
2YPF
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BU of 2ypf by Molmil
Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism
Descriptor: 5'-D(*TP*AP*GP*AP*GP*GP*GP*TP*TP*AP*GP*GP*TP*TP *TP*AP*TP*AP*TP*AP*AP)-3', 5'-D(*TP*TP*TP*AP*TP*AP*TP*AP*AP*AP*CP*CP*TP*AP *AP*CP*CP*CP*TP*CP*TP*AP)-3', AVRBS3
Authors:Stella, S, Molina, R, Yefimenko, I, Prieto, J, Silva, G.H, Bertonati, C, Juillerat, A, Duchateau, P, Montoya, G.
Deposit date:2012-10-30
Release date:2013-08-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of the Avrbs3-DNA Complex Provides New Insights Into the Initial Thymine-Recognition Mechanism
Acta Crystallogr.,Sect.D, 69, 2013

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