6YG9

CRYSTAL STRUCTURE OF HUMAN SERUM ALBUMIN (HSA) IN COMPLEX WITH GN-07.

Summary for 6YG9

• Entry DOI: 10.2210/pdb6yg9/pdb
• Related: 6yau
• Descriptor: Serum albumin, MYRISTIC ACID, 20-[[(2~{S})-5-[2-[2-[2-[2-[2-[2-(diethylamino)-2-oxidanylidene-ethoxy]ethoxy]ethylamino]-2-oxidanylidene-ethoxy]ethoxy]ethylamino]-1-oxidanyl-1,5-bis(oxidanylidene)pentan-2-yl]amino]-20-oxidanylidene-icosanoic acid, ... (4 entities in total)
• Functional Keywords: drug transport, fatty acid binding, liver imaging, nash, human serum albumin, transport protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 68758.51

Authors

Schreuder, H.A.,Liesum, A. (deposition date: 2020-03-27, release date: 2021-01-13)

• Primary citation: Mishra, A.,Castaneda, T.R.,Bader, E.,Elshorst, B.,Cummings, S.,Scherer, P.,Bangari, D.S.,Loewe, C.,Schreuder, H.,Poverlein, C.,Helms, M.,Jones, S.,Zech, G.,Licher, T.,Wagner, M.,Schudok, M.,de Hoop, M.,Plowright, A.T.,Atzrodt, J.,Kannt, A.,Laitinen, I.,Derdau, V.; Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis.; Adv Sci, 7:2002997-2002997, 2020; PubMed: 33344141; DOI: 10.1002/advs.202002997

Experimental method

X-RAY DIFFRACTION (1.89 Å)