Author results

3UN4
  • Download 3un4
  • View 3un4
Molmil generated image of 3un4
YEAST 20S PROTEASOME IN COMPLEX WITH PR-957 (MORPHOLINE)
Descriptor:Proteasome component Y7, Proteasome component Y13, Proteasome component PRE6, ...
Authors:Huber, E., Basler, M., Schwab, R., Heinemeyer, W., Kirk, C., Groettrup, M., Groll, M.
Deposit date:2011-11-15
Release date:2012-02-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
Cell(Cambridge,Mass.), 148, 2012
3UN8
  • Download 3un8
  • View 3un8
Molmil generated image of 3un8
YEAST 20S PROTEASOME IN COMPLEX WITH PR-957 (EPOXIDE)
Descriptor:Proteasome component Y7, Proteasome component Y13, Proteasome component PRE6, ...
Authors:Huber, E., Basler, M., Schwab, R., Heinemeyer, W., Kirk, C., Groettrup, M., Groll, M.
Deposit date:2011-11-15
Release date:2012-02-29
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
Cell(Cambridge,Mass.), 148, 2012
3UNB
  • Download 3unb
  • View 3unb
Molmil generated image of 3unb
MOUSE CONSTITUTIVE 20S PROTEASOME IN COMPLEX WITH PR-957
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Huber, E., Basler, M., Schwab, R., Heinemeyer, W., Kirk, C., Groettrup, M., Groll, M.
Deposit date:2011-11-15
Release date:2012-02-29
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
Cell(Cambridge,Mass.), 148, 2012
3UNE
  • Download 3une
  • View 3une
Molmil generated image of 3une
MOUSE CONSTITUTIVE 20S PROTEASOME
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Huber, E., Basler, M., Schwab, R., Heinemeyer, W., Kirk, C., Groettrup, M., Groll, M.
Deposit date:2011-11-15
Release date:2012-02-29
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
Cell(Cambridge,Mass.), 148, 2012
3UNF
  • Download 3unf
  • View 3unf
Molmil generated image of 3unf
MOUSE 20S IMMUNOPROTEASOME IN COMPLEX WITH PR-957
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Huber, E., Basler, M., Schwab, R., Heinemeyer, W., Kirk, C., Groettrup, M., Groll, M.
Deposit date:2011-11-15
Release date:2012-02-29
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
Cell(Cambridge,Mass.), 148, 2012
3UNH
  • Download 3unh
  • View 3unh
Molmil generated image of 3unh
MOUSE 20S IMMUNOPROTEASOME
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, Proteasome subunit alpha type-7, ...
Authors:Huber, E., Basler, M., Schwab, R., Heinemeyer, W., Kirk, C., Groettrup, M., Groll, M.
Deposit date:2011-11-15
Release date:2012-02-29
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity.
Cell(Cambridge,Mass.), 148, 2012
4Q1S
  • Download 4q1s
  • View 4q1s
Molmil generated image of 4q1s
YEAST 20S PROTEASOME IN COMPLEX WITH KENDOMYCIN
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Beck, P., Heinemeyer, W., Spaeth, A., Elnakady, Y., Mueller, R., Groll, M.
Deposit date:2014-04-04
Release date:2014-07-30
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interactions of the natural product kendomycin and the 20S proteasome.
J.Mol.Biol., 426, 2014
4QUX
  • Download 4qux
  • View 4qux
Molmil generated image of 4qux
YCP BETA5-A49T-MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QUY
  • Download 4quy
  • View 4quy
Molmil generated image of 4quy
YCP BETA5-A49S-MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV0
  • Download 4qv0
  • View 4qv0
Molmil generated image of 4qv0
YCP BETA5-A49T-A50V-DOUBLE MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV1
  • Download 4qv1
  • View 4qv1
Molmil generated image of 4qv1
YCP BETA5-M45A MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV3
  • Download 4qv3
  • View 4qv3
Molmil generated image of 4qv3
YCP BETA5-M45V MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV4
  • Download 4qv4
  • View 4qv4
Molmil generated image of 4qv4
YCP BETA5-M45T MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV5
  • Download 4qv5
  • View 4qv5
Molmil generated image of 4qv5
YCP BETA5-M45I MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV6
  • Download 4qv6
  • View 4qv6
Molmil generated image of 4qv6
YCP BETA5-A49V MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV7
  • Download 4qv7
  • View 4qv7
Molmil generated image of 4qv7
YCP BETA5-A50V MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV8
  • Download 4qv8
  • View 4qv8
Molmil generated image of 4qv8
YCP BETA5-C52F MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QV9
  • Download 4qv9
  • View 4qv9
Molmil generated image of 4qv9
YCP BETA5-C63F MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-14
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QVL
  • Download 4qvl
  • View 4qvl
Molmil generated image of 4qvl
YCP IN COMPLEX WITH BORTEZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-15
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QVM
  • Download 4qvm
  • View 4qvm
Molmil generated image of 4qvm
YCP BETA5-M45A MUTANT IN COMPLEX WITH BORTEZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-15
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QVN
  • Download 4qvn
  • View 4qvn
Molmil generated image of 4qvn
YCP BETA5-M45V MUTANT IN COMPLEX WITH BORTEZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-15
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QVP
  • Download 4qvp
  • View 4qvp
Molmil generated image of 4qvp
YCP BETA5-M45T MUTANT IN COMPLEX WITH BORTEZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-15
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QVQ
  • Download 4qvq
  • View 4qvq
Molmil generated image of 4qvq
YCP BETA5-M45I MUTANT IN COMPLEX WITH BORTEZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-15
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QVV
  • Download 4qvv
  • View 4qvv
Molmil generated image of 4qvv
YCP BETA5-A49V MUTANT IN COMPLEX WITH BORTEZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-16
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015
4QVW
  • Download 4qvw
  • View 4qvw
Molmil generated image of 4qvw
YCP BETA5-A49S-MUTANT IN COMPLEX WITH BORTEZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Heinemeyer, W., Groll, M.
Deposit date:2014-07-16
Release date:2015-02-04
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914.
Structure, 23, 2015