5NFR

Crystal structure of malate dehydrogenase from Plasmodium falciparum (PfMDH)

Summary for 5NFR

Entry DOI	10.2210/pdb5nfr/pdb
Descriptor	Malate dehydrogenase, CITRIC ACID (2 entities in total)
Functional Keywords	malate metabolism, dehydrogenase, plasmodium falciparum, oligomerisation, oxidoreductase
Biological source	Plasmodium falciparum (isolate 3D7)
Total number of polymer chains	16
Total formula weight	562313.36
Authors	Lunev, S.,Romero, A.R.,Batista, F.A.,Wrenger, C.,Groves, M.R. (deposition date: 2017-03-15, release date: 2018-01-31, Last modification date: 2024-01-17)
Primary citation	Lunev, S.,Butzloff, S.,Romero, A.R.,Linzke, M.,Batista, F.A.,Meissner, K.A.,Muller, I.B.,Adawy, A.,Wrenger, C.,Groves, M.R. Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro. PLoS ONE, 13:e0195011-e0195011, 2018 Cited by PubMed: 29694407 DOI: 10.1371/journal.pone.0195011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation