Author results

4LQ6
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CRYSTAL STRUCTURE OF RV3717 REVEALS A NOVEL AMIDASE FROM M. TUBERCULOSIS
Descriptor:N-acetymuramyl-L-alanine amidase-related protein, ZINC ION, SULFATE ION, ...
Authors:Kumar, A., Kumar, S., Kumar, D., Mishra, A., Dewangan, R.P., Shrivastava, P., Ramachandran, S., Taneja, B.
Deposit date:2013-07-17
Release date:2013-12-04
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 69, 2013
6IEM
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ARGININOSUCCINATE LYASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Argininosuccinate lyase, GLYCEROL, 1,2-ETHANEDIOL, ...
Authors:Paul, A., Mishra, A., Surolia, A., Vijayan, M.
Deposit date:2018-09-14
Release date:2019-02-20
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural studies on M. tuberculosis argininosuccinate lyase and its liganded complex: Insights into catalytic mechanism.
IUBMB Life, 71, 2019
6IEN
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SUBSTRATE/PRODUCT BOUND ARGININOSUCCINATE LYASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Argininosuccinate lyase, ARGININOSUCCINATE, FUMARIC ACID, ...
Authors:Paul, A., Mishra, A., Surolia, A., Vijayan, M.
Deposit date:2018-09-14
Release date:2019-02-20
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies on M. tuberculosis argininosuccinate lyase and its liganded complex: Insights into catalytic mechanism.
IUBMB Life, 71, 2019
2HV8
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CRYSTAL STRUCTURE OF GTP-BOUND RAB11 IN COMPLEX WITH FIP3
Descriptor:Ras-related protein Rab-11A, Rab11 family-interacting protein 3, MAGNESIUM ION, ...
Authors:Eathiraj, S., Mishra, A., Prekeris, R., Lambright, D.G.
Deposit date:2006-07-27
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural Basis for Rab11-mediated Recruitment of FIP3 to Recycling Endosomes.
J.Mol.Biol., 364, 2006
3MJH
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CRYSTAL STRUCTURE OF HUMAN RAB5A IN COMPLEX WITH THE C2H2 ZINC FINGER OF EEA1
Descriptor:Ras-related protein Rab-5A, Early endosome antigen 1, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Mishra, A.K., Eathiraj, S., Lambright, D.G.
Deposit date:2010-04-12
Release date:2010-05-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1).
Proc.Natl.Acad.Sci.USA, 107, 2010
3QDH
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CRYSTAL STRUCTURE OF ACTINOMYCES FIMBRIAL ADHESIN FIMA
Descriptor:Fimbrial structural subunit, ZINC ION
Authors:Devarajan, B., Krishnan, V., Narayana, S.V.L.
Deposit date:2011-01-18
Release date:2011-08-24
Last modified:2011-09-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development.
Mol.Microbiol., 81, 2011
3SNY
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CRYSTAL STRUCTURE OF A MUTANT T82R OF A BETAGAMMA-CRYSTALLIN DOMAIN FROM CLOSTRIDIUM BEIJERINCKII
Descriptor:Clostrillin, CALCIUM ION, SULFATE ION
Authors:Srivastava, S.S., Sankaranarayanan, R.
Deposit date:2011-06-29
Release date:2011-11-16
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Decoding the molecular design principles underlying Ca(2+) binding to beta gamma-crystallin motifs
J.Mol.Biol., 415, 2012
3SNZ
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CRYSTAL STRUCTURE OF A MUTANT W39D OF A BETAGAMMA-CRYSTALLIN DOMAIN FROM CLOSTRIDIUM BEIJERINCKII
Descriptor:Clostrillin, CALCIUM ION
Authors:Srivastava, S.S., Sankaranarayanan, R.
Deposit date:2011-06-29
Release date:2011-11-16
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Decoding the molecular design principles underlying Ca(2+) binding to beta gamma-crystallin motifs
J.Mol.Biol., 415, 2012
3SO0
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CRYSTAL STRUCTURE OF A MUTANT T41S OF A BETAGAMMA-CRYSTALLIN DOMAIN FROM CLOSTRIDIUM BEIJERINCKII
Descriptor:Clostrillin, CALCIUM ION
Authors:Srivastava, S.S., Sankaranarayanan, R.
Deposit date:2011-06-29
Release date:2011-11-16
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Decoding the molecular design principles underlying Ca(2+) binding to beta gamma-crystallin motifs
J.Mol.Biol., 415, 2012
3SO1
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CRYSTAL STRUCTURE OF A DOUBLE MUTANT T41S T82S OF A BETAGAMMA-CRYSTALLIN DOMAIN FROM CLOSTRIDIUM BEIJERINCKII
Descriptor:Clostrillin, CALCIUM ION, SULFATE ION
Authors:Srivastava, S.S., Sankaranarayanan, R.
Deposit date:2011-06-29
Release date:2011-11-16
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Decoding the molecular design principles underlying Ca(2+) binding to beta gamma-crystallin motifs
J.Mol.Biol., 415, 2012
5XI1
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STRUCTURAL INSIGHT OF FLAVONOIDS BINDING TO CAG REPEAT RNA THAT CAUSES HUNTINGTON'S DISEASE (HD) AND SPINOCEREBELLAR ATAXIA (SCAS)
Descriptor:RNA (5'-R(P*CP*CP*GP*CP*AP*GP*CP*GP*G)-3'), 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE
Authors:Tawani, A., Mishra, S.K., Khan, E., Kumar, A.
Deposit date:2017-04-25
Release date:2018-08-08
Method:SOLUTION NMR
Cite:Myricetin Reduces Toxic Level of CAG Repeats RNA in Huntington's Disease (HD) and Spino Cerebellar Ataxia (SCAs).
ACS Chem. Biol., 13, 2018
6HHO
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CRYSTAL STRUCTURE OF RIP1 KINASE IN COMPLEX WITH GSK547
Descriptor:Receptor-interacting serine/threonine-protein kinase 1, 6-[4-[(5~{S})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]carbonylpiperidin-1-yl]pyrimidine-4-carbonitrile
Authors:Thorpe, J.H., Harris, P.A.
Deposit date:2018-08-28
Release date:2018-12-12
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Cancer Cell, 34, 2018
2WD5
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SMC HINGE HETERODIMER (MOUSE)
Descriptor:STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1A, STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3
Authors:Michie, K.A., Haering, C.H., Nasmyth, K., Lowe, J.
Deposit date:2009-03-20
Release date:2010-08-11
Last modified:2012-10-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Positively Charged Channel within the Smc1/Smc3 Hinge Required for Sister Chromatid Cohesion.
Embo J., 30, 2011
3TVY
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STRUCTURAL ANALYSIS OF ADHESIVE TIP PILIN, GBS104 FROM GROUP B STREPTOCOCCUS AGALACTIAE
Descriptor:Cell wall surface anchor family protein, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION
Authors:Krishnan, V., Narayana, S.V.L.
Deposit date:2011-09-21
Release date:2013-03-27
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions.
Acta Crystallogr.,Sect.D, 69, 2013
3TW0
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STRUCTURAL ANALYSIS OF ADHESIVE TIP PILIN, GBS104 FROM GROUP B STREPTOCOCCUS AGALACTIAE
Descriptor:Cell wall surface anchor family protein, MAGNESIUM ION, ACETATE ION
Authors:Krishnan, V., Narayana, S.V.L.
Deposit date:2011-09-21
Release date:2013-03-27
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions.
Acta Crystallogr.,Sect.D, 69, 2013
3TXA
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STRUCTURAL ANALYSIS OF ADHESIVE TIP PILIN, GBS104 FROM GROUP B STREPTOCOCCUS AGALACTIAE
Descriptor:Cell wall surface anchor family protein, MAGNESIUM ION, CADMIUM ION, ...
Authors:Krishnan, V., Narayana, S.V.L.
Deposit date:2011-09-23
Release date:2013-03-27
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.619 Å)
Cite:Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions.
Acta Crystallogr.,Sect.D, 69, 2013
4K4E
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CO-CRYSTAL STRUCTURE OF TNKS1 WITH COMPOUND 52 [N~2-(5-CHLORO-2-METHOXYPHENYL)-N-[TRANS-4-(2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-1-YL)CYCLOHEXYL]GLYCINAMIDE]
Descriptor:Tankyrase-1, ZINC ION, N~2~-(5-chloro-2-methoxyphenyl)-N-[trans-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)cyclohexyl]glycinamide
Authors:Huang, X.
Deposit date:2013-04-12
Release date:2013-06-05
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
4K4F
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CO-CRYSTAL STRUCTURE OF TNKS1 WITH COMPOUND 18 [4-[(4S)-5,5-DIMETHYL-2-OXO-4-PHENYL-1,3-OXAZOLIDIN-3-YL]-N-(QUINOLIN-8-YL)BENZAMIDE]
Descriptor:Tankyrase-1, ZINC ION, 4-[(4S)-5,5-dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-N-(quinolin-8-yl)benzamide
Authors:Huang, X., Bregman, H., Wilson, C., DiMauro, E., Gunaydin, H.
Deposit date:2013-04-12
Release date:2013-06-05
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
4MSG
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CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 22
Descriptor:Tankyrase-1, ZINC ION, 3-[(4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]-N-[trans-4-(5-phenyl-1,3,4-oxadiazol-2-yl)cyclohexyl]propanamide
Authors:Huang, X.
Deposit date:2013-09-18
Release date:2013-12-25
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
4MSK
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CO-CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 34
Descriptor:Tankyrase-1, ZINC ION, 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]propanamide
Authors:Huang, X.
Deposit date:2013-09-18
Release date:2013-12-25
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
4MT9
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CO-CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 49
Descriptor:Tankyrase-1, ZINC ION, N-[trans-4-(4-cyanophenoxy)cyclohexyl]-3-[(4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]propanamide
Authors:Huang, X.
Deposit date:2013-09-19
Release date:2013-12-25
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
3ENT
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CRYSTAL STRUCTURE OF NITROLLIN, A BETAGAMMA-CRYSTALLIN FROM NITROSOSPIRA MULTIFORMIS-IN ALTERNATE SPACE GROUP (P65)
Descriptor:Putative uncharacterized protein
Authors:Aravind, P., Sankaranarayanan, R.
Deposit date:2008-09-26
Release date:2009-03-31
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Three-dimensional domain swapping in nitrollin, a single-domain betagamma-crystallin from Nitrosospira multiformis, controls protein conformation and stability but not dimerization
J.Mol.Biol., 385, 2009
3ENU
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CRYSTAL STRUCTURE OF NITROLLIN, A BETAGAMMA-CRYSTALLIN FROM NITROSOSPIRA MULTIFORMIS
Descriptor:Putative uncharacterized protein
Authors:Aravind, P., Sankaranarayanan, R.
Deposit date:2008-09-26
Release date:2009-03-31
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Three-dimensional domain swapping in nitrollin, a single-domain betagamma-crystallin from Nitrosospira multiformis, controls protein conformation and stability but not dimerization
J.Mol.Biol., 385, 2009
3HZ2
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CRYSTAL STRUCTURE OF A BETAGAMMA-CRYSTALLIN FROM AN ARCHAEA
Descriptor:Beta/gama crystallin family protein, CALCIUM ION
Authors:Aravind, P., Sankaranarayanan, R.
Deposit date:2009-06-23
Release date:2009-12-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The betagamma-crystallin superfamily contains a universal motif for binding calcium
Biochemistry, 48, 2009
3HZB
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CRYSTAL STRUCTURE OF A BETAGAMMA-CRYSTALLIN DOMAIN FROM FLAVOBACTERIUM JOHNSONIAE
Descriptor:Carbohydrate binding protein, CALCIUM ION
Authors:Aravind, P., Sankaranarayanan, R.
Deposit date:2009-06-23
Release date:2009-12-01
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The betagamma-crystallin superfamily contains a universal motif for binding calcium
Biochemistry, 48, 2009
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