5JQE

Crystal structure of caspase8 tDED

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Sugar ABC transporter substrate-binding protein,Caspase-8 chimera	polymer	565	63706.4	1	UniProt (A0A0L7A8Z3) UniProt (Q14790) Pfam (PF01547) Pfam (PF01335) UniProt (by SIFTS) (P0AEX9) In PDB	Escherichia coli Homo sapiens (Human)	CASP-8,Apoptotic cysteine protease,Apoptotic protease Mch-5,CAP4,FADD-homologous ICE/ced-3-like protease,FADD-like ICE,FLICE,ICE-like apoptotic protease 5,MORT1-associated ced-3 homolog,MACH

Sequence modifications

A: 13 - 379 (UniProt: A0A0L7A8Z3)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Gly 11	-	expression tag
Thr 12	-	expression tag
Thr 14	Ile 28	linker
Ala 374	Lys 388	linker
Ala 375	Asp 389	linker
His 379	Arg 393	linker

A: 1001 - 1186 (UniProt: Q14790)

PDB	External Database	Details
Gly 1122	Phe 122	conflict
Gly 1123	Leu 123	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63706.4
All*	Total formula weight	63706.4

*Water molecules are not included.