6CE2
Crystal structure of Myotoxin I (MjTX-I) from Bothrops moojeni complexed to inhibitor suramin
Summary for 6CE2
Entry DOI | 10.2210/pdb6ce2/pdb |
Related | 3T0R |
Descriptor | Basic phospholipase A2 homolog 1, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, ... (4 entities in total) |
Functional Keywords | myotoxin i, mjtx-i, pla2-like, suramin, toxin |
Biological source | Bothrops moojeni (Lance-headed viper) |
Total number of polymer chains | 2 |
Total formula weight | 29588.44 |
Authors | Salvador, G.H.M.,Fontes, M.R.M. (deposition date: 2018-02-10, release date: 2018-07-25, Last modification date: 2023-10-04) |
Primary citation | Salvador, G.H.M.,Dreyer, T.R.,Gomes, A.A.S.,Cavalcante, W.L.G.,Dos Santos, J.I.,Gandin, C.A.,de Oliveira Neto, M.,Gallacci, M.,Fontes, M.R.M. Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism. Sci Rep, 8:10317-10317, 2018 Cited by PubMed: 29985425DOI: 10.1038/s41598-018-28584-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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