4K06

Crystal structure of MTX-II from Bothrops brazili venom complexed with polyethylene glycol

Summary for 4K06

• Entry DOI: 10.2210/pdb4k06/pdb
• Related: 2OK9 3CYL 3IQ3 4K09
• Descriptor: MTX-II, TRIETHYLENE GLYCOL, SULFATE ION, ... (6 entities in total)
• Functional Keywords: phospholipase a2, toxin
• Biological source: Bothrops brazili
• Cellular location: Secreted: 4K06
• Total number of polymer chains: 2
• Total formula weight: 28801.58

Authors

Fernandes, C.A.H.,Comparetti, E.J.,Borges, R.J.,Fontes, M.R.M. (deposition date: 2013-04-03, release date: 2013-11-13, Last modification date: 2013-11-27)

• Primary citation: Fernandes, C.A.H.,Comparetti, E.J.,Borges, R.J.,Huancahuire-Vega, S.,Ponce-Soto, L.A.,Marangoni, S.,Soares, A.M.,Fontes, M.R.M.; Structural bases for a complete myotoxic mechanism: Crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom.; Biochim.Biophys.Acta, 1834:2772-2781, 2013; PubMed: 24145104; DOI: 10.1016/j.bbapap.2013.10.009

Experimental method

X-RAY DIFFRACTION (2.08 Å)