1Q1T

Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex

Summary for 1Q1T

Related1IAL 1EJL 1PJM 1PJN 1EJY
DescriptorLarge T antigen, Importin alpha-2 subunit (3 entities in total)
Functional Keywordsimportin alpha/karyopherin alpha, nuclear localisation sequence (nls) recognition, phosphorylation, simian virus (sv40) large tumor-antigen (t-antigen) nls, x-ray crystal structure, protein transport
Biological sourceMus musculus (house mouse)
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Cellular locationHost nucleus P03070 P03070
Total number of polymer chains3
Total molecular weight55833.17
Authors
Fontes, M.R.M.,Teh, T.,Toth, G.,John, A.,Pavo, I.,Jans, D.A.,Kobe, B. (deposition date: 2003-07-22, release date: 2004-03-30, Last modification date: 2011-07-13)
Primary citation
Fontes, M.R.M.,Teh, T.,Toth, G.,John, A.,Pavo, I.,Jans, D.A.,Kobe, B.
Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375:339-349, 2003
PubMed: 12852786 (PDB entries with the same primary citation)
DOI: 10.1042/BJ20030510
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23414 0.7% 3.5% 4.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
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PDB entries from 2020-09-23