Author results

4PNJ
  • Download 4pnj
  • View 4pnj
Molmil generated image of 4pnj
RECOMBINANT SPERM WHALE P6 MYOGLOBIN SOLVED WITH SINGLE PULSE FREE ELECTRON LASER DATA
Descriptor:Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Cohen, A., Gonzalez, A., Lam, W., Lyubimov, A., Sauter, N., Tsai, Y., Uervirojnangkoorn, M., Brunger, A., Soltis, M.
Deposit date:2014-05-23
Release date:2014-11-05
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Goniometer-based femtosecond crystallography with X-ray free electron lasers.
Proc.Natl.Acad.Sci.USA, 111, 2014
5VNV
  • Download 5vnv
  • View 5vnv
Molmil generated image of 5vnv
CRYSTAL STRUCTURE OF NB.B201
Descriptor:Nb.b201, PENTAETHYLENE GLYCOL, POTASSIUM ION, ...
Authors:Kruse, A.C., McMahon, C.
Deposit date:2017-05-01
Release date:2018-02-21
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Yeast surface display platform for rapid discovery of conformationally selective nanobodies.
Nat. Struct. Mol. Biol., 25, 2018
3HK1
  • Download 3hk1
  • View 3hk1
Molmil generated image of 3hk1
IDENTIFICATION AND CHARACTERIZATION OF A SMALL MOLECULE INHIBITOR OF FATTY ACID BINDING PROTEINS
Descriptor:Fatty acid-binding protein, adipocyte, 4-{[2-(methoxycarbonyl)-5-(2-thienyl)-3-thienyl]amino}-4-oxo-2-butenoic acid
Authors:Hertzel, A.V., Hellberg, K., Reynolds, J.M., Kruse, A.C., Juhlmann, B.E., Smith, A.J., Sanders, M.A., Ohlendorf, D.H., Suttles, J., Bernlohr, D.A.
Deposit date:2009-05-22
Release date:2009-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins.
J.Med.Chem., 52, 2009
3I41
  • Download 3i41
  • View 3i41
Molmil generated image of 3i41
CRYSTAL STRUCTURE OF BETA TOXIN FROM STAPHYLOCOCCUS AUREUS F277A, P278A MUTANT
Descriptor:Beta-hemolysin
Authors:Huseby, M., Shi, K., Kruse, A.C., Ohlendorf, D.H.
Deposit date:2009-07-01
Release date:2010-07-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and biological functions of beta toxin from Staphylococcus aureus: Role of the hydrophobic beta hairpin in virulence
to be published
3I48
  • Download 3i48
  • View 3i48
Molmil generated image of 3i48
CRYSTAL STRUCTURE OF BETA TOXIN FROM STAPHYLOCOCCUS AUREUS F277A, P278A MUTANT WITH BOUND MAGNESIUM IONS
Descriptor:Beta-hemolysin, MAGNESIUM ION, PHOSPHATE ION
Authors:Huseby, M., Shi, K., Kruse, A.C., Ohlendorf, D.H.
Deposit date:2009-07-01
Release date:2010-07-14
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and biological functions of beta toxin from Staphylococcus aureus: Role of the hydrophobic beta hairpin in virulence
to be published, 2009
3JS1
  • Download 3js1
  • View 3js1
Molmil generated image of 3js1
CRYSTAL STRUCTURE OF ADIPOCYTE FATTY ACID BINDING PROTEIN COVALENTLY MODIFIED WITH 4-HYDROXY-2-NONENAL
Descriptor:Adipocyte fatty acid-binding protein, PHOSPHATE ION
Authors:Hellberg, K., Grimsrud, P.A., Kruse, A.C., Banaszak, L.J., Ohlendorf, D.H., Bernlohr, D.A.
Deposit date:2009-09-09
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:X-ray crystallographic analysis of adipocyte fatty acid binding protein (aP2) modified with 4-hydroxy-2-nonenal.
Protein Sci., 19, 2010
3QJH
  • Download 3qjh
  • View 3qjh
Molmil generated image of 3qjh
THE CRYSTAL STRUCTURE OF THE 5C.C7 TCR
Descriptor:5c.c7 alpha chain, 5c.c7 beta chain
Authors:Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C.
Deposit date:2011-01-28
Release date:2011-04-27
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
3TJH
  • Download 3tjh
  • View 3tjh
Molmil generated image of 3tjh
42F3-P3A1/H2-LD COMPLEX
Descriptor:H2-Ld SBM2, p3A1, 42F3 alpha, ...
Authors:Adams, J.J., Kruse, A., Kranz, D.M., Garcia, K.C.
Deposit date:2011-08-24
Release date:2011-12-07
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
3JSQ
  • Download 3jsq
  • View 3jsq
Molmil generated image of 3jsq
CRYSTAL STRUCTURE OF ADIPOCYTE FATTY ACID BINDING PROTEIN NON-COVALENTLY MODIFIED WITH 4-HYDROXY-2-NONENAL
Descriptor:Adipocyte fatty acid-binding protein, CHLORIDE ION, (2E,4R)-4-HYDROXYNON-2-ENAL, ...
Authors:Hellberg, K., Grimsrud, P.A., Kruse, A.C., Banaszak, L.J., Ohlendorf, D.H., Bernlohr, D.A.
Deposit date:2009-09-10
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystallographic analysis of adipocyte fatty acid binding protein (aP2) modified with 4-hydroxy-2-nonenal.
Protein Sci., 19, 2010
3QJF
  • Download 3qjf
  • View 3qjf
Molmil generated image of 3qjf
CRYSTAL STRUCTURE OF THE 2B4 TCR
Descriptor:2B4 alpha chain, 2B4 beta chain
Authors:Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C.
Deposit date:2011-01-28
Release date:2011-04-27
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
3HL6
  • Download 3hl6
  • View 3hl6
Molmil generated image of 3hl6
STAPHYLOCOCCUS AUREUS PATHOGENICITY ISLAND 3 ORF9 PROTEIN
Descriptor:Pathogenicity island protein, CHLORIDE ION
Authors:Kruse, A.C., Huseby, M., Shi, K., Digre, J., Schlievert, P.M., Ohlendorf, D.H., Earhart, C.A.
Deposit date:2009-05-26
Release date:2010-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional studies of a pathogenicity island protein from Staphylococcus aureus
To be Published
5HK1
  • Download 5hk1
  • View 5hk1
Molmil generated image of 5hk1
HUMAN SIGMA-1 RECEPTOR BOUND TO PD144418
Descriptor:Sigma non-opioid intracellular receptor 1, 3-(4-methylphenyl)-5-(1-propyl-3,6-dihydro-2H-pyridin-5-yl)-1,2-oxazole, SULFATE ION, ...
Authors:Schmidt, H.R., Zheng, S., Gurpinar, E., Koehl, A., Manglik, A., Kruse, A.C.
Deposit date:2016-01-13
Release date:2016-04-06
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (2.5051 Å)
Cite:Crystal structure of the human sigma 1 receptor.
Nature, 532, 2016
3I46
  • Download 3i46
  • View 3i46
Molmil generated image of 3i46
CRYSTAL STRUCTURE OF BETA TOXIN FROM STAPHYLOCOCCUS AUREUS F277A, P278A MUTANT WITH BOUND CALCIUM IONS
Descriptor:Beta-hemolysin, CALCIUM ION, CHLORIDE ION
Authors:Huseby, M., Shi, K., Kruse, A.C., Ohlendorf, D.H.
Deposit date:2009-07-01
Release date:2010-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and biological functions of beta toxin from Staphylococcus aureus: Role of the hydrophobic beta hairpin in virulence
To be Published
4JQI
  • Download 4jqi
  • View 4jqi
Molmil generated image of 4jqi
STRUCTURE OF ACTIVE BETA-ARRESTIN1 BOUND TO A G PROTEIN-COUPLED RECEPTOR PHOSPHOPEPTIDE
Descriptor:Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ...
Authors:Shukla, A.K., Manglik, A., Kruse, A.C., Xiao, K., Reis, R.I., Tseng, W.C., Staus, D.P., Hilger, D., Uysal, S., Huang, L.H., Paduch, M., Shukla, P.T., Koide, A., Koide, S., Weis, W.I., Kossiakoff, A.A., Kobilka, B.K., Lefkowitz, R.J.
Deposit date:2013-03-20
Release date:2013-04-17
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Nature, 497, 2013
5VNW
  • Download 5vnw
  • View 5vnw
Molmil generated image of 5vnw
CRYSTAL STRUCTURE OF NB.B201 BOUND TO HUMAN SERUM ALBUMIN
Descriptor:Serum albumin, Nb.b201, GLYCEROL, ...
Authors:McMahon, C., Kruse, A.C.
Deposit date:2017-05-01
Release date:2018-02-21
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Yeast surface display platform for rapid discovery of conformationally selective nanobodies.
Nat. Struct. Mol. Biol., 25, 2018
3QIB
  • Download 3qib
  • View 3qib
Molmil generated image of 3qib
CRYSTAL STRUCTURE OF THE 2B4 TCR IN COMPLEX WITH MCC/I-EK
Descriptor:H-2 class II histocompatibility antigen, E-K alpha chain, MHC class II E-beta-k, ...
Authors:Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C.
Deposit date:2011-01-26
Release date:2011-04-27
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
3QIU
  • Download 3qiu
  • View 3qiu
Molmil generated image of 3qiu
CRYSTAL STRUCTURE OF THE 226 TCR IN COMPLEX WITH MCC/I-EK
Descriptor:H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, E-K alpha chain, MHC CLASS II H2-IA-BETA CHAIN, ...
Authors:Kruse, A.C., Ely, L.K., Newell, E.W., Davis, M.M., Garcia, K.C.
Deposit date:2011-01-27
Release date:2011-04-27
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of specificity and cross-reactivity in T cell receptors specific for cytochrome c-I-E(k).
J.Immunol., 186, 2011
3TF7
  • Download 3tf7
  • View 3tf7
Molmil generated image of 3tf7
42F3 QL9/H2-LD COMPLEX
Descriptor:H2-Ld SBM2, QL9 peptide (QLSPFPFDL), 42F3 Mut7 scFv (42F3 alpha chain, ...
Authors:Adams, J.J., Kranz, D.M., Garcia, K.C.
Deposit date:2011-08-15
Release date:2011-12-07
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
3TFK
  • Download 3tfk
  • View 3tfk
Molmil generated image of 3tfk
42F3-P4B10/H2-LD
Descriptor:H2-Ld SBM2, p4B10 peptide, 42F3 alpha, ...
Authors:Adams, J.J., Kranz, D.M., Garcia, K.C.
Deposit date:2011-08-15
Release date:2011-12-07
Last modified:2012-01-18
Method:X-RAY DIFFRACTION (2.753 Å)
Cite:T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex.
Immunity, 35, 2011
4LDE
  • Download 4lde
  • View 4lde
Molmil generated image of 4lde
STRUCTURE OF BETA2 ADRENOCEPTOR BOUND TO BI167107 AND AN ENGINEERED NANOBODY
Descriptor:Lysozyme, Beta-2 adrenergic receptor, Camelid Antibody Fragment, ...
Authors:Ring, A.M., Manglik, A., Kruse, A.C., Enos, M.D., Weis, W.I., Garcia, K.C., Kobilka, B.K.
Deposit date:2013-06-24
Release date:2013-09-25
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody.
Nature, 502, 2013
3I5V
  • Download 3i5v
  • View 3i5v
Molmil generated image of 3i5v
CRYSTAL STRUCTURE OF BETA TOXIN 275-280 FROM STAPHYLOCOCCUS AUREUS
Descriptor:Beta-hemolysin, DIACYL GLYCEROL
Authors:Huseby, M., Shi, K., Kruse, A.C., Ohlendorf, D.H.
Deposit date:2009-07-06
Release date:2010-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and biological functions of beta toxin from Staphylococcus aureus: Role of the hydrophobic beta hairpin in virulence
To be Published
4DKL
  • Download 4dkl
  • View 4dkl
Molmil generated image of 4dkl
CRYSTAL STRUCTURE OF THE MU-OPIOID RECEPTOR BOUND TO A MORPHINAN ANTAGONIST
Descriptor:Mu-type opioid receptor, lysozyme chimera, methyl 4-{[(5beta,6alpha)-17-(cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-yl]amino}-4-oxobutanoate, ...
Authors:Manglik, A., Kruse, A.C., Kobilka, T.S., Thian, F.S., Mathiesen, J.M., Sunahara, R.K., Pardo, L., Weis, W.I., Kobilka, B.K., Granier, S.
Deposit date:2012-02-03
Release date:2012-03-21
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the {mu}-opioid receptor bound to a morphinan antagonist.
Nature, 485, 2012
6BE6
  • Download 6be6
  • View 6be6
Molmil generated image of 6be6
ADAM10 EXTRACELLULAR DOMAIN
Descriptor:Disintegrin and metalloproteinase domain-containing protein 10, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
Authors:Seegar, T.C.M.
Deposit date:2017-10-24
Release date:2017-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Regulated Proteolysis by the alpha-Secretase ADAM10.
Cell, 171, 2017
5IUS
  • Download 5ius
  • View 5ius
Molmil generated image of 5ius
CRYSTAL STRUCTURE OF HUMAN PD-L1 IN COMPLEX WITH HIGH AFFINITY PD-1 MUTANT
Descriptor:Programmed cell death protein 1, Programmed cell death 1 ligand 1, CHLORIDE ION
Authors:Pascolutti, R., Sun, X., Kao, J., Maute, R., Ring, A.M., Bowman, G.R., Kruse, A.C.
Deposit date:2016-03-18
Release date:2016-09-28
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.889 Å)
Cite:Structure and Dynamics of PD-L1 and an Ultra-High-Affinity PD-1 Receptor Mutant.
Structure, 24, 2016
6DK0
  • Download 6dk0
  • View 6dk0
Molmil generated image of 6dk0
HUMAN SIGMA-1 RECEPTOR BOUND TO NE-100
Descriptor:Sigma non-opioid intracellular receptor 1, N-{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl}-N-propylpropan-1-amine, SULFATE ION, ...
Authors:Schmidt, H.R., Kruse, A.C.
Deposit date:2018-05-28
Release date:2018-10-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for sigma1receptor ligand recognition.
Nat. Struct. Mol. Biol., 25, 2018
<123>