7JIC

Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment

Summary for 7JIC

• Entry DOI: 10.2210/pdb7jic/pdb
• EMDB information: 22344
• Descriptor: B-lymphocyte antigen CD19, CD81 antigen, Coltuximab Heavy Chain, ... (4 entities in total)
• Functional Keywords: tetraspanin, fab, complex, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 110516.73

Authors

Susa, K.J.,Rawson, S.,Kruse, A.C.,Blacklow, S.C. (deposition date: 2020-07-23, release date: 2021-01-20)

• Primary citation: Susa, K.J.,Rawson, S.,Kruse, A.C.,Blacklow, S.C.; Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81; Science, 371:300-304, 2021; DOI: 10.1126/science.abd9836

Experimental method

ELECTRON MICROSCOPY (3.8 Å)