6TD4

IRF4 DNA-binding domain surface entropy mutant apo structure

Summary for 6TD4

• Entry DOI: 10.2210/pdb6td4/pdb
• Descriptor: Interferon regulatory factor 4, CHLORIDE ION (3 entities in total)
• Functional Keywords: dna binding domain, surface entropy mutant, apo, dna binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 13974.23

Authors

Tucker, J.A.,Martin, M.P.,Wang, L.Z.,Jennings, C.,Heath, R. (deposition date: 2019-11-07, release date: 2020-11-18, Last modification date: 2021-06-23)

• Primary citation: Tatum, N.J.,Scott, R.,Doody, G.M.,Hickson, I.,Jennings, C.,Martin, M.P.,Tooze, R.M.,Tucker, J.A.,Wittner, A.,Wang, L.Z.,Wright, E.K.,Wedge, S.R.,Noble, M.E.M.; Cancer-associated mutations in the IRF4 DNA-binding domain confer no disadvantage in DNA-binding affinity and may increase transcriptional activity; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.71 Å)