6TD4
IRF4 DNA-binding domain surface entropy mutant apo structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interferon regulatory factor 4 | polymer | 121 | 13938.8 | 1 | UniProt (Q15306) Pfam (PF00605) | Homo sapiens (Human) | IRF-4,Lymphocyte-specific interferon regulatory factor,LSIRF,Multiple myeloma oncogene 1,NF-EM5 |
| 2 | B (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | C (A) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A: 20 - 132 (UniProt: Q15306)
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | expression tag |
| Pro 15 | - | expression tag |
| Met 16 | - | expression tag |
| Gly 17 | - | expression tag |
| His 18 | - | expression tag |
| Met 19 | - | expression tag |
| Ala 45 | Glu 45 | engineered mutation |
| Ala 46 | Glu 46 | engineered mutation |
| Ala 47 | Lys 47 | engineered mutation |
| Ser 99 | Cys 99 | engineered mutation |
| Leu 133 | - | expression tag |
| Glu 134 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13938.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 13974.2 |
