8T8C

Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MFI-tripeptidyl-tRNA analog ACCA-IFMf at 2.60A resolution

This is a non-PDB format compatible entry.

Summary for 8T8C

• Entry DOI: 10.2210/pdb8t8c/pdb
• Descriptor: 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (62 entities in total)
• Functional Keywords: 70s ribosome, peptidyl-trna, rna-peptide conjugate, rna modification, ft-icr mass spectrometry, formylation, ribosome
• Biological source: Escherichia coli K-12; More
• Total number of polymer chains: 112
• Total formula weight: 4431928.26

Authors

Thaler, J.,Syroegin, E.A.,Breuker, K.,Polikanov, Y.S.,Micura, R. (deposition date: 2023-06-22, release date: 2023-07-19, Last modification date: 2023-11-15)

• Primary citation: Thaler, J.,Syroegin, E.A.,Breuker, K.,Polikanov, Y.S.,Micura, R.; Practical Synthesis of N -Formylmethionylated Peptidyl-tRNA Mimics.; Acs Chem.Biol., 18:2233-2239, 2023; PubMed: 37433044; DOI: 10.1021/acschembio.3c00237

Experimental method

X-RAY DIFFRACTION (2.6 Å)