Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7TMW

Cryo-EM structure of the relaxin receptor RXFP1 in complex with heterotrimeric Gs

Summary for 7TMW
Entry DOI10.2210/pdb7tmw/pdb
EMDB information26003
DescriptorRelaxin receptor 1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short fusion, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (4 entities in total)
Functional Keywordsgpcr, complex, signaling, membrane protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight177282.42
Authors
Erlandson, S.C.,Rawson, S.,Kruse, A.C. (deposition date: 2022-01-20, release date: 2023-02-15, Last modification date: 2023-08-09)
Primary citationErlandson, S.C.,Rawson, S.,Osei-Owusu, J.,Brock, K.P.,Liu, X.,Paulo, J.A.,Mintseris, J.,Gygi, S.P.,Marks, D.S.,Cong, X.,Kruse, A.C.
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition.
Nat.Chem.Biol., 19:1013-1021, 2023
Cited by
PubMed: 37081311
DOI: 10.1038/s41589-023-01321-6
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.2 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon