8FRN

Acinetobacter baylyi LptB2FG bound to lipopolysaccharide and Zosurabalpin

Summary for 8FRN

Entry DOI	10.2210/pdb8frn/pdb
EMDB information	29400 29401 29402 29403 29404
Descriptor	Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, LPS export ABC transporter permease LptG, ... (6 entities in total)
Functional Keywords	lipopolysaccharide, abc, atpase, antibiotic, macrocyclic peptide, gram-negative bacteria, eskape, lipid transport
Biological source	Acinetobacter baylyi ADP1 More
Total number of polymer chains	4
Total formula weight	143986.35
Authors	Pahil, K.S.,Gilman, M.S.A.,Kruse, A.C.,Kahne, D. (deposition date: 2023-01-07, release date: 2024-01-03, Last modification date: 2024-01-31)
Primary citation	Pahil, K.S.,Gilman, M.S.A.,Baidin, V.,Clairfeuille, T.,Mattei, P.,Bieniossek, C.,Dey, F.,Muri, D.,Baettig, R.,Lobritz, M.,Bradley, K.,Kruse, A.C.,Kahne, D. A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature, 625:572-577, 2024 Cited by PubMed: 38172635 DOI: 10.1038/s41586-023-06799-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation