1CZI
CHYMOSIN COMPLEX WITH THE INHIBITOR CP-113972
Summary for 1CZI
Entry DOI | 10.2210/pdb1czi/pdb |
Related PRD ID | PRD_000344 |
Descriptor | CHYMOSIN, CP-113972 (NORSTATINE-S-METHYL CYSTEINE-IODO-PHENYLALANINE-PROLINE) (3 entities in total) |
Functional Keywords | acid proteinase, aspartyl protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bos taurus (cattle) |
Total number of polymer chains | 2 |
Total formula weight | 36403.39 |
Authors | Groves, M.R.,Dhanaraj, V.,Pitts, J.E.,Badasso, M.,Hoover, D.,Nugent, P.,Blundell, T.L. (deposition date: 1997-01-15, release date: 1997-04-01, Last modification date: 2023-11-15) |
Primary citation | Groves, M.R.,Dhanaraj, V.,Badasso, M.,Nugent, P.,Pitts, J.E.,Hoover, D.J.,Blundell, T.L. A 2.3 A resolution structure of chymosin complexed with a reduced bond inhibitor shows that the active site beta-hairpin flap is rearranged when compared with the native crystal structure. Protein Eng., 11:833-840, 1998 Cited by PubMed: 9862200DOI: 10.1093/protein/11.10.833 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report