6YAU

CRYSTAL STRUCTURE OF ASGPR 1 IN COMPLEX WITH GN-A.

Summary for 6YAU

Entry DOI	10.2210/pdb6yau/pdb
Descriptor	Asialoglycoprotein receptor 1, CALCIUM ION, 5-[(2~{R},3~{R},4~{R},5~{R},6~{R})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-~{N}-[3-(propanoylamino)propyl]pentanamide, ... (4 entities in total)
Functional Keywords	asialog glycoprotein receptor, liver imaging, nash, sugar binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	18538.31
Authors	Schreuder, H.A.,Liesum, A. (deposition date: 2020-03-13, release date: 2021-01-13, Last modification date: 2024-01-24)
Primary citation	Mishra, A.,Castaneda, T.R.,Bader, E.,Elshorst, B.,Cummings, S.,Scherer, P.,Bangari, D.S.,Loewe, C.,Schreuder, H.,Poverlein, C.,Helms, M.,Jones, S.,Zech, G.,Licher, T.,Wagner, M.,Schudok, M.,de Hoop, M.,Plowright, A.T.,Atzrodt, J.,Kannt, A.,Laitinen, I.,Derdau, V. Triantennary GalNAc Molecular Imaging Probes for Monitoring Hepatocyte Function in a Rat Model of Nonalcoholic Steatohepatitis. Adv Sci, 7:2002997-2002997, 2020 Cited by PubMed: 33344141 DOI: 10.1002/advs.202002997 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.397 Å)

Structure validation