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4C8R
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HUMAN GAMMA-BUTYROBETAINE DIOXYGENASE (BBOX1) IN COMPLEX WITH NI(II) AND N-(3-HYDROXYPICOLINOYL)-S-(PYRIDIN-2-YLMETHYL)-L-CYSTEINE (AR692B)
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, NICKEL (II) ION, ZINC ION, ...
Authors:Chowdhury, R., Rydzik, A.M., Kochan, G.T., McDonough, M.A., Schofield, C.J.
Deposit date:2013-10-01
Release date:2014-05-14
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Modulating carnitine levels by targeting its biosynthesis pathway - selective inhibition of gamma-butyrobetaine hydroxylase.
Chem Sci, 5, 2014
2VZE
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH AMP
Descriptor:ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL, ADENOSINE MONOPHOSPHATE, ...
Authors:Yue, W.W., Kochan, G.T., Pilka, E.S., Bhatia, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Wikstrom, M., Bountra, C., Oppermann, U.
Deposit date:2008-07-31
Release date:2008-10-14
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Snapshots for the Conformation- Dependent Catalysis by Human Medium-Chain Acyl- Coenzyme a Synthetase Acsm2A.
J.Mol.Biol., 388, 2009
2WD9
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH IBUPROFEN
Descriptor:ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL, IBUPROFEN, ...
Authors:Yue, W.W., Kochan, G.T., Pilka, E.S., Bhatia, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U.
Deposit date:2009-03-21
Release date:2009-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Snapshots for the Conformation- Dependent Catalysis by Human Medium-Chain Acyl- Coenzyme a Synthetase Acsm2A.
J.Mol.Biol., 388, 2009
3B7W
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A, WITH L64P MUTATION
Descriptor:Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor, MAGNESIUM ION, ...
Authors:Pilka, E.S., Kochan, G.T., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2007-10-31
Release date:2007-11-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.
J.Mol.Biol., 388, 2009
3C5E
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH ATP
Descriptor:Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor, MAGNESIUM ION, ...
Authors:Pilka, E.S., Kochan, G.T., Bhatia, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2008-01-31
Release date:2008-02-26
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.
J.Mol.Biol., 388, 2009
3DAY
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH AMP-CPP
Descriptor:Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor, MAGNESIUM ION, ...
Authors:Pilka, E.S., Kochan, G.T., Yue, W.W., Bhatia, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Wikstrom, M., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2008-05-30
Release date:2008-07-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.
J.Mol.Biol., 388, 2009
3GPC
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN A COMPLEX WITH COA
Descriptor:Acyl-coenzyme A synthetase ACSM2A, MAGNESIUM ION, COENZYME A
Authors:Pilka, E.S., Kochan, G.T., Yue, W.W., Bhatia, C., Von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
Deposit date:2009-03-23
Release date:2009-04-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A
J.Mol.Biol., 388, 2009
4CWD
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CRYSTAL STRUCTURE OF HUMAN GAMMA-BUTYROBETAINE,2-OXOGLUTARATE IN COMPLEX WITH 449, A NOVEL SUBSTRATE
Descriptor:GAMMA-BUTYROBETAINE DIOXYGENASE, NICKEL (II) ION, ZINC ION, ...
Authors:McDonough, M.A., Kochan, G., Rydzik, A., Schofield, C.J.
Deposit date:2014-04-02
Release date:2014-09-17
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:Oxygenase-catalyzed desymmetrization of N,N-dialkyl-piperidine-4-carboxylic acids.
Angew. Chem. Int. Ed. Engl., 53, 2014