Author results

1B3U
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CRYSTAL STRUCTURE OF CONSTANT REGULATORY DOMAIN OF HUMAN PP2A, PR65ALPHA
分子名称:PROTEIN (PROTEIN PHOSPHATASE PP2A)
著者Groves, M.R., Hanlon, N., Turowski, P., Hemmings, B., Barford, D.
登録日1998-12-14
公開日1999-04-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs.
Cell(Cambridge,Mass.), 96, 1999
1BZC
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HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH TPI
分子名称:PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE), 4-CARBAMOYL-4-{[6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBONYL]-AMINO}-BUTYRIC ACID
著者Groves, M.R., Yao, Z.J., Jr Burke, T.R., Barford, D.
登録日1998-10-27
公開日1999-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.
Biochemistry, 37, 1998
1BZH
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CYCLIC PEPTIDE INHIBITOR OF HUMAN PTP1B
分子名称:PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B), PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B INHIBITOR)
著者Groves, M.R., Yao, Z.J., Burke Jr., T.R., Barford, D.
登録日1998-10-28
公開日1999-02-16
最終更新日2018-12-26
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.
Biochemistry, 37, 1998
1BZJ
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HUMAN PTP1B COMPLEXED WITH TPICOOH
分子名称:PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE), 6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBOXYLIC ACID
著者Groves, M.R., Yao, Z.-J., Barford Jr., D.T.B.
登録日1998-10-29
公開日1999-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.
Biochemistry, 37, 1998
1CZI
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CHYMOSIN COMPLEX WITH THE INHIBITOR CP-113972
分子名称:CHYMOSIN, CP-113972 (NORSTATINE-S-METHYL CYSTEINE-IODO-PHENYLALANINE-PROLINE)
著者Groves, M.R., Dhanaraj, V., Pitts, J.E., Badasso, M., Hoover, D., Nugent, P., Blundell, T.L.
登録日1997-01-15
公開日1997-04-01
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure.
Protein Eng., 11, 1998
1PCI
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PROCARICAIN
分子名称:PROCARICAIN
著者Groves, M.R., Taylor, M.A.J., Scott, M., Cummings, N.J., Pickersgill, R.W., Jenkins, J.A.
登録日1996-06-28
公開日1997-04-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The prosequence of procaricain forms an alpha-helical domain that prevents access to the substrate-binding cleft.
Structure, 4, 1996
2OB1
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PPM1 WITH 1,8-ANS
分子名称:Leucine carboxyl methyltransferase 1, PHOSPHATE ION
著者Groves, M.R.
登録日2006-12-18
公開日2007-01-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A method for the general identification of protein crystals in crystallization experiments using a noncovalent fluorescent dye.
Acta Crystallogr.,Sect.D, 63, 2007
2OB2
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PPM1 IN THE ABSENCE OF 1,8-ANS (CF 1JD)
分子名称:Leucine carboxyl methyltransferase 1, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Groves, M.R., Mueller, I.B., Kreplin, X., Mueller-Dieckmann, J.
登録日2006-12-18
公開日2007-01-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A method for the general identification of protein crystals in crystallization experiments using a noncovalent fluorescent dye.
Acta Crystallogr.,Sect.D, 63, 2007
3K7Y
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ASPARTATE AMINOTRANSFERASE OF PLASMODIUM FALCIPARUM
分子名称:Aspartate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ACETATE ION
著者Groves, M.R., Jordanova, R., Jain, R., Wrenger, C., Muller, I.B.
登録日2009-10-13
公開日2010-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Specific Inhibition of the Aspartate Aminotransferase of Plasmodium falciparum.
J.Mol.Biol., 405, 2011
5NKZ
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CRYSTAL STRUCTURE OF H. POLYMORPHA UBIQUITIN CONJUGATING ENZYME PEX4P IN COMPLEX WITH SOLUBLE DOMAIN OF PEX22P
分子名称:Ubiquitin-conjugating enzyme E2-21 kDa, Peroxin 22
著者Danda, N., Lunev, S., Ali, A., Groves, M.R., Williams, C.
登録日2017-04-03
公開日2018-01-24
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.
Biochem. Biophys. Res. Commun., 496, 2018
1MHN
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HIGH RESOLUTION CRYSTAL STRUCTURE OF THE SMN TUDOR DOMAIN
分子名称:Survival motor neuron protein
著者Sprangers, R., Groves, M.R., Sinning, I., Sattler, M.
登録日2002-08-20
公開日2003-03-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High Resolution X-ray and NMR Structures of the SMN Tudor Domain: conformational variation in the binding site for symmetrically dimethylated arginine residues
J.Mol.Biol., 327, 2003
1SMB
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CRYSTAL STRUCTURE OF GOLGI-ASSOCIATED PR-1 PROTEIN
分子名称:17kD fetal brain protein
著者Serrano, R.L., Kuhn, A., Hendricks, A., Helms, J.B., Sinning, I., Groves, M.R.
登録日2004-03-08
公開日2004-09-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism
J.Mol.Biol., 339, 2004
3FPV
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CRYSTAL STRUCTURE OF HBPS
分子名称:Extracellular haem-binding protein, FE (III) ION
著者Ortiz de Orue Lucana, D., Bogel, G., Zou, P., Groves, M.R.
登録日2009-01-06
公開日2009-01-20
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The oligomeric assembly of the novel haem-degrading protein HbpS is essential for interaction with its cognate two-component sensor kinase
J.Mol.Biol., 386, 2009
3FPW
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CRYSTAL STRUCTURE OF HBPS WITH BOUND IRON
分子名称:Extracellular haem-binding protein, FE (III) ION, PHOSPHATE ION
著者Ortiz de Orue Lucana, D., Bogel, G., Zou, P., Groves, M.R.
登録日2009-01-06
公開日2009-01-20
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The oligomeric assembly of the novel haem-degrading protein HbpS is essential for interaction with its cognate two-component sensor kinase
J.Mol.Biol., 386, 2009
5NFR
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CRYSTAL STRUCTURE OF MALATE DEHYDROGENASE FROM PLASMODIUM FALCIPARUM (PFMDH)
分子名称:Malate dehydrogenase, CITRIC ACID
著者Lunev, S., Romero, A.R., Batista, F.A., Wrenger, C., Groves, M.R.
登録日2017-03-15
公開日2018-01-31
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro.
PLoS ONE, 13, 2018
6HL7
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CRYSTAL STRUCTURE OF TRUNCATED ASPARTATE TRANSCARBAMOYLASE FROM PLASMODIUM FALCIPARUM WITH MUTATED ACTIVE SITE (R109A/K138A) AND N-CARBAMOYL-L-PHOSPHATE BOUND
分子名称:Aspartate transcarbamoylase, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER
著者Bosch, S.S., Lunev, S., Wrenger, C., Groves, M.R.
登録日2018-09-10
公開日2018-09-26
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Drug target validation of aspartate transcarbamoylase from Plasmodium falciparum
To Be Published
2W9Y
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THE STRUCTURE OF THE LIPID BINDING PROTEIN CE-FAR-7 FROM CAENORHABDITIS ELEGANS
分子名称:FATTY ACID/RETINOL BINDING PROTEIN PROTEIN 7, ISOFORM A, CONFIRMED BY TRANSCRIPT EVIDENCE, ...
著者Jordanova, R., Groves, M.R., Tucker, P.A.
登録日2009-01-30
公開日2009-10-20
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Fatty Acid and Retinoid Binding Proteins Have Distinct Binding Pockets for the Two Types of Cargo
J.Biol.Chem., 284, 2009
3L1P
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POU PROTEIN:DNA COMPLEX
分子名称:POU domain, class 5, transcription factor 1, ...
著者Vahokoski, J., Groves, M.R., Pogenberg, V., Wilmanns, M.
登録日2009-12-14
公開日2010-12-15
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A unique Oct4 interface is crucial for reprogramming to pluripotency
Nat.Cell Biol., 15, 2013
4BMW
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CRYSTAL STRUCTURE OF THE STREPTOMYCES RETICULI HBPS E78D, E81D DOUBLE MUTANT
分子名称:EXTRACELLULAR HAEM-BINDING PROTEIN
著者Wagener, S., Kursula, I., Wedderhoff, I., Groves, M.R., Ortiz de Orue Lucana, D.
登録日2013-05-11
公開日2013-09-25
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Iron Binding at Specific Sites within the Octameric Hbps Protects Streptomycetes from Iron-Mediated Oxidative Stress.
Plos One, 8, 2013
5FTP
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SULFUR SAD PHASING OF CDC23NTERM: DATA COLLECTION WITH A TAILORED X- RAY BEAM SIZE AT 2.69 A WAVELENGTH (4.6 KEV)
分子名称:ANAPHASE-PROMOTING COMPLEX SUBUNIT 8
著者Cianci, M., Groves, M.R., Barford, D., Schneider, T.R.
登録日2016-01-14
公開日2016-03-16
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Data Collection with a Tailored X-Ray Beam Size at 2.69 A Wavelength (4.6 Kev): Sulfur Sad Phasing of Cdc23Nterm
Acta Crystallogr.,Sect.D, 72, 2016
5ILN
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CRYSTAL STRUCTURE OF ASPARTATE TRANSCARBAMOYLASE FROM PLASMODIUM FALCIPARUM (PFATC) WITH BOUND CITRATE
分子名称:Aspartate carbamoyltransferase, GLYCEROL, PHOSPHATE ION, ...
著者Lunev, S., Bosch, S.S., Batista, F.D.A., Wrenger, C., Groves, M.R.
登録日2016-03-04
公開日2017-03-29
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Crystal structure of truncated Aspartate Transcarbamoylase from Plasmodium falciparum
To be published
5ILQ
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CRYSTAL STRUCTURE OF TRUNCATED UNLIGANDED ASPARTATE TRANSCARBAMOYLASE FROM PLASMODIUM FALCIPARUM
分子名称:Aspartate carbamoyltransferase, GLYCEROL, SULFATE ION
著者Lunev, S., Bosch, S.S., Batista, F.D.A., Wrenger, C., Groves, M.R.
登録日2016-03-04
公開日2016-06-08
最終更新日2016-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 72, 2016
5MC7
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CRYSTAL STRUCTURE OF TRUNCATED HUMAN COATOMER PROTEIN COMPLEX, SUBUNIT Z1 (COPZ1)
分子名称:Coatomer subunit zeta-1
著者Lunev, S., Groves, M.R.
登録日2016-11-09
公開日2016-12-28
最終更新日2017-01-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of truncated human coatomer protein complex subunit zeta 1 (Cop zeta 1).
Acta Crystallogr F Struct Biol Commun, 73, 2017
6FBA
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CRYSTAL STRUCTURE OF TRUNCATED ASPARTATE TRANSCARBAMOYLASE FROM PLASMODIUM FALCIPARUM WITH BOUND INHIBITOR 2,3-NAPHTHALENEDIOL
分子名称:Aspartate transcarbamoylase, SULFATE ION, naphthalene-2,3-diol, ...
著者Lunev, S., Bosch, S.S., Batista, F.A., Wang, C., Wrenger, C., Groves, M.R.
登録日2017-12-18
公開日2018-02-21
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase.
Biochem. Biophys. Res. Commun., 497, 2018
5NL8
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PEX4 OF HANSENULA POLYMORPHA
分子名称:Ubiquitin-conjugating enzyme E2-21 kDa
著者Groves, M., Williams, C.
登録日2017-04-04
公開日2018-01-24
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex.
Biochem. Biophys. Res. Commun., 496, 2018
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