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4CFH
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STRUCTURE OF AN ACTIVE FORM OF MAMMALIAN AMPK
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2013-11-18
公開日2013-12-25
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
1W9R
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SOLUTION STRUCTURE OF CHOLINE BINDING PROTEIN A, DOMAIN R2, THE MAJOR ADHESIN OF STREPTOCOCCUS PNEUMONIAE
分子名称:CHOLINE BINDING PROTEIN A
著者Luo, R., Mann, B., Lewis, W.S., Rowe, A., Heath, R., Stewart, M.L., Hamburger, A.E., Bjorkman, P.J., Sivakolundu, S., Lacy, E.R., Tuomanen, E., Kriwacki, R.W.
登録日2004-10-15
公開日2005-02-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of Choline Binding Protein A, the Major Adhesin of Streptococcus Pneumoniae
Embo J., 24, 2005
2Y8L
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH TWO ADP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2011-02-07
公開日2011-03-16
最終更新日2014-01-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2Y8Q
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH ONE ADP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2011-02-09
公開日2011-03-16
最終更新日2012-11-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
2YA3
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STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEX WITH COUMARIN ADP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Sanders, M.J., Underwood, E., Heath, R., Mayer, F., Carmena, D., Jing, C., Walker, P.A., Eccleston, J.F., Haire, L.F., Saiu, P., Howell, S.A., Aasland, R., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2011-02-17
公開日2011-03-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of Mammalian Ampk and its Regulation by Adp
Nature, 472, 2011
3T4N
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STRUCTURE OF THE REGULATORY FRAGMENT OF SACCHAROMYCES CEREVISIAE AMPK IN COMPLEX WITH ADP
分子名称:Carbon catabolite-derepressing protein kinase, SNF1 protein kinase subunit beta-2, Nuclear protein SNF4, ...
著者Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker, P.A., Haire, L.F., Ogrodowicz, R., Martin, S.R., Schmdit, M.C., Gamblin, S.J., Carling, D.
登録日2011-07-26
公開日2011-11-09
最終更新日2011-11-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
3TDH
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STRUCTURE OF THE REGULATORY FRAGMENT OF SCCHAROMYCES CEREVISIAE AMPK IN COMPLEX WITH AMP
分子名称:Carbon catabolite-derepressing protein kinase, SNF1 protein kinase subunit beta-2, Nuclear protein SNF4, ...
著者Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker, P.A., Haire, L.F., Ogrodowicz, R., Martin, S.R., Schmidt, M.C., Gamblin, S.J., Carling, D.
登録日2011-08-11
公開日2011-11-09
最終更新日2011-11-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
3TE5
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STRUCTURE OF THE REGULATORY FRAGMENT OF SACCHROMYCES CEREVISIAE AMPK IN COMPLEX WITH NADH
分子名称:Carbon catabolite-derepressing protein kinase, SNF1 protein kinase subunit beta-2, Nuclear protein SNF4, ...
著者Mayer, F.V., Heath, R., Underwood, E., Sanders, M.J., Carmena, D., McCartney, R., Leiper, F.C., Xiao, B., Jing, C., Walker, P.A., Haire, L.F., Ogrodowicz, R., Martin, S.R., Schmidt, M.C., Gamblin, S.J., Carling, D.
登録日2011-08-12
公開日2011-11-09
最終更新日2011-11-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase.
Cell Metab, 14, 2011
2V8Q
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-13
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V92
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH ATP-AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-20
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
2V9J
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CRYSTAL STRUCTURE OF THE REGULATORY FRAGMENT OF MAMMALIAN AMPK IN COMPLEXES WITH MG.ATP-AMP
分子名称:5'-AMP-ACTIVATED PROTEIN KINASE CATALYTIC SUBUNIT ALPHA-1, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-2, 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1, ...
著者Xiao, B., Heath, R., Saiu, P., Leiper, F.C., Leone, P., Jing, C., Walker, P.A., Haire, L., Eccleston, J.F., Davis, C.T., Martin, S.R., Carling, D., Gamblin, S.J.
登録日2007-08-23
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural Basis for AMP Binding to Mammalian AMP-Activated Protein Kinase
Nature, 449, 2007
3VKX
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STRUCTURE OF PCNA
分子名称:Proliferating cell nuclear antigen, 3,5,3'TRIIODOTHYRONINE, SULFATE ION, ...
著者Hashimoto, H., Hishiki, A., Shimizu, T., Sato, M., Punchihewa, C., Connelly, M., Actis, M., Waddell, B., Pagala, V., Fujii, N.
登録日2011-11-26
公開日2012-03-14
最終更新日2013-08-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of small molecule proliferating cell nuclear antigen (PCNA) inhibitor that disrupts interactions with PIP-box proteins and inhibits DNA replication
J.Biol.Chem., 287, 2012
3WGW
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STRUCTURE OF PCNA BOUND TO A SMALL MOLECULE INHIBITOR
分子名称:Proliferating cell nuclear antigen, 4-{4-[(2S)-2-amino-3-hydroxypropyl]-2,6-diiodophenoxy}phenol, SULFATE ION
著者Hashimoto, H.
登録日2013-08-12
公開日2014-02-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A small molecule inhibitor of monoubiquitinated proliferating cell nuclear antigen (PCNA) inhibits repair of interstrand DNA crosslink, enhances DNA double-strand break, and sensitizes cancer cells to cisplatin
J.Biol.Chem., 2014