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4X34
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BU of 4x34 by Molmil
Crystal structure of the 53BP1 tandem tudor domain in complex with p53K381acK382me2
Descriptor: THR-SER-ARG-HIS-ALY-MLY-LEU-MET-PHE-LYS, Tumor suppressor p53-binding protein 1
Authors:Tong, Q, Kutateladze, T.G.
Deposit date:2014-11-27
Release date:2015-03-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:An Acetyl-Methyl Switch Drives a Conformational Change in p53.
Structure, 23, 2015
2L5A
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BU of 2l5a by Molmil
Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3
Descriptor: Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4
Authors:Zhou, Z, Feng, H, Zhou, B, Ghirlando, R, Hu, K, Zwolak, A, Jenkins, L, Xiao, H, Tjandra, N, Wu, C, Bai, Y.
Deposit date:2010-10-28
Release date:2011-03-16
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3.
Nature, 472, 2011
8T3V
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BU of 8t3v by Molmil
Cryo-EM structure of the DHA bound FFA1-Gq complex
Descriptor: CHOLESTEROL, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 1, ...
Authors:Zhang, X, Tikhonova, I, Milligan, G, Zhang, C.
Deposit date:2023-06-07
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
8T3O
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BU of 8t3o by Molmil
Cryo-EM structure of the TUG-891 bound FFA4-Gq complex
Descriptor: (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, ...
Authors:Zhang, X, Tikhonova, I, Milligan, G, Zhang, C.
Deposit date:2023-06-07
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
8T3Q
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BU of 8t3q by Molmil
Cryo-EM structure of the DHA bound FFA4-Gq complex
Descriptor: DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Zhang, X, Tikhonova, I, Milligan, G, Zhang, C.
Deposit date:2023-06-07
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
8T3S
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BU of 8t3s by Molmil
Cryo-EM structure of the Butyrate bound FFA2-Gq complex
Descriptor: CHOLESTEROL, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Zhang, X, Tikhonova, I, Milligan, G, Zhang, C.
Deposit date:2023-06-07
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Structural basis for the ligand recognition and signaling of free fatty acid receptors.
Sci Adv, 10, 2024
8G05
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BU of 8g05 by Molmil
Cryo-EM structure of an orphan GPCR-Gi protein signaling complex
Descriptor: 6-(octylamino)pyrimidine-2,4(3H,5H)-dione, CHOLESTEROL, G-protein coupled receptor 84, ...
Authors:Zhang, X, Wang, Y.J, Li, X, Liu, G.B, Gong, W.M, Zhang, C.
Deposit date:2023-01-31
Release date:2023-11-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Pro-phagocytic function and structural basis of GPR84 signaling.
Nat Commun, 14, 2023
6SS4
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BU of 6ss4 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021181
Descriptor: Arginase-2, mitochondrial, Fab C0021181 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS2
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BU of 6ss2 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021158
Descriptor: Arginase-2, mitochondrial, Fab C0021158 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS0
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BU of 6ss0 by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021181
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fab C0021181 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS6
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BU of 6ss6 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0020187
Descriptor: Arginase-2, mitochondrial, Fab C0020187 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6TUL
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BU of 6tul by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021177
Descriptor: D-MALATE, Fab C0021177 heavy chain (IgG1), Fab C0021177 light chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2020-01-07
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS5
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BU of 6ss5 by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0020187
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SRX
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BU of 6srx by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021158
Descriptor: ACETATE ION, CHLORIDE ION, Fab C0021158 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SRV
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BU of 6srv by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021144
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2020-09-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12

225158

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