Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1PJN
DownloadVisualize
BU of 1pjn by Molmil
Mouse Importin alpha-bipartite NLS N1N2 from Xenopus laevis phosphoprotein Complex
Descriptor: Histone-binding protein N1/N2, Importin alpha-2 subunit
Authors:Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B.
Deposit date:2003-06-03
Release date:2003-08-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha
J.Biol.Chem., 278, 2003
1PJM
DownloadVisualize
BU of 1pjm by Molmil
Mouse Importin alpha-bipartite NLS from human retinoblastoma protein Complex
Descriptor: Importin alpha-2 subunit, Retinoblastoma-associated protein
Authors:Fontes, M.R.M, Teh, T, Jans, D, Brinkworth, R.I, Kobe, B.
Deposit date:2003-06-03
Release date:2003-08-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha
J.Biol.Chem., 278, 2003
1Q1S
DownloadVisualize
BU of 1q1s by Molmil
Mouse Importin alpha- phosphorylated SV40 CN peptide complex
Descriptor: Importin alpha-2 subunit, Large T antigen
Authors:Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
1Q1T
DownloadVisualize
BU of 1q1t by Molmil
Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex
Descriptor: Importin alpha-2 subunit, Large T antigen
Authors:Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
Deposit date:2003-07-22
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
8DND
DownloadVisualize
BU of 8dnd by Molmil
Crystal structure of Bothrops pirajai Piratoxin-I (PrTX-I) and synthetic inhibitor Varespladib (LY315920)
Descriptor: ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, Basic phospholipase A2 homolog piratoxin-1, SULFATE ION
Authors:Salvador, G.H.M, Fontes, M.R.M.
Deposit date:2022-07-11
Release date:2023-08-02
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.018 Å)
Cite:Structural basis of the myotoxic inhibition of the Bothrops pirajai PrTX-I by the synthetic varespladib.
Biochimie, 207, 2023
3L3Q
DownloadVisualize
BU of 3l3q by Molmil
Mouse importin alpha-pepTM NLS peptide complex
Descriptor: CITRATE ANION, Importin subunit alpha-2, pepTM
Authors:Takeda, A.A.S, Kobe, B, Fontes, M.R.M.
Deposit date:2009-12-17
Release date:2010-04-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Probing the specificity of binding to the major nuclear localization sequence-binding site of importin-alpha using oriented peptide library screening.
J.Biol.Chem., 285, 2010
7TMY
DownloadVisualize
BU of 7tmy by Molmil
Structure of Mouse Importin alpha NEIL3 NLS Peptide Complex
Descriptor: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 3
Authors:Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M.
Deposit date:2022-01-20
Release date:2023-08-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
7TMX
DownloadVisualize
BU of 7tmx by Molmil
Structure of Mouse Importin alpha NEIL1 NLS Peptide Complex
Descriptor: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 1
Authors:Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M.
Deposit date:2022-01-20
Release date:2023-08-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
6MQF
DownloadVisualize
BU of 6mqf by Molmil
Myotoxin II from Bothrops moojeni complexed with Acetylsalicylic acid
Descriptor: 2-(ACETYLOXY)BENZOIC ACID, Basic phospholipase A2 homolog 2, DIMETHYL SULFOXIDE
Authors:Salvador, G.H.M, Fontes, M.R.M.
Deposit date:2018-10-09
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.693 Å)
Cite:Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A2-like proteins using functional, structural and bioinformatics approaches.
Sci Rep, 9, 2019
6P6E
DownloadVisualize
BU of 6p6e by Molmil
Structure of Mouse Importin alpha - PAC3 NLS peptide complex
Descriptor: Importin subunit alpha-1, PAC3 NLS
Authors:Bernardes, N.E, Silva, T.D, Fukuda, C.A, Oliveira, H.C, Fontes, M.R.M.
Deposit date:2019-06-03
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Comparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha.
Sci Rep, 10, 2020
6MQD
DownloadVisualize
BU of 6mqd by Molmil
Myotoxin II from Bothrops moojeni complexed with Rosmarinic Acid
Descriptor: (2R)-3-(3,4-dihydroxyphenyl)-2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propanoic acid, Basic phospholipase A2 homolog 2
Authors:Salvador, G.H.M, Fontes, M.R.M.
Deposit date:2018-10-09
Release date:2019-03-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A2-like proteins using functional, structural and bioinformatics approaches.
Sci Rep, 9, 2019
6P6A
DownloadVisualize
BU of 6p6a by Molmil
Structure of Mouse Importin alpha - NIT2 NLS peptide complex
Descriptor: Importin subunit alpha-1, Nitrogen catabolic enzyme regulatory protein
Authors:Bernardes, N.E, Fukuda, C.A, Silva, T.D, Oliveira, H.C, Fontes, M.R.M.
Deposit date:2019-06-03
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.151 Å)
Cite:Comparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha.
Sci Rep, 10, 2020
6PWH
DownloadVisualize
BU of 6pwh by Molmil
Cystal structure of Myotoxin II from Bothrops moojeni co-crystallized with Varespladib (LY315920)
Descriptor: ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, Basic phospholipase A2 homolog 2, DIMETHYL SULFOXIDE
Authors:Salvador, G.H.M, Fontes, M.R.M.
Deposit date:2019-07-23
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920).
Sci Rep, 9, 2019
6CE2
DownloadVisualize
BU of 6ce2 by Molmil
Crystal structure of Myotoxin I (MjTX-I) from Bothrops moojeni complexed to inhibitor suramin
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Basic phospholipase A2 homolog 1
Authors:Salvador, G.H.M, Fontes, M.R.M.
Deposit date:2018-02-10
Release date:2018-07-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism.
Sci Rep, 8, 2018
1PC9
DownloadVisualize
BU of 1pc9 by Molmil
Crystal Structure of BnSP-6, a Lys49-Phospholipase A2
Descriptor: BnSP-6
Authors:Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R.M.
Deposit date:2003-05-16
Release date:2004-06-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights.
Biochem.Biophys.Res.Commun., 311, 2003
7M60
DownloadVisualize
BU of 7m60 by Molmil
Structure of Mouse Importin alpha MLH1-S467A NLS Peptide Complex
Descriptor: DNA mismatch repair protein Mlh1 NLS peptide, Importin subunit alpha-1
Authors:De Oliveira, H.C, Da Silva, T.D, Fukuda, C.A, Fontes, M.R.M.
Deposit date:2021-03-25
Release date:2021-07-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
7LYE
DownloadVisualize
BU of 7lye by Molmil
Myotoxin I from Bothrops moojeni co-crystallized with synthetic inhibitor Varespladib (LY315920)
Descriptor: ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Basic phospholipase A2 homolog BomoTx
Authors:Salvador, G.H.M, Borges, R.J, Fontes, M.R.M.
Deposit date:2021-03-06
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.758 Å)
Cite:The synthetic varespladib molecule is a multi-functional inhibitor for PLA 2 and PLA 2 -like ophidic toxins.
Biochim Biophys Acta Gen Subj, 1865, 2021
3T0R
DownloadVisualize
BU of 3t0r by Molmil
Crystal Structure of MjTX-I, a myotoxic Lys49-phospholipase A2 from Bothrops moojeni
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Phospholipase A2 homolog 1
Authors:Salvador, G.H.M, Marchi-Salvador, D.P, Fontes, M.R.M.
Deposit date:2011-07-20
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Crystal Structure of MjTX-I, a myotoxic Lys49-phospholipase A2 from Bothrops moojeni
To be Published
4K09
DownloadVisualize
BU of 4k09 by Molmil
Crystal structure of BbTX-II from Bothrops brazili venom
Descriptor: BbTX-II
Authors:Fernandes, C.A.H, Comparetti, E.J, Borges, R.J, Fontes, M.R.M.
Deposit date:2013-04-03
Release date:2013-11-20
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.107 Å)
Cite:Structural bases for a complete myotoxic mechanism: Crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom.
Biochim.Biophys.Acta, 1834, 2013
4K06
DownloadVisualize
BU of 4k06 by Molmil
Crystal structure of MTX-II from Bothrops brazili venom complexed with polyethylene glycol
Descriptor: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MTX-II, ...
Authors:Fernandes, C.A.H, Comparetti, E.J, Borges, R.J, Fontes, M.R.M.
Deposit date:2013-04-03
Release date:2013-11-13
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural bases for a complete myotoxic mechanism: Crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom.
Biochim.Biophys.Acta, 1834, 2013
7RJI
DownloadVisualize
BU of 7rji by Molmil
BthTX-II variant b, from Bothrops jararacussu venom, complexed with stearic acid
Descriptor: BthTX-IIb, SODIUM ION, STEARIC ACID, ...
Authors:Borges, R.J, Fontes, M.R.M.
Deposit date:2021-07-21
Release date:2022-01-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:BthTX-II from Bothrops jararacussu venom has variants with different oligomeric assemblies: An example of snake venom phospholipases A 2 versatility.
Int.J.Biol.Macromol., 191, 2021
7RJZ
DownloadVisualize
BU of 7rjz by Molmil
BthTX-II variant a, from Bothrops jararacussu venom, complexed with benzoic acid
Descriptor: BENZOIC ACID, BthTX-IIa
Authors:Borges, R.J, Fontes, M.R.M.
Deposit date:2021-07-21
Release date:2022-01-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:BthTX-II from Bothrops jararacussu venom has variants with different oligomeric assemblies: An example of snake venom phospholipases A 2 versatility.
Int.J.Biol.Macromol., 191, 2021
7ROX
DownloadVisualize
BU of 7rox by Molmil
BthTX-I complexed with inhibitor MMV
Descriptor: 12-methoxy-Nb-methylvoachalotine, Basic phospholipase A2 homolog bothropstoxin-I
Authors:Borges, R.J, De Marino, I, Uson, I, Fontes, M.R.M.
Deposit date:2021-08-02
Release date:2022-11-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and functional studies of a snake venom phospholipase A 2 -like protein complexed to an inhibitor from Tabernaemontana catharinensis.
Biochimie, 206, 2023
6B84
DownloadVisualize
BU of 6b84 by Molmil
Crystal structure of Myotoxin II from Bothrops moojeni
Descriptor: Basic phospholipase A2 homolog 2, SULFATE ION
Authors:Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M.
Deposit date:2017-10-05
Release date:2018-10-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin.
Biochim Biophys Acta Proteins Proteom, 1866, 2018
6B83
DownloadVisualize
BU of 6b83 by Molmil
Crystal structure of Myotoxin II from Bothrops moojeni complexed to Caproic acid
Descriptor: Basic phospholipase A2 homolog 2, HEXANOIC ACID, SULFATE ION
Authors:Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M.
Deposit date:2017-10-05
Release date:2018-10-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin.
Biochim Biophys Acta Proteins Proteom, 1866, 2018

 

123>

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon