7TUC

Crystal structure of HLA-B*44:05 (T73C) with 9mer EEFGRAFSF

Summary for 7TUC

• Entry DOI: 10.2210/pdb7tuc/pdb
• Related: 7TUD 7TUE 7TUF 7TUG 7TUH
• Descriptor: HLA class I histocompatibility antigen, B alpha chain, Beta-2-microglobulin, MHC class II antigen peptide, ... (6 entities in total)
• Functional Keywords: tapasin, histocompatibility complex class i, mhc-i, hla, peptide editing, peptide loading complex, plc, antigen presentation, immune response, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 45144.07

Authors

Jiang, J.,Natarajan, K.,Kim, E.,Boyd, L.F.,Margulies, D.H. (deposition date: 2022-02-02, release date: 2022-09-07, Last modification date: 2023-10-18)

• Primary citation: Jiang, J.,Taylor, D.K.,Kim, E.J.,Boyd, L.F.,Ahmad, J.,Mage, M.G.,Truong, H.V.,Woodward, C.H.,Sgourakis, N.G.,Cresswell, P.,Margulies, D.H.,Natarajan, K.; Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.; Nat Commun, 13:5470-5470, 2022; PubMed: 36115831; DOI: 10.1038/s41467-022-33153-8

Experimental method

X-RAY DIFFRACTION (1.25 Å)