Author results

3UO1
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STRUCTURE OF A MONOCLONAL ANTIBODY COMPLEXED WITH ITS MHC-I ANTIGEN
Descriptor:ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
Authors:Margulies, D.H., Mage, M.G., Wang, R., Natarajan, K.
Deposit date:2011-11-16
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3UYR
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STRUCTURE OF A MONOCLONAL ANTIBODY COMPLEXED WITH ITS MHC-I ANTIGEN
Descriptor:antibody Fab heavy chain, antibody Fab light chain, H-2 class I histocompatibility antigen, ...
Authors:Margulies, D.H., Mage, M.G., Wang, R., Natarajan, K.
Deposit date:2011-12-06
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
3V4U
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STRUCTURE OF A MONOCLONAL ANTIBODY COMPLEXED WITH ITS MHC-I ANTIGEN
Descriptor:ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
Authors:Margulies, D.H., Mage, M.G., Wang, R., Natarajan, K.
Deposit date:2011-12-15
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
1P1Z
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X-RAY CRYSTAL STRUCTURE OF THE LECTIN-LIKE NATURAL KILLER CELL RECEPTOR LY-49C BOUND TO ITS MHC CLASS I LIGAND H-2KB
Descriptor:H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, ...
Authors:Dimasi, N., Natarajan, K., Rangjin, G., Dam, J., Margulies, D.H., Mariuzza, R.A.
Deposit date:2003-04-14
Release date:2003-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).
Nat.Immunol., 4, 2003
1B88
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V-ALPHA 2.6 MOUSE T CELL RECEPTOR (TCR) DOMAIN
Descriptor:T CELL RECEPTOR V-ALPHA DOMAIN
Authors:Plaksin, D., Chacko, S., Navaza, J., Margulies, D.H., Padlan, E.A.
Deposit date:1999-02-09
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The X-ray crystal structure of a Valpha2.6Jalpha38 mouse T cell receptor domain at 2.5 A resolution: alternate modes of dimerization and crystal packing.
J.Mol.Biol., 289, 1999
1DDH
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MHC CLASS I H-2DD HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND AN IMMUNODOMINANT PEPTIDE P18-I10 FROM THE HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120
Descriptor:MHC CLASS I H-2DD HEAVY CHAIN, BETA-2 MICROGLOBULIN, HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120
Authors:Li, H., Margulies, D.H., Mariuzza, R.A.
Deposit date:1998-06-22
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Three-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120.
J.Mol.Biol., 283, 1998
1FM5
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CRYSTAL STRUCTURE OF HUMAN CD69
Descriptor:EARLY ACTIVATION ANTIGEN CD69
Authors:Natarajan, K., Sawicki, M.W., Margulies, D.H., Mariuzza, R.A.
Deposit date:2000-08-16
Release date:2000-12-18
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells.
Biochemistry, 39, 2000
1U58
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CRYSTAL STRUCTURE OF THE MURINE CYTOMEGALOVIRUS MHC-I HOMOLOG M144
Descriptor:MHC-I homolog m144, beta-2-microglobulin
Authors:Natarajan, K., Hicks, A., Robinson, H., Guan, R., Margulies, D.H.
Deposit date:2004-07-27
Release date:2005-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the murine cytomegalovirus MHC-I homolog m144.
J.Mol.Biol., 358, 2006
2MIZ
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STRUCTURE OF THE M04/GP34 MOUSE CYTOMEGALOVIRUS IMMUNOEVASIN CORE DOMAIN
Descriptor:m04 immunoevasin
Authors:Sgourakis, N.G., Natarajan, K., Margulies, D.H., Bax, A.
Deposit date:2013-12-21
Release date:2014-07-16
Last modified:2014-10-22
Method:SOLUTION NMR
Cite:The Structure of Mouse Cytomegalovirus m04 Protein Obtained from Sparse NMR Data Reveals a Conserved Fold of the m02-m06 Viral Immune Modulator Family.
Structure, 22, 2014
2O5N
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CRYSTAL STRUCTURE OF A VIRAL GLYCOPROTEIN
Descriptor:MuHV1gpm153, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Mans, J., Natarajan, K., Robinson, H., Margulies, D.H.
Deposit date:2006-12-06
Release date:2007-09-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Cellular Expression and Crystal Structure of the Murine Cytomegalovirus Major Histocompatibility Complex Class I-like Glycoprotein, m153.
J.Biol.Chem., 282, 2007
3DMM
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CRYSTAL STRUCTURE OF THE CD8 ALPHA BETA/H-2DD COMPLEX
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2 microglobulin, ...
Authors:Wang, R., Natarajan, K., Margulies, D.H.
Deposit date:2008-07-01
Release date:2009-07-14
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position.
J.Immunol., 183, 2009
3E6F
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MHC CLASS I H-2DD HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND A VARIANT PEPTIDE, PA9, FROM THE HUMAN IMMUNODEFICIENCY VIRUS (BAL) ENVELOPE GLYCOPROTEIN 120
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, BETA-2 MICROGLOBULIN, ...
Authors:Wang, R., Natarajan, K., Robinson, H., Margulies, D.H.
Deposit date:2008-08-15
Release date:2009-08-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity
J.Immunol., 183, 2009
3E6H
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MHC CLASS I H-2DD HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND A VARIANT PEPTIDE, PI10, FROM THE HUMAN IMMUNODEFICIENCY VIRUS (BAL) ENVELOPE GLYCOPROTEIN 120
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Putative uncharacterized protein, ...
Authors:Wang, R., Natarajan, K., Robinson, H., Margulies, D.H.
Deposit date:2008-08-15
Release date:2009-08-18
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity
J.Immunol., 183, 2009
3ECB
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CRYSTAL STRUCTURE OF MOUSE H-2DD IN COMPLEX WITH PEPTIDE P18-I10 DERIVED FROM HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2 microglobulin, ...
Authors:Natarajan, K., Wang, R., Margulies, D.H.
Deposit date:2008-08-29
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position
J.Immunol., 183, 2009
3V52
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STRUCTURE OF A MONOCLONAL ANTIBODY COMPLEXED WITH ITS MHC-I ANTIGEN
Descriptor:ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ...
Authors:Mage, M.G., Dolan, M.A., Wang, R., Boyd, L.F., Revilleza, M.J., Robinson, H., Natarajan, K., Myers, N.B., Hansen, T.H., Margulies, D.H.
Deposit date:2011-12-15
Release date:2012-07-25
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (1.697 Å)
Cite:The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics.
J.Immunol., 189, 2012
4G59
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CRYSTAL STRUCTURE OF THE MURINE CYTOMEGALOVIRUS MHC-I HOMOLOG M152 WITH LIGAND RAE-1 GAMMA
Descriptor:Retinoic acid early-inducible protein 1-gamma, M152 protein, N-ACETYL-D-GLUCOSAMINE
Authors:Wang, R., Natarajan, K., Margulies, D.H.
Deposit date:2012-07-17
Release date:2012-12-19
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1gamma reveals a paradigm for MHC/MHC interaction in immune evasion.
Proc.Natl.Acad.Sci.USA, 109, 2012
5WER
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CRYSTAL STRUCTURE OF TAPBPR AND H2-DD COMPLEX
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, ...
Authors:Jiang, J.S., Natarajan, K., Boyd, L.F., Margulies, D.H.
Deposit date:2017-07-10
Release date:2017-10-18
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (3.412 Å)
Cite:Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
5WES
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CRYSTAL STRUCTURE H2-DD WITH DISULFIDE-LINKED 5MER PEPTIDE
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, ...
Authors:Jiang, J.S., Natarajan, K., Boyd, L.F., Margulies, D.H.
Deposit date:2017-07-10
Release date:2017-10-18
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.706 Å)
Cite:Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
5WET
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CRYSTAL STRUCTURE OF H2-DD WITH DISULFIDE-LINKED 6MER PEPTIDE
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, ...
Authors:Jiang, J.S., Natarajan, K., Boyd, L.F., Margulies, D.H.
Deposit date:2017-07-10
Release date:2017-10-18
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
5WEU
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CRYSTAL STRUCTURE OF H2-DD WITH DISULFIDE-LINKED 10MER PEPTIDE
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, ...
Authors:Jiang, J.S., Natarajan, K., Boyd, L.F., Margulies, D.H.
Deposit date:2017-07-10
Release date:2017-10-18
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (1.584 Å)
Cite:Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
Science, 358, 2017
1QO3
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COMPLEX BETWEEN NK CELL RECEPTOR LY49A AND ITS MHC CLASS I LIGAND H-2DD
Descriptor:MHC CLASS I H-2DD HEAVY CHAIN, BETA-2-MICROGLOBULIN, LY49A, ...
Authors:Tormo, J., Mariuzza, R.A.
Deposit date:1999-11-01
Release date:2000-01-02
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of a Lectin-Like Natural Killer Cell Receptor Bound to its Mhc Class I Ligand
Nature, 402, 1999
5IVX
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CRYSTAL STRUCTURE OF B4.2.3 T-CELL RECEPTOR AND H2-DD P18-I10 COMPLEX
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, ...
Authors:Natarajan, K., Jiang, J., Margulies, D.
Deposit date:2016-03-21
Release date:2017-03-29
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.
Nat Commun, 8, 2017
5IW1
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CRYSTAL STRUCTURE OF B4.2.3 T-CELL RECEPTOR
Descriptor:T-CELL RECEPTOR ALPHA CHAIN, T-CELL RECEPTOR BETA CHAIN
Authors:Natarajan, K., Jiang, J., Margulies, D.
Deposit date:2016-03-21
Release date:2017-03-29
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:An allosteric site in the T-cell receptor C beta domain plays a critical signalling role.
Nat Commun, 8, 2017
5KD4
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CRYSTAL STRUCTURE OF MURINE MHC-I H-2DD IN COMPLEX WITH MURINE BETA2-MICROGLOBULIN AND A VARIANT OF PEPTIDE (PVI10) OF HIV GP120 MN ISOLATE (IGPGRAFYVI)
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, ...
Authors:Jiang, J., Natarajan, K., Margulies, D.
Deposit date:2016-06-07
Release date:2017-10-11
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.
J. Immunol., 200, 2018
5KD7
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CRYSTAL STRUCTURE OF MURINE MHC-I H-2DD IN COMPLEX WITH MURINE BETA2-MICROGLOBULIN AND A VARIANT OF PEPTIDE (PV9) OF HIV GP120 MN ISOLATE (IGPGRAFYV)
Descriptor:H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2-microglobulin, ...
Authors:Jiang, J., Natarajan, K., Margulies, D.
Deposit date:2016-06-07
Release date:2017-10-11
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.
J. Immunol., 200, 2018
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