4BH6
 
 | | Insights into degron recognition by APC coactivators from the structure of an Acm1-Cdh1 complex | | Descriptor: | APC/C ACTIVATOR PROTEIN CDH1, APC/C-CDH1 MODULATOR 1 | | Authors: | He, J, Chao, W.C.H, Zhang, Z, Yang, J, Cronin, N, Barford, D. | | Deposit date: | 2013-03-29 | | Release date: | 2013-06-05 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Insights Into Degron Recognition by Apc/C Coactivators from the Structure of an Acm1-Cdh1 Complex.
Mol.Cell, 50, 2013
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3P57
 | | Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA | | Descriptor: | DNA (5'-D(*A*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3'), Histone acetyltransferase p300, ... | | Authors: | He, J, Ye, J, Riquelme, C, Liu, J.O. | | Deposit date: | 2010-10-08 | | Release date: | 2011-08-10 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.1921 Å) | | Cite: | Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly.
Nucleic Acids Res., 39, 2011
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4ADY
 | | Crystal structure of 26S proteasome subunit Rpn2 | | Descriptor: | 26S PROTEASOME REGULATORY SUBUNIT RPN2 | | Authors: | Kulkarni, K, He, J, Da Fonseca, P.C.A, Krutauz, D, Glickman, M.H, Barford, D, Morris, E.P. | | Deposit date: | 2012-01-04 | | Release date: | 2012-03-14 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The Structure of the 26S Proteasome Subunit Rpn2 Reveals its Pc Repeat Domain as a Closed Toroid of Two Concentric Alpha-Helical Rings
Structure, 20, 2012
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3RCP
 | | Crystal structure of the FAPP1 pleckstrin homology domain | | Descriptor: | GLYCEROL, Pleckstrin homology domain-containing family A member 3 | | Authors: | Roy, S, He, J, Kutateladze, T.G. | | Deposit date: | 2011-03-31 | | Release date: | 2011-04-20 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Molecular Basis of Phosphatidylinositol 4-Phosphate and ARF1 GTPase Recognition by the FAPP1 Pleckstrin Homology (PH) Domain.
J.Biol.Chem., 286, 2011
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4L94
 | | Crystal structure of Human Hsp90 with S46 | | Descriptor: | (4-hydroxyphenyl)(4-methylpiperazin-1-yl)methanone, Heat shock protein HSP 90-alpha | | Authors: | Li, J, Ren, J, Yang, M, Xiong, B, He, J. | | Deposit date: | 2013-06-18 | | Release date: | 2014-06-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.649 Å) | | Cite: | Identification of a new series of potent diphenol HSP90 inhibitors by fragment merging and structure-based optimization
Bioorg.Med.Chem.Lett., 24, 2014
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9KML
 | | apo mTAUT in inward open I state | | Descriptor: | CHLORIDE ION, Light chain of 9D5 fab, Sodium- and chloride-dependent taurine transporter, ... | | Authors: | She, J, Wang, M, He, J. | | Deposit date: | 2024-11-16 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Molecular basis for substrate recognition and transport of mammalian taurine transporters
To Be Published
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9KYO
 | | GES bound mTAUT | | Descriptor: | CHLORIDE ION, Heavy chain of 9D5 fab, Light chain of 9D5 fab, ... | | Authors: | She, J, Wang, M.X, He, J. | | Deposit date: | 2024-12-09 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Molecular basis for substrate recognition and transport of mammalian taurine transporters
To Be Published
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9KMJ
 | | Taurine bound hTAUT | | Descriptor: | 2-AMINOETHANESULFONIC ACID, CHLORIDE ION, Heavy chain of 9D5 Fab, ... | | Authors: | She, J, Wang, M, He, J. | | Deposit date: | 2024-11-16 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Molecular basis for substrate recognition and transport of mammalian taurine transporters
To Be Published
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9KMK
 | | apo mTAUT in inward open II state | | Descriptor: | CHLORIDE ION, Sodium- and chloride-dependent taurine transporter, heavy chain of 9D5 fab, ... | | Authors: | She, J, Wang, M, He, J. | | Deposit date: | 2024-11-16 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Molecular basis for substrate recognition and transport of mammalian taurine transporters
To Be Published
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9KMM
 | | IAA bound mTAUT | | Descriptor: | 2H-IMIDAZOL-4-YLACETIC ACID, CHLORIDE ION, SODIUM ION, ... | | Authors: | She, J, Wang, M, He, J. | | Deposit date: | 2024-11-16 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Molecular basis for substrate recognition and transport of mammalian taurine transporters
To Be Published
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9KMI
 | | Taurine bound mTAUT | | Descriptor: | 2-AMINOETHANESULFONIC ACID, CHLORIDE ION, Heavy chain of 9D5 Fab, ... | | Authors: | She, J, Wang, M, He, J. | | Deposit date: | 2024-11-16 | | Release date: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Molecular basis for substrate recognition and transport of mammalian taurine transporters
To Be Published
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1KZZ
 | | DOWNSTREAM REGULATOR TANK BINDS TO THE CD40 RECOGNITION SITE ON TRAF3 | | Descriptor: | TNF receptor associated factor 3, TRAF family member-associated NF-kappa-b activator | | Authors: | Li, C, Ni, C.-Z, Havert, M.L, Cabezas, E, He, J, Kaiser, D, Reed, J.C, Satterthwait, A.C, Cheng, G, Ely, K.R. | | Deposit date: | 2002-02-08 | | Release date: | 2002-04-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Downstream regulator TANK binds to the CD40 recognition site on TRAF3.
Structure, 10, 2002
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3S8M
 | | The Crystal Structure of FabV | | Descriptor: | Enoyl-ACP Reductase | | Authors: | Li, H, Zhang, X.L, Bi, L.J, He, J, Jiang, T. | | Deposit date: | 2011-05-29 | | Release date: | 2011-11-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Determination of the Crystal Structure and Active Residues of FabV, the Enoyl-ACP Reductase from Xanthomonas oryzae.
Plos One, 6, 2011
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8HVT
 | | Structure of the human CLC-7/Ostm1 complex reveals a novel state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H(+)/Cl(-) exchange transporter 7, Osteopetrosis-associated transmembrane protein 1, ... | | Authors: | Zhang, Z.X, Chen, L, He, J, She, J. | | Deposit date: | 2022-12-27 | | Release date: | 2024-01-03 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure of the human CLC-7/Ostm1 complex reveals a novel state
JUSTC, 53, 2023
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7XTZ
 | | Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-1 Conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | Deposit date: | 2022-05-18 | | Release date: | 2022-07-20 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
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7XU1
 | | Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-122 Conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | Deposit date: | 2022-05-18 | | Release date: | 2022-07-20 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
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7XU4
 | | Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | Deposit date: | 2022-05-18 | | Release date: | 2022-07-20 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
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7XU5
 | | Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | Deposit date: | 2022-05-18 | | Release date: | 2022-07-20 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
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7XU3
 | | Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Closed Conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | Deposit date: | 2022-05-18 | | Release date: | 2022-07-20 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
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7XU6
 | | Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), incubated in Low pH after 40-Day Storage in PBS, Locked-2 Conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | | Deposit date: | 2022-05-18 | | Release date: | 2022-07-20 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Plos Pathog., 18, 2022
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3EOP
 | | Crystal Structure of the DUF55 domain of human thymocyte nuclear protein 1 | | Descriptor: | SULFATE ION, Thymocyte nuclear protein 1 | | Authors: | Yu, F, Song, A, Xu, C, Sun, L, Li, L, Tang, L, Hu, H, He, J. | | Deposit date: | 2008-09-29 | | Release date: | 2009-09-29 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Determining the DUF55-domain structure of human thymocyte nuclear protein 1 from crystals partially twinned by tetartohedry
Acta Crystallogr.,Sect.D, 65, 2009
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7YE9
 | | SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... | | Authors: | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | Deposit date: | 2022-07-05 | | Release date: | 2022-08-24 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (4.17 Å) | | Cite: | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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7YDY
 | | SARS-CoV-2 Spike (6P) in complex with 1 R1-32 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... | | Authors: | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | Deposit date: | 2022-07-04 | | Release date: | 2022-08-24 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (4.75 Å) | | Cite: | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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7YEG
 | | SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | Authors: | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | Deposit date: | 2022-07-05 | | Release date: | 2022-08-24 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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7YDI
 | | SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32, Light chain of R1-32, ... | | Authors: | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | | Deposit date: | 2022-07-04 | | Release date: | 2022-08-24 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
Nat Microbiol, 7, 2022
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