Author results

6Z8K
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LA CROSSE VIRUS POLYMERASE AT ELONGATION MIMICKING STAGE
Descriptor:La Crosse virus 5' vRNA 1-10, La Crosse virus 5' vRNA (9-16), La Crosse virus 3' vRNA (1-16), ...
Authors:Arragain, B., Effantin, G., Schoehn, G., Cusack, S., Malet, H.
Deposit date:2020-06-02
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
6Z6B
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STRUCTURE OF FULL-LENGTH LA CROSSE VIRUS L PROTEIN (POLYMERASE)
Descriptor:RNA (5'-R(P*AP*GP*UP*AP*GP*UP*GP*UP*GP*C)-3'), RNA (5'-R(P*UP*UP*AP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), RNA (5'-R(*GP*CP*UP*AP*CP*UP*AP*A)-3'), ...
Authors:Cusack, S., Gerlach, P., Reguera, J.
Deposit date:2020-05-28
Release date:2020-07-29
Method:X-RAY DIFFRACTION (3.961 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
6Z6G
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CRYO-EM STRUCTURE OF LA CROSSE VIRUS POLYMERASE AT PRE-INITIATION STAGE
Descriptor:5'vRNA 1-10, 5'vRNA 9-16, 3'vRNA 1-16, ...
Authors:Arragain, B., Effantin, G., Gerlach, P., Reguera, J., Schoehn, G., Cusack, S., Malet, H.
Deposit date:2020-05-28
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
6SZA
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MOXR AAA-ATPASE RAVA, C2-SYMMETRIC CLOSED RING CONFORMATION
Descriptor:RavA, ADENOSINE-5'-DIPHOSPHATE
Authors:Jessop, M., Felix, J., Gutsche, I.
Deposit date:2019-10-02
Release date:2020-02-19
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
6SZB
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MOXR AAA-ATPASE RAVA, SPIRAL OPEN RING CONFORMATION
Descriptor:RavA + Mg-ADP, ADENOSINE-5'-DIPHOSPHATE
Authors:Jessop, M., Felix, J., Gutsche, I.
Deposit date:2019-10-02
Release date:2020-02-19
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
6Q7L
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SPIRAL STRUCTURE OF E. COLI RAVA IN THE RAVA-LDCI CAGE-LIKE COMPLEX
Descriptor:Inducible lysine decarboxylase, ATPase RavA, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Arragain, B., Felix, J., Malet, H., Gutsche, I., Jessop, M.
Deposit date:2018-12-13
Release date:2020-02-12
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
6Q7M
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SPIRAL STRUCTURE OF E. COLI RAVA IN THE RAVA-LDCI CAGE-LIKE COMPLEX
Descriptor:Inducible lysine decarboxylase, ATPase RavA, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Arragain, B., Felix, J., Malet, H., Gutsche, I., Jessop, M.
Deposit date:2018-12-13
Release date:2020-02-12
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Structural insights into ATP hydrolysis by the MoxR ATPase RavA and the LdcI-RavA cage-like complex.
Commun Biol, 3, 2020
6I2N
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HELICAL RNA-BOUND HANTAAN VIRUS NUCLEOCAPSID
Descriptor:RNA (5'-R(P*UP*UP*U)-3'), Nucleoprotein
Authors:Arragain, B., Reguera, J., Desfosses, A., Gutsche, I., Schoehn, G., Malet, H.
Deposit date:2018-11-01
Release date:2019-01-23
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms.
Elife, 8, 2019
6GGS
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STRUCTURE OF RIP2 CARD FILAMENT
Descriptor:Receptor-interacting serine/threonine-protein kinase 2
Authors:Pellegrini, E., Cusack, S., Desfosses, A., Schoehn, G., Malet, H., Gutsche, I., Sachse, C., Hons, M.
Deposit date:2018-05-03
Release date:2018-10-17
Method:ELECTRON MICROSCOPY (3.94 Å)
Cite:RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling.
Nat Commun, 9, 2018
6GFJ
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STRUCTURE OF RIP2 CARD DOMAIN FUSED TO CRYSTALLISABLE MBP TAG
Descriptor:Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Pellegrini, E., Cusack, S.
Deposit date:2018-04-30
Release date:2019-03-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling.
Nat Commun, 9, 2018
5LDF
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MALTOSE BINDING PROTEIN GENETICALLY FUSED TO DODECAMERIC GLUTAMINE SYNTHETASE
Descriptor:Glutamine synthetase, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Coscia, F., Petosa, C., Schoehn, G.
Deposit date:2016-06-25
Release date:2016-08-10
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein.
Sci Rep, 6, 2016
5JCF
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CRYSTAL STRUCTURE OF CHICKEN MDA5 WITH 5'P 10-MER DSRNA AND ADP-MG2+ AT 2.6 A RESOLUTION (ORTHORHOMBIC FORM).
Descriptor:Melanoma differentiation associated protein-5, RNA (5'-R(P*GP*GP*UP*AP*CP*GP*UP*AP*CP*C)-3'), RNA (5'-R(P*AP*GP*GP*UP*AP*CP*GP*UP*AP*CP*C)-3'), ...
Authors:Cusack, S., Uchikawa, E.
Deposit date:2016-04-15
Release date:2016-06-01
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JCH
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CRYSTAL STRUCTURE OF CHICKEN MDA5 WITH 5'P 10-MER DSRNA AND ADP-MG2+ AT 2.95 A RESOLUTION (UNTWINNED).
Descriptor:Melanoma differentiation associated protein-5, RNA (5'-R(P*GP*GP*UP*AP*CP*GP*UP*AP*CP*C)-3'), ZINC ION, ...
Authors:Cusack, S., Uchikawa, E.
Deposit date:2016-04-15
Release date:2016-06-01
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JC3
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CRYSTAL STRUCTURE OF CHICKEN MDA5 WITH 5'P 10-MER DSRNA AND ADP-MG2+ AT 2.6 A RESOLUTION (MONOCLINIC FORM, TWINNED).
Descriptor:Melanoma differentiation associated protein-5, RNA (5'-R(P*GP*GP*UP*AP*CP*GP*UP*AP*CP*C)-3'), ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Cusack, S., Uchikawa, E.
Deposit date:2016-04-14
Release date:2016-06-01
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JC7
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CRYSTAL STRUCTURE OF CHICKEN MDA5 WITH 5'P 24-MER DSRNA AND ADP-MG2+ AT 2.75 A RESOLUTION.
Descriptor:Melanoma differentiation associated protein-5, RNA (5'-R(P*GP*GP*AP*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*GP*UP*CP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*AP*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*GP*UP*CP*CP*C)-3'), ...
Authors:Cusack, S., Uchikawa, E.
Deposit date:2016-04-14
Release date:2016-06-01
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JB2
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CRYSTAL STRUCTURE OF CHICKEN LGP2 WITH 5'PPP 10-MER DSRNA AND ADP-ALF4-MG2+ AT 2.2 A RESOLUTION.
Descriptor:LGP2, RNA (5'-R(*GPPP*GP*UP*AP*CP*GP*UP*AP*CP*CP*C)-3'), RNA (5'-R(*GPPP*GP*UP*AP*CP*GP*UP*AP*CP*C)-3'), ...
Authors:Cusack, S., Uchikawa, E.
Deposit date:2016-04-13
Release date:2016-06-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JBG
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CRYSTAL STRUCTURE OF CHICKEN LGP2 WITH 5'PPP 26-MER HAIRPIN RNA WITH 3' GG OVERHANG AND ADP-ALF4-MG2+ AT 2.0 A RESOLUTION.
Descriptor:LGP2, RNA (5'-R(*GPPP*GP*AP*GP*CP*GP*UP*GP*CP*CP*GP*GP*GP*CP*AP*CP*GP*CP*UP*CP*CP*GP*G)-3'), ZINC ION, ...
Authors:Cusack, S., Uchikawa, E.
Deposit date:2016-04-13
Release date:2016-06-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JBJ
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CRYSTAL STRUCTURE OF CHICKEN LGP2 WITH 5'P 12-MER DSRNA AT 3.6 A RESOLUTION
Descriptor:LGP2, RNA (5'-R(P*GP*GP*UP*AP*GP*CP*GP*CP*UP*AP*CP*C)-3'), ZINC ION
Authors:Cusack, S., Uchikawa, E., Lethier, M.
Deposit date:2016-04-13
Release date:2016-06-01
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5JAJ
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STRUCTURE OF CHICKEN LGP2 WITHA 5'P 10-MER DSRNA AND ADP-ALF4-MG.
Descriptor:LGP2, RNA (5'-R(P*GP*GP*UP*AP*CP*GP*UP*AP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*UP*AP*CP*GP*UP*AP*CP*C)-3'), ...
Authors:Cusack, S., Uchikawa, E.
Deposit date:2016-04-12
Release date:2016-06-01
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Mol.Cell, 62, 2016
5ISN
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NMR SOLUTION STRUCTURE OF MACRO DOMAIN FROM VENEZUELAN EQUINE ENCEPHALITIS VIRUS
Descriptor:Non-structural polyprotein
Authors:Makrynitsa, G.I., Ntonti, D., Marousis, K.D., Tsika, A.C., Papageorgiou, N., Coutard, B., Bentrop, D., Spyroulias, G.A.
Deposit date:2016-03-15
Release date:2017-11-29
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose.
J.Struct.Biol., 206, 2019
5FL2
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REVISITED CRYO-EM STRUCTURE OF INDUCIBLE LYSINE DECARBOXYLASE COMPLEXED WITH LARA DOMAIN OF RAVA ATPASE
Descriptor:LYSINE DECARBOXYLASE, INDUCIBLE, ATPASE RAVA
Authors:Kandiah, E., Carriel, D., Perard, J., Malet, H., Bacia, M., Liu, K., Chan, S.W.S., Houry, W.A., Ollagnier de Choudens, S., Elsen, S., Gutsche, I.
Deposit date:2015-10-21
Release date:2016-09-21
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
5FKX
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STRUCTURE OF E.COLI INDUCIBLE LYSINE DECARBOXYLASE AT ACTIVE PH
Descriptor:LYSINE DECARBOXYLASE, INDUCIBLE
Authors:Kandiah, E., Carriel, D., Perard, J., Malet, H., Bacia, M., Liu, K., Chan, S.W.S., Houry, W.A., Ollagnier de Choudens, S., Elsen, S., Gutsche, I.
Deposit date:2015-10-20
Release date:2016-09-21
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
5FKZ
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STRUCTURE OF E.COLI CONSTITUTIVE LYSINE DECARBOXYLASE
Descriptor:LYSINE DECARBOXYLASE, CONSTITUTIVE
Authors:Kandiah, E., Carriel, D., Perard, J., Malet, H., Bacia, M., Liu, K., Chan, S.W.S., Houry, W.A., Ollagnier de Choudens, S., Elsen, S., Gutsche, I.
Deposit date:2015-10-20
Release date:2016-09-21
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
5AMQ
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STRUCTURE OF THE LA CROSSE BUNYAVIRUS POLYMERASE IN COMPLEX WITH THE 3' AND 5' VIRAL RNA
Descriptor:RNA POLYMERASE L, RNA
Authors:Reguera, J., Gerlach, P., Cusack, S.
Deposit date:2015-03-12
Release date:2015-06-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights Into Bunyavirus Replication and its Regulation by the Vrna Promoter.
Cell, 161, 2015
5AMR
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STRUCTURE OF THE LA CROSSE BUNYAVIRUS POLYMERASE IN COMPLEX WITH THE 3' VIRAL RNA
Descriptor:RNA POLYMERASE L, RNA
Authors:Reguera, J., Gerlach, P., Cusack, S.
Deposit date:2015-03-12
Release date:2015-06-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural Insights Into Bunyavirus Replication and its Regulation by the Vrna Promoter.
Cell(Cambridge,Mass.), 161, 2015
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PDB entries from 2020-08-05