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3R4S
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CELL ENTRY OF BOTULINUM NEUROTOXIN TYPE C IS DEPENDENT UPON INTERACTION WITH TWO GANGLIOSIDE MOLECULES
Descriptor:Botulinum neurotoxin type C1, 5-N-ACETYL-BETA-D-NEURAMINIC ACID, O-SIALIC ACID
Authors:Strotmeier, J., Gu, S., Jutzi, S., Mahrhold, S., Zhou, J., Pich, A., Bigalke, H., Rummel, A., Jin, R., Binz, T.
Deposit date:2011-03-17
Release date:2011-06-08
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
3R4U
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CELL ENTRY OF BOTULINUM NEUROTOXIN TYPE C IS DEPENDENT UPON INTERACTION WITH TWO GANGLIOSIDE MOLECULES
Descriptor:Botulinum neurotoxin type C1
Authors:Strotmeier, J., Gu, S., Jutzi, S., Mahrhold, S., Zhou, J., Pich, A., Bigalke, H., Rummel, A., Jin, R., Binz, T.
Deposit date:2011-03-17
Release date:2011-06-08
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
5JLV
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RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN A IN COMPLEX WITH HUMAN GLYCOSYLATED SV2C
Descriptor:Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C, ACETATE ION, ...
Authors:Yao, G., Zhang, S., Mahrhold, S., Lam, K., Stern, D., Bagramyan, K., Perry, K., Kalkum, M., Rummel, A., Dong, M., Jin, R.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
5JMC
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RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN A IN COMPLEX WITH RAT SV2C
Descriptor:Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
Authors:Yao, G., Zhang, S., Mahrhold, S., Lam, K., Stern, D., Bagramyan, K., Perry, K., Kalkum, M., Rummel, A., Dong, M., Jin, R.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
3OBR
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CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE D BINDING DOMAIN
Descriptor:Botulinum neurotoxin type D, GLYCEROL
Authors:Zong, Y., Lee, K.K., Jin, R.
Deposit date:2010-08-09
Release date:2010-09-08
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
Biochem.J., 431, 2010
3OBT
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CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE D LIGAND BINDING DOMAIN IN COMPLEX WITH N-ACETYLNEURAMINIC ACID
Descriptor:Botulinum neurotoxin type D, 5-N-ACETYL-BETA-D-NEURAMINIC ACID, GLYCEROL
Authors:Lee, K.K., Zong, Y., Jin, R.
Deposit date:2010-08-09
Release date:2010-09-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
Biochem.J., 431, 2010
5BP5
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CRYSTAL STRUCTURE OF HA17-HA33-IPT
Descriptor:HA-33, HA-17, ISOPROPYL-1-BETA-D-THIOGALACTOSIDE
Authors:Lee, K., Lam, K., Jin, R.
Deposit date:2015-05-27
Release date:2015-09-02
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics.
Toxicon, 107, 2015
5BQU
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CRYSTAL STRUCTURE OF HA17-HA33-LACTULOSE
Descriptor:HA-33, HA-17, FRUCTOSE, ...
Authors:Lee, K., Lam, K., Jin, R.
Deposit date:2015-05-29
Release date:2015-10-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics.
Toxicon, 107, 2015