1BZH
Cyclic peptide inhibitor of human PTP1B
Summary for 1BZH
Entry DOI | 10.2210/pdb1bzh/pdb |
Descriptor | PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B), PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B INHIBITOR) (3 entities in total) |
Functional Keywords | phosphorylation-inhibitor complex, tyrosine phosphatase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 35725.51 |
Authors | Groves, M.R.,Yao, Z.J.,Burke Jr., T.R.,Barford, D. (deposition date: 1998-10-28, release date: 1999-02-16, Last modification date: 2023-11-15) |
Primary citation | Groves, M.R.,Yao, Z.J.,Roller, P.P.,Burke Jr., T.R.,Barford, D. Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics. Biochemistry, 37:17773-17783, 1998 Cited by PubMed: 9922143DOI: 10.1021/bi9816958 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report