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5Z7L
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CRYSTAL STRUCTURE OF NDP52 SKICH REGION IN COMPLEX WITH NAP1
Descriptor:Calcium-binding and coiled-coil domain-containing protein 2, 5-azacytidine-induced protein 2, GLYCEROL
Authors:Fu, T., Pan, L.F.
Deposit date:2018-01-29
Release date:2019-01-02
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5Z7A
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CRYSTAL STRUCTURE OF NDP52 SKICH REGION
Descriptor:Calcium-binding and coiled-coil domain-containing protein 2, SULFATE ION, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ...
Authors:Pan, L.F., Fu, T., Liu, J.P., Xie, X.Q.
Deposit date:2018-01-27
Release date:2019-01-02
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5Z7G
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CRYSTAL STRUCTURE OF TAX1BP1 SKICH REGION IN COMPLEX WITH NAP1
Descriptor:Tax1-binding protein 1, 5-azacytidine-induced protein 2, GLYCEROL
Authors:Pan, L.F., Fu, T., Liu, J.P., Xie, X.Q., Wang, Y.L., Hu, S.C.
Deposit date:2018-01-28
Release date:2019-01-02
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5GP7
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STRUCTURAL BASIS FOR THE BINDING BETWEEN TANKYRASE-1 AND USP25
Descriptor:Tankyrase-1, Ubiquitin carboxyl-terminal hydrolase 25, GLYCEROL
Authors:Liu, J., Xu, D., Fu, T., Pan, L.
Deposit date:2016-08-01
Release date:2017-07-12
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:USP25 regulates Wnt signaling by controlling the stability of tankyrases
Genes Dev., 31, 2017
5JQE
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CRYSTAL STRUCTURE OF CASPASE8 TDED
Descriptor:Sugar ABC transporter substrate-binding protein,Caspase-8 chimera
Authors:Fu, T., Li, Y., Lu, A., Wu, H.
Deposit date:2016-05-04
Release date:2016-10-26
Last modified:2018-02-21
Method:X-RAY DIFFRACTION (3.157 Å)
Cite:Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.
Mol. Cell, 64, 2016
2NA6
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TRANSMEMBRANE DOMAIN OF MOUSE FAS/CD95 DEATH RECEPTOR
Descriptor:Tumor necrosis factor receptor superfamily member 6
Authors:Fu, Q., Chou, J.J., Wu, H., Fu, T., Membrane Protein Structures by Solution NMR (MPSbyNMR)
Deposit date:2015-12-21
Release date:2016-01-27
Last modified:2016-03-02
Method:SOLUTION NMR
Cite:Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor.
Mol.Cell, 61, 2016
6NHW
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STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE DEATH RECEPTOR 5 - DIMER OF TRIMER
Descriptor:Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J., Pan, L., Fu, Q., Zhao, L., Chen, W., Piai, A., Fu, T., Wu, H.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
6NHY
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STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE DEATH RECEPTOR 5 MUTANT (G217Y) - TRIMER ONLY
Descriptor:Tumor necrosis factor receptor superfamily member 10B
Authors:Chou, J.J., Pan, L., Zhao, L., Chen, W., Piai, A., Fu, T., Wu, H., Liu, Z.
Deposit date:2018-12-24
Release date:2019-02-27
Last modified:2019-03-20
Method:SOLUTION NMR
Cite:Higher-Order Clustering of the Transmembrane Anchor of DR5 Drives Signaling.
Cell, 176, 2019
6N1H
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CRYO-EM STRUCTURE OF ASC-CARD FILAMENT
Descriptor:Apoptosis-associated speck-like protein containing a CARD
Authors:Li, Y., Fu, T., Wu, H.
Deposit date:2018-11-08
Release date:2018-12-05
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6N1I
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CRYO-EM STRUCTURE OF NLRC4-CARD FILAMENT
Descriptor:NLR family CARD domain-containing protein 4
Authors:Li, Y., Fu, T., Wu, H.
Deposit date:2018-11-08
Release date:2018-12-05
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4O7Q
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CRYSTAL STRUCTURE OF THE F27G AIM2 PYRIN DOMAIN MUTANT AND SIMILARITIES OF ITS SELF-ASSOCIATION TO DED/DED INTERACTIONS
Descriptor:Interferon-inducible protein AIM2
Authors:Lu, A., Kabaleeswaran, V., Wu, H.
Deposit date:2013-12-26
Release date:2014-02-19
Last modified:2014-04-23
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal Structure of the F27G AIM2 PYD Mutant and Similarities of Its Self-Association to DED/DED Interactions.
J.Mol.Biol., 426, 2014
4ZJB
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CRYSTAL STRUCTURE OF (3R)-HYDROXYACYL-ACYL CARRIER PROTEIN DEHYDRATASE(FABZ) IN COMPLEX WITH HOLO-ACP FROM HELICOBACTER PYLORI
Descriptor:3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, Acyl carrier protein, CITRIC ACID, ...
Authors:Zhang, L., Zhang, L., Shen, X., Jiang, H.
Deposit date:2015-04-29
Release date:2016-11-02
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis.
Cell Res., 26, 2016
5X0W
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MOLECULAR MECHANISM FOR THE BINDING BETWEEN SHARPIN AND HOIP
Descriptor:E3 ubiquitin-protein ligase RNF31, Sharpin
Authors:Liu, J., Li, F., Cheng, X., Pan, L.
Deposit date:2017-01-23
Release date:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly
Cell Rep, 21, 2017