5JQE

Crystal structure of caspase8 tDED

Summary for 5JQE

• Entry DOI: 10.2210/pdb5jqe/pdb
• Descriptor: Sugar ABC transporter substrate-binding protein,Caspase-8 chimera (1 entity in total)
• Functional Keywords: apoptosis, hydrolase
• Biological source: Escherichia coli, Homo sapiens (Human)
• Cellular location: Cytoplasm: Q14790
• Total number of polymer chains: 1
• Total formula weight: 63706.39

Authors

Fu, T.,Li, Y.,Lu, A.,Wu, H. (deposition date: 2016-05-04, release date: 2016-10-26, Last modification date: 2024-04-03)

• Primary citation: Fu, T.M.,Li, Y.,Lu, A.,Li, Z.,Vajjhala, P.R.,Cruz, A.C.,Srivastava, D.B.,DiMaio, F.,Penczek, P.A.,Siegel, R.M.,Stacey, K.J.,Egelman, E.H.,Wu, H.; Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex.; Mol. Cell, 64:236-250, 2016; PubMed: 27746017; DOI: 10.1016/j.molcel.2016.09.009

Experimental method

X-RAY DIFFRACTION (3.157 Å)