Author results

5MRX
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27-NT SRL WITH A 5-HYDROXYMETHYL CYTIDINE MODIFICATION
Descriptor:RNA (27-MER)
Authors:Ennifar, E., Micura, R.
Deposit date:2016-12-28
Release date:2018-01-17
Method:X-RAY DIFFRACTION (0.851 Å)
Cite:Xray structure of 5hmrc-modified RNA at atomic resolution
To Be Published
5NQI
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E.COLI 16S RRNA SARCIN-RICIN LOOP CONTAINING A 5-HYDROXYMETHYLCYTOSINE MODIFICATION
Descriptor:E.Coli 27-mer SRL RNA
Authors:Ennifar, E., Micura, R.
Deposit date:2017-04-20
Release date:2017-07-26
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (0.851 Å)
Cite:Synthesis, Thermodynamic Properties, and Crystal Structure of RNA Oligonucleotides Containing 5-Hydroxymethylcytosine.
J. Org. Chem., 82, 2017
3DW5
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CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23S RRNA, U2656-OCH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW4
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CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA, U2650-OCH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA, GLYCEROL
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
5D99
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3DW4 REDETERMINED BY DIRECT METHODS STARTING FROM RANDOM PHASE ANGLES
Descriptor:RNA (27-MER) hairpin from sarcin-ricin domain of E. coli 23S rRNA, GLYCEROL
Authors:Mooers, B.H.M.
Deposit date:2015-08-18
Release date:2016-04-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Direct-methods structure determination of a trypanosome RNA-editing substrate fragment with translational pseudosymmetry
Acta Crystallogr.,Sect.D, 72, 2016
4Y27
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E.COLI 23S SARCIN-RICIL LOOP, MODIFIED WITH A 2-ME ON G2661 AND A METHYLPHOSPHONATE ON A2662
Descriptor:27-mer SRL RNA
Authors:Ennifar, E., Micura, R., Fluer, S.
Deposit date:2015-02-09
Release date:2015-11-18
Method:X-RAY DIFFRACTION (0.998 Å)
Cite:Role of a ribosomal RNA phosphate oxygen during the EF-G-triggered GTP hydrolysis.
Proc.Natl.Acad.Sci.USA, 112, 2015
3DVZ
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CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA, GLYCEROL
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW6
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CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA, U2650-SECH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA, GLYCEROL
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW7
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CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA, U2656-SECH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
4NLF
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2'-TRIFLUOROMETHYLTHIO-2'-DEOXYCYTIDINE-MODIFIED SRL
Descriptor:23S ribosomal RNA Sarcin Ricin Loop, SULFATE ION
Authors:Ennifar, E., Micura, R., Kosutic, M.
Deposit date:2013-11-14
Release date:2014-11-19
Method:X-RAY DIFFRACTION (1 Å)
Cite:2'-Trifluoromethylthio-modified RNA: synthesis, X-ray structure, thermodynamic analysis, and applications
To be Published
4NMG
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2'-TRIFLUOROMETHYLTHIO-2'-DEOXYURIDINE-MODIFIED SRL
Descriptor:23S ribosomal RNA Sarcin Ricin Loop
Authors:Ennifar, E., Micura, R., Kosutic, M.
Deposit date:2013-11-15
Release date:2014-11-19
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:2'-Trifluoromethylthio-modified RNA: synthesis, X-ray structure, thermodynamic analysis, and applications
To be Published
2Q1O
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CRYSTAL STRUCTURE ANALYSIS OF THE RNA DODECAMER CGC-NF2-AAUUGGCG, WITH AN INCORPORATED 2,4-DIFLUOROTOLUYL RESIDUE (NF2)
Descriptor:RNA (5'-R(*CP*GP*CP*(NF2)P*AP*AP*UP*UP*GP*GP*CP*G)-3')
Authors:Li, F., Pallan, P.S.
Deposit date:2007-05-25
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.
Nucleic Acids Res., 35, 2007
3S7C
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CRYSTAL STRUCTURE OF A 2'-AZIDO-URIDINE-MODIFIED RNA
Descriptor:Ecoli 23 S rRNA Sarcin Ricin loop
Authors:Ennifar, E., Micura, R.
Deposit date:2011-05-26
Release date:2012-04-11
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling.
Acs Chem.Biol., 7, 2012
2Q1R
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CRYSTAL STRUCTURE ANALYSIS OF THE RNA DODECAMER CGCGAAUUAGCG, WITH A G-A MISMATCH.
Descriptor:RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*AP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Li, F., Pallan, P.S.
Deposit date:2007-05-25
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.
Nucleic Acids Res., 35, 2007
4NXH
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2'-TRIFLUOROMETHYLTHIOURIDINE-MODIFIED E. COLI 23S RRNA SARCIN RICIN LOOP
Descriptor:23S ribosomal RNA Sarcin Ricin Loop, GLYCEROL, SULFATE ION
Authors:Ennifar, E., Micura, R., Kosutic, M.
Deposit date:2013-12-09
Release date:2014-12-10
Method:X-RAY DIFFRACTION (1.158 Å)
Cite:2'-Trifluoromethylthio-modified RNA: synthesis, X-ray structure, thermodynamic analysis, and applications
To be Published
3S8U
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CRYSTAL STRUCTURE OF A 2-AZIDO-ADENINE-MODIFIED RNA
Descriptor:Ecoli 23 S rRNA Sarcin Ricin loop
Authors:Ennifar, E., Micura, R.
Deposit date:2011-05-31
Release date:2012-04-11
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling.
Acs Chem.Biol., 7, 2012
3C3Z
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CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO RIBOSTAMYCIN
Descriptor:HIV-1 subtype F genomic RNA, RIBOSTAMYCIN
Authors:Freisz, S., Lang, K., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-01-29
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
5VXB
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CRYSTAL STRUCTURE OF CAULOBACTER CRESCENTUS PROXP-ALA AT 1.69 ANGSTROM
Descriptor:ProXp-ala
Authors:Foster, M.P., Musier-Forsyth, K., Nakanishi, K., Ma, X.
Deposit date:2017-05-23
Release date:2017-08-09
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Conformational and chemical selection by a trans-acting editing domain.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3C7R
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CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO NEOMYCIN
Descriptor:HIV-1 subtype F genomic RNA, NEOMYCIN, POTASSIUM ION
Authors:Freisz, S., Lang, K., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-02-08
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
2QEK
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HIV-1 SUBTYPE F DIS RNA EXTENDED DUPLEX FORM
Descriptor:HIV-1 subtype F DIS genomic RNA, POTASSIUM ION, MAGNESIUM ION
Authors:Freisz, S., Ennifar, E., Dumas, P.
Deposit date:2007-06-26
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3C5D
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CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO LIVIDOMYCIN
Descriptor:'HIV-1 subtype F genomic RNA, POTASSIUM ION, (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMETHYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL
Authors:Freisz, S., Lang, K., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-01-31
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3CJZ
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EFFECTS OF N2,N2-DIMETHYLGUANOSINE ON RNA STRUCTURE AND STABILITY: CRYSTAL STRUCTURE OF AN RNA DUPLEX WITH TANDEM M22G:A PAIRS
Descriptor:RNA (5'-R(*GP*GP*AP*CP*GP*(M2G)P*AP*CP*GP*UP*CP*CP*U)-3')
Authors:Pallan, P.S., Kreutz, C., Bosio, S., Micura, R., Egli, M.
Deposit date:2008-03-14
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs.
Rna, 14, 2008
3C44
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CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO PAROMOMYCIN
Descriptor:HIV-1 subtype F genomic RNA, PAROMOMYCIN, POTASSIUM ION, ...
Authors:Freisz, S., Ennifar, E., Dumas, P.
Deposit date:2008-01-29
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3DVV
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CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO RIBOSTAMYCIN (U267OME)
Descriptor:HIV-1 genomic RNA, POTASSIUM ION, CHLORIDE ION, ...
Authors:Ennifar, E., Dumas, P., Olieric, V.
Deposit date:2008-07-21
Release date:2008-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A fast strategy for Selenium derivatization and phasing of RNA structures
To be Published
5Y85
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STRUCTURE-BASED INSIGHTS INTO SELF-CLEAVAGE BY A FOUR-WAY JUNCTIONAL TWISTER-SISTER RIBOZYME
Descriptor:RNA (5'-R(P*AP*CP*CP*CP*GP*CP*AP*AP*GP*GP*CP*CP*GP*AP*CP*GP*GP*C)-3'), DNA/RNA (50-MER), MAGNESIUM ION
Authors:Zheng, L., Micura, R.L., Ren, A.
Deposit date:2017-08-18
Release date:2017-11-22
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Nat Commun, 8, 2017
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